Results 11 to 20 of about 713,544 (377)
RNA profiling in host–pathogen interactions [PDF]
Current Opinion in Microbiology, 2007 The development of novel anti-bacterial treatment strategies will be aided by an increased understanding of the interactions that take place between bacteria and host cells during infection. Global expression profiling using microarray technologies can help to describe and define the mechanisms required by bacterial pathogens to cause disease and the ...
Simon J. Waddell +2 more
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Mining Host-Pathogen Interactions [PDF]
, 2011 containing HPI information and another abstract that does not. Using a training set of pre-annotated abstracts, the system can then learn how to efficiently discriminate between these two abstract types. Moreover, the same characteristic features can be calculated for the individual sentences in the abstract.
Sneha Joshi +3 more
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Host–pathogen interactions and subversion of autophagy [PDF]
Essays in Biochemistry, 2017 Macroautophagy (‘autophagy’), is the process by which cells can form a double-membraned vesicle that encapsulates material to be degraded by the lysosome. This can include complex structures such as damaged mitochondria, peroxisomes, protein aggregates and large swathes of cytoplasm that can not be processed efficiently by other means of degradation ...
Alemu +104 more
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Membrane rafts in host–pathogen interactions
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2006 Central elements in the infection of mammalian cells with viral, bacterial and parasitic pathogens include the adhesion of the pathogen to surface receptors of the cell, recruitment of additional receptor proteins to the infection-site, a re-organization of the membrane and, in particular, the intracellular signalosome.
Erich Gulbins +3 more
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Serpin functions in host-pathogen interactions [PDF]
PeerJ, 2018 Serpins are a broadly distributed superfamily of protease inhibitors that are present in all kingdoms of life. The acronym, serpin, is derived from their function as potent ser ine p roteases in hibitors. Early studies of serpins focused on their functions in haemostasis since modulating serine proteases activities are essential for coagulation ...
Guoqing Pan +7 more
openaire +6 more sources
mBio, 2023 Sterile α motif and HD domain-containing protein 1 (SAMHD1) is a dNTP triphosphate triphosphohydrolase (dNTPase) and a potent restriction factor for immunodeficiency virus 1 (HIV-1), active in myeloid and resting CD4+ T cells.
Moritz Schüssler +7 more
doaj +1 more source
Revealing the molecular signatures of host-pathogen interactions. [PDF]
, 2011 Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co ...
C Herdtweck +53 more
core +22 more sources
mBio, 2022 Mycobacterium tuberculosis segregates within multiple subcellular niches with different biochemical and biophysical properties that, upon treatment, may impact antibiotic distribution, accumulation, and efficacy.
Pierre Santucci +7 more
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Scientific Reports, 2021 While considered an extracellular pathogen, Pseudomonas aeruginosa has been reported to be engulfed by macrophages in cellular and animal models. However, the role of macrophages in P. aeruginosa clearance in vivo remains poorly studied.
Malika Moussouni +4 more
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Animal Microbiome, 2022 Background Broilers are among the most common and dense poultry production systems, where antimicrobials have been used extensively to promote animal health and performance.
Ingrid Cárdenas-Rey +9 more
doaj +1 more source