Results 21 to 30 of about 30,308 (277)

Microstructure and refinement mechanism of Al–5Ti–1B alloys

Fenmo yejin jishu, 2022
Two kinds of Al–5Ti–1B alloys were prepared by powder mixing + hot extrusion and powder mixing + gas atomization + hot extrusion, respectively. The microstructures of the Al–5Ti–1B alloys prepared by two kinds of processes were studied, and the grain ...
LI Yang, GUO Xu-qiang, XU Lei, LI Chang-yun, LIU Xiao-fei   +4 more
doaj   +1 more source

PLA/PA bio-blends: induced morphology by extrusion [PDF]

, 2019
The effect of processing conditions on the final morphology of Poly(Lactic Acid) (PLA) with bio-based Polyamide 10.10 (PA) 70/30 blends is analyzed in this paper. Two types of PLA were used: Commercial (neat PLA) and a rheologically modified PLA (PLAREx),
Abt, Tobias Martin, Cailloux, Jonathan, Carrasco Alonso, Félix Ángel, García Masabet, Violeta del Valle, Maspoch Rulduà, Mª Lluïsa, Santana Pérez, Orlando Onofre, Sánchez Soto, Miguel   +6 more
core   +2 more sources

Comparative study of the potential of poly(2-ethyl-2-oxazoline) as carrier in the formulation of amorphous solid dispersions of poorly soluble drugs [PDF]

, 2019
Despite the fact that solid dispersions are gaining momentum, the number of polymers that have been used as a carrier during the past 50 years is rather limited.
Boel, Eline, De la Rosa, Victor, Hoogenboom, Richard, Smeets, Annelies, Van den Mooter, Guy, Vergaelen, Maarten   +5 more
core   +1 more source

Pharmaceutical Hot Melt Extrusion [PDF]

Scientia Pharmaceutica, 2010
Hot Melt Extrusion, proven state-of-the-art technology in the field of plastics, is becoming increasingly important in the pharmaceutical industry. [...]
openaire   +1 more source

Novel Cleaning-in-Place Strategies for Pharmaceutical Hot Melt Extrusion

Pharmaceutics, 2020
To avoid any type of cross-contamination, residue-free production equipment is of utmost importance in the pharmaceutical industry. The equipment cleaning for continuous processes such as hot melt extrusion (HME), which has recently gained popularity in ...
Martin Spoerk, Ioannis Koutsamanis, Josip Matić, Simone Eder, Carolina Patricia Alva Zúñiga, Johannes Poms, Jesús Alberto Afonso Urich, Raymar Andreína Lara García, Klaus Nickisch, Karin Eggenreich, Andreas Berghaus, Kathrin Reusch, Yorick Relle, Johannes Khinast, Amrit Paudel   +14 more
doaj   +1 more source

Process induced degradation of carbamazepine during hot melt extrusion

British Journal of Pharmacy, 2023
The aim of this study was to evaluate hot melt extrudates of carbamazepine (CBZ) for presence of process induced degradation product iminostilbene (IMB) and quantifying using high performance liquid chromatography (HPLC). CBZ was used as model drug.
Sarbamangala Bose, Anant Paradkar, Adrian Kelly, Harika Magam   +3 more
doaj   +1 more source

Application of hot melt extrusion for improving bioavailability of artemisinin a thermolabile drug [PDF]

, 2017
Hot melt extrusion has been used to produce a solid dispersion of the thermolabile drug artemisinin. Formulation and process conditions were optimized prior to evaluation of dissolution and biopharmaceutical performance.
A. L. Kelly, A. Paradkar, C. Kulkarni, Ford JL., Jinadasa S., K. K. Singh, T. Gough, V. Jadhav, Wright CW.   +8 more
core   +2 more sources

Pharmaceutical Applications of Hot-Melt Extrusion: Continuous Manufacturing, Twin-Screw Granulations, and 3D Printing

Pharmaceutics, 2019
Recently, hot-melt extrusion (HME) techniques have been presented as innovative platforms to produce various pharmaceuticals [...]
Mohammed Maniruzzaman
doaj   +1 more source

The Development of Innovative Dosage Forms of the Fixed-Dose Combination of Active Pharmaceutical Ingredients

Pharmaceutics, 2022
The development of innovative forms of combination drugs is closely related to the invention of the multilayer tablet press, polymers for pharmaceutical applications, the hot-melt extrusion process, and 3D printing in the pharmaceutical industry. However,
Magdalena Janczura, Szymon Sip, Judyta Cielecka-Piontek   +2 more
doaj   +1 more source

Dissolution Enhancement of Raltegravir by Hot Melt Extrusion Technique

Iraqi Journal of Pharmaceutical Sciences, 2018
The objective of the study to develop an amorphous solid dispersion for poorly soluble raltegravir by hot melt extrusion (HME) technique. A novel solubility improving agent plasdone  s630 was utilized.
Ahmed S. Abdul Jabbar
doaj   +1 more source