Results 91 to 100 of about 4,341,821 (307)
Avian Influenza viruses (AIVs) present a public health risk, especially with seasonal vaccines offering limited protection. AIV H5N1 clade 2.3.4.4b has caused a multi-state outbreaks in the United States (US) poultry and cattle since March 2024, raising ...
Ahmed Mostafa +14 more
doaj +1 more source
The double-edged nature of trained immunity
Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.
Chrissy M Leopold Wager +1 more
doaj +1 more source
Lipidomics of host–pathogen interactions
The cell biology of intracellular pathogens (viruses, bacteria, eukaryotic parasites) has provided us with molecular information of host–pathogen interactions. As a result it is becoming increasingly evident that lipids play important roles at various stages of host–pathogen interactions.
openaire +2 more sources
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Immune correlates of protection against infection with Mycobacterium tuberculosis (Mtb) or against tuberculosis (TB) remain poorly defined. The ratio of colony-forming units (CFUs) to chromosomal equivalents (CEQs), [Formula: see text], recovered either ...
Allan D. Friesen, Vitaly V. Ganusov
doaj +1 more source
Hepatitis B virus (HBV) chronic infection is a critical risk factor for hepatocellular carcinoma. The innate immune response to HBV infection is a matter of debate. In particular, viral escape mechanisms are poorly understood.
Lise Lauterbach-Rivière +9 more
doaj +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Fluorescent protein-expressing Modified Vaccinia Ankara encoding T7 RNA polymerase
Efficient recovery of negative-stranded RNA viruses from plasmid cDNA requires robust bacteriophage T7 RNA polymerase expression, commonly supplied by Modified Vaccinia Ankara expressing T7 polymerase (MVA T7).
Nathaniel Jackson +3 more
doaj +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Susceptibility to Phytophthora ramorum in a key infectious host: Landscape variation in host genotype, host phenotype, and environmental factors [PDF]
• Sudden oak death is an emerging forest disease caused by the invasive pathogen Phytophthora ramorum. Genetic and environmental factors affecting susceptibility to P.
Hüberli, D. +7 more
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