Results 71 to 80 of about 145,208 (274)

The Role of Cationic Polypeptides in Modulating HIV-1 Infection of the Cervicovaginal Mucosa

Antibiotics, 2014
The mucosa and overlying fluid of the female reproductive tract (FRT) are portals for the heterosexual transmission of HIV-1. Toward the ongoing development of topically applied microbicides and mucosal vaccines against HIV-1, it is evermore important to
Amy Liese Cole, Alexander M. Cole
doaj   +1 more source

Proteomic analysis of skin invasion by blood fluke larvae. [PDF]

, 2008
BackgroundDuring invasion of human skin by schistosome blood fluke larvae (cercariae), a multicellular organism breaches the epidermis, basement membrane, and dermal barriers of skin.
Braschi, Simon, Debnath, Moumita, Hansell, Elizabeth, Ingram, Jessica, Lim, KC, McKerrow, James H, Medzihradszky, Katalin F, Sajid, Mohammed   +7 more
core   +1 more source

LL‐37 Driven Phase Transition and Stacking in Oligolamellar Gram‐Negative Bacterial Membrane Models

Advanced Functional Materials, EarlyView.
This work establishes oligolamellar bacterial membrane models to investigate how LL‐37 disrupts the complex dual‐bilayer architecture of Gram‐negative bacteria. Combining SAXS, cryo‐TEM, electrophoretic mobility measurements, and coarse‐grained simulations, it reveals cardiolipin‐driven phase transitions leading to bicelle‐like structures and membrane ...
Bettina Tran, Diane C.A. Lima, Linda Sandblad, Madeleine Ramstedt, Thereza A. Soares, Stefan Salentinig   +5 more
wiley   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

A Review of Antimicrobial Activity of Dental Mesenchymal Stromal Cells: Is There Any Potential?

Frontiers in Oral Health, 2022
Antimicrobial defense is an essential component of host-microbial homeostasis and contributes substantially to oral health maintenance. Dental mesenchymal stromal cells (MSCs) possess multilineage differentiation potential, immunomodulatory properties ...
Oleh Andrukhov, Alice Blufstein, Alice Blufstein, Christian Behm   +3 more
doaj   +1 more source

Protective Microbiota: From Localized to Long-Reaching Co-Immunity [PDF]

, 2017
Resident microbiota do not just shape host immunity, they can also contribute to host protection against pathogens and infectious diseases. Previous reviews of the protective roles of the microbiota have focused exclusively on colonization resistance ...
Abt, Abt, Algburi, Altenhoefer, Altier, Anderson, Annuk, Asahara, Ashburner, Ayabe, Ayres, Barr, Barton, Bassis, Bassler, Becattini, Belkaid, Belkaid, Belkaid, Belkaid, Benson, Benveniste, Berg, Bevins, Birchenough, Birchenough, Blackburn, Bocci, Bohnhoff, Botes, Bouskra, Brandl, Braniste, Brenchley, Brestoff, Britton, Bron, Brugiroux, Budden, Buddington, Buffie, Buffie, Cani, Cani, Carey, Cash, Castagliuolo, Catford, Cebra, Cerf-Bensussan, Chatzidaki-Livanis, Chen, Chow, Chudnovskiy, Clarke, Clarke, Clarke, Cogen, Cogen, Cogen, Cotar, Cremer, Crost, Danielsson, Davidson, Davis, de Agüero, de Sablet, de Steenhuijsen Piters, Delhaes, Denny, Deriu, Dickson, Dickson, Dickson, Dickson, Donaldson, Donnet-Hughes, Eberl, El-Solh, Everett, Fagundes, Fardini, Fine, Fransen, Frantz, Franzenburg, Freter, Freter, Freter, Freter, Freter, Fubara, Fukuda, Gabryszewski, Gallichan, Gallo, Ganal, Gantois, Gauguet, Geva-Zatorsky, Gill, Gorjifard, Gutzeit, Henao-Mejia, Hersoug, Hibbing, Hooper, Hooper, Hooper, Hsiao, Ichinohe, Irie, Ivanov, Ivanov, Iwase, Kamada, Khosravi, Kinnunen, Knoop, Koch, Kolling, Kommineni, Laurent, Lawley, Levine, Little, Mack, Macpherson, Macpherson, Macpherson, Macpherson, Majlessi, Mallon, Maltby, Man, Mantis, Martins, Masson, Mazmanian, Mazmanian, McAleer, McKenney, Medzhitov, Melo, Mishra, Molloy, Murall, Mushin, Nagy, Nikkari, Oldroyd, Olier, Palm, Pamer, Pang, Perry, Pfeiffer, Pontier-Bres, Pradeu, Pradeu, Pradeu, Pérez-Santiago, Qin, Ramanan, Rasmussen, Rea, Rea, Ripert, Rizzetto, Robinson, Rolfe, Roossinck, Round, Ruhe, Råberg, Salzman, Sambanthamoorthy, Samuelson, Santagati, Santagati, Sassone-Corsi, Sassone-Corsi, Savage, Schamberger, Schieber, Schneider, Schuijt, Sharma, Shi, Shin, Shokouhfard, Shu, Siegrist, Soares, Sommer, Spees, Stapleton, Stappenbeck, Stecher, Stecher, Stinson, Strugnell, Sutyak Noll, Tanaka, Theriot, Tillmann, Tomkovich, Tomás, Tuomola, Ubeda, Underhill, Vaishnava, Valdés-Varela, Valdés-Varela, Valle, Van de Perre, van der Waaij, Vandecandelaere, Venkataraman, Villarino, Virgin, Virgin, Walker, Walsham, Weaver, Weingarden, Wexler, Whiteson, Wikoff, Willis, Wootton, Wright, Wu, Xiang, Yilmaz, Zagato, Zeng, Zipperer   +238 more
core   +4 more sources

Antimicrobial Peptides as Mediators of Epithelial Host Defense [PDF]

Pediatric Research, 1999
Mammalian epithelial surfaces are remarkable for their ability to provide critical physiologic functions in the face of frequent microbial challenges. The fact that these mucosal surfaces remain infection-free in the normal host suggests that highly effective mechanisms of host defense have evolved to protect these environmentally exposed tissues ...
K M, Huttner, C L, Bevins
openaire   +2 more sources

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Anti-antimicrobial Peptides FOLDING-MEDIATED HOST DEFENSE ANTAGONISTS:FOLDING-MEDIATED HOST DEFENSE ANTAGONISTS

The Journal of biological chemistry, 2013
Antimicrobial or host defense peptides are innate immune regulators found in all multicellular organisms. Many of them fold into membrane-bound α-helices and function by causing cell wall disruption in microorganisms. Herein we probe the possibility and functional implications of antimicrobial antagonism mediated by complementary coiled-coil ...
Ryan, Lloyd, Lamarre, Baptiste, Diu, Ting, Ravi, Jascindra, Judge, Peter J., Temple, Adam, Carr, Matthew, Cerasoli, Eleonora, Su, Bo, Jenkinson, Howard F., Martyna, Glenn, Crain, Jason, Watts, Anthony, Ryadnov, Maxim G.   +13 more
openaire   +4 more sources

Caenorhabditis elegans and probiotics interactions from a prolongevity perspective [PDF]

, 2019
Probiotics exert beneficial effects on host health through different mechanisms of action, such as production of antimicrobial substances, competition with pathogens, enhancement of host mucosal barrier integrity and immunomodulation.
Barbara Guantario, Chiara Devirgiliis, Daniela Uccelletti, Marianna Roselli, Paola Zinno, SCHIFANO, EMILY   +5 more
core   +1 more source