Results 31 to 40 of about 803,197 (352)

Signatures of Pleiotropy, Economy and Convergent Evolution in a Domain-Resolved Map of Human–Virus Protein–Protein Interaction Networks [PDF]

, 2013
A central challenge in host-pathogen systems biology is the elucidation of general, systems-level principles that distinguish host-pathogen interactions from within-host interactions.
Franzosa, Eric A., Garamszegi, Sara, Xia, Yu   +2 more
core   +8 more sources

Refining Host-Pathogen Interactions: Organ-on-Chip Side of the Coin

Pathogens, 2021
Bioinspired organ-level in vitro platforms that recapitulate human organ physiology and organ-specific responses have emerged as effective technologies for infectious disease research, drug discovery, and personalized medicine.
Buket Baddal, P. Marrazzo
semanticscholar   +1 more source

Livestock abundance predicts vampire bat demography, immune profiles, and bacterial infection risk [PDF]

, 2018
Human activities create novel food resources that can alter wildlife–pathogen interactions. If resources amplify or dampen, pathogen transmission probably depends on both host ecology and pathogen biology, but studies that measure responses to ...
Altizer, Sonia, Becker, Daniel, Bentz, Alexandra B., Camus, Melinda S., Carrera, Jorge E., Chizhikov, Vladimir E., Czirjak, Gabor A., Fenton, M. Brock, Gilbert, Amy T., Navara, Kristen J., Recuenco, Sergio E., Simmons, Nancy B., Streicker, Daniel, Volokhov, Dmitriy V.   +13 more
core   +3 more sources

RNA profiling in host-pathogen interactions [PDF]

, 2007
The development of novel anti-bacterial treatment strategies will be aided by an increased understanding of the interactions that take place between bacteria and host cells during infection.
Belland, Boldrick, Brazma, Bryant, Chatterjee, Chaussabel, Dietrich, Eriksson, Faucher, Feezor, Granucci, Grifantini, Griffiths, Guillemin, Hinton, Huang, Huff, Jain, Jansen, Jenner, Joseph, Karakousis, Kato-Maeda, Kobayashi, Larocque, Lathem, Li, Li, Li, Liang, Liu, Lucchini, Mangan, McCaffrey, McMorran, Merrell, Motley, Mueller, Nau, Neil G Stoker, Orihuela, Pedron, Philip D Butcher, Rachman, Ramilo, Resnick, Revel, Sauvonnet, Schnappinger, Sebbane, Shi, Simon J Waddell, Smajs, Staudinger, Stintzi, Talaat, Virtaneva, Voyich, Xu, Yarwood   +59 more
core   +1 more source

Zebrafish Embryo Infection Model to Investigate Pseudomonas aeruginosa Interaction With Innate Immunity and Validate New Therapeutics

Frontiers in Cellular and Infection Microbiology, 2021
The opportunistic human pathogen Pseudomonas aeruginosa is responsible for a variety of acute infections and is a major cause of mortality in chronically infected patients with cystic fibrosis (CF). Considering the intrinsic and acquired resistance of P.
Stéphane Pont, Stéphane Pont, Anne-Béatrice Blanc-Potard, Anne-Béatrice Blanc-Potard   +3 more
doaj   +1 more source

Chlamydial infection from outside to inside [PDF]

, 2019
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic developmental cycle. Specific interactions with the host cell are crucial for the bacteria's survival and amplification because of the reduced chlamydial genome.
Gitsels, Arlieke, Sanders, Niek, Vanrompay, Daisy   +2 more
core   +2 more sources

Mycobacterium tuberculosis Modulates miR-106b-5p to Control Cathepsin S Expression Resulting in Higher Pathogen Survival and Poor T-Cell Activation

Frontiers in Immunology, 2017
The success of tuberculosis (TB) bacillus, Mycobacterium tuberculosis (Mtb), relies on the ability to survive in host cells and escape to immune surveillance and activation.
David Pires, Elliott M. Bernard, João Palma Pombo, Nuno Carmo, Catarina Fialho, Maximiliano Gabriel Gutierrez, Paulo Bettencourt, Elsa Anes   +7 more
doaj   +1 more source

Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]

, 2015
Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall, AK Neumann, B Amulic, B Enjalbert, B Hube, BN Gantner, C Jiménez-López, C Sasse, C Tokarski, CC Sheth, CF Urban, CGJ McKenzie, CJ Chrisman, D Armstrong-James, D Ermert, D Liebl, D Vijayan, DA Silva da, DC Savage, DJ Krysan, E Moreno-Ruiz, EK Szabo, FM Rudkin, G Chamilos, G Vande Velde, GD Brown, GD Brown, H Ma, H Ma, I Rubin-Bejerano, IE Frohner, J Behnsen, J Chandra, J Maertens, J Perlroth, J Voigt, JM Bain, JM Tam, Judith Bain, K Konig, K Schäfer, K Seider, KM Brothers, L Romani, L Romani, Lars-Peter Erwig, LE Lewis, LE Lewis, LG Tilney, LY Ngo, M Alvarez, MC Lorenz, MG Netea, MJ Patterson, MS Lionakis, MS Lionakis, N Papon, NAR Gow, Neil A. R. Gow, O Uzun, O Zaragoza, P Martino, P Miramón, Q Qian, R García-Rodas, RA Drummond, RD Diamond, RI Lehrer, S Bruns, S El-Kirat-Chatel, S Keppler-Ross, S Mitra, SA Johnston, SC Cheng, SE Heinsbroek, V Aimanianda, Wellington, Y Luo   +77 more
core   +1 more source

Nucleic acids enrichment of fungal pathogens to study host-pathogen interactions [PDF]

, 2019
Fungal infections, ranging from superficial to life-threatening infections, represent a major public health problem that affects 25% of the worldwide population.
Coucke, Paul, Guillemyn, Brecht, Rodriguez Sánchez, Antonio, Vaneechoutte, Mario   +3 more
core   +1 more source

First contact: the role of respiratory cilia in host-pathogen interactions in the airways

American Journal of Physiology - Lung cellular and Molecular Physiology, 2020
Respiratory cilia are the driving force of the mucociliary escalator, working in conjunction with secreted airway mucus to clear inhaled debris and pathogens from the conducting airways.
L. Kuek, R. Lee
semanticscholar   +1 more source