Results 31 to 40 of about 917,915 (175)
Towards predicting the product quality in hot-melt extrusion: Pilot plant scale extrusion
International Journal of Pharmaceutics: X, 2021 Following our study on the impact of hot melt extrusion (HME) process conditions on the product quality, we expanded our investigation to assessing the effect of scale-up on the product quality.
Josip Matić +5 more
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MICROSTRUCTURE AND THERMAL STABILITY OF Al-Fe-X ALLOYS
Acta Metallurgica Slovaca, 2018 In this work, Al-11Fe, Al-7Fe-4Ni and Al-7Fe-4Cr (in wt. %) alloys were prepared by combination of casting and hot extrusion. Microstructures of as-cast alloys were composed of aluminium matrix with large and coarse intermetallics such as Al13Fe4 ...
Andrea Školáková +5 more
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PharmaceuticsBackground: Hot-melt extrusion (HME) is a promising technology for the manufacturing of drug products; however, its application is limited by elevated thermal and shear stresses that may induce degradation of thermolabile active pharmaceutical ...
Mark Mandrik +4 more
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Validation of Model-Based Melt Viscosity in Hot-Melt Extrusion Numerical Simulation
Pharmaceutics, 2018 A validation for the use of model-based melt viscosity in hot-melt extrusion numerical simulations was presented. Here, the melt viscosity of an amorphous solid dispersion (ASD) was calculated by using its glass transition temperature (Tg) and the ...
Esther S. Bochmann +2 more
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A Review on Hot Melt Extrusion Coupled Novel Drug Delivery Systems [PDF]
, 2022 The utilization of hot melt extrusion (HME) technology for new applications is increasing in recent years, as evidenced by the many published reports in the last five years.
Parvathaneni, Madhukiran +2 more
core +1 more source
Pharmaceutics, 2021 Additive manufacturing is widely used to produce highly complex structures. Moreover, this technology has proven its superiority in producing tools which can be used in different applications.
Bahaa Shaqour +13 more
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Novel Applications of Hot-Melt Extrusion Technology [PDF]
, 2018 Hot-melt extrusion, an adaptable technology, has established its position in a wide spectrum of manufacturing operations like amorphous solid dispersions, immediate and controlled oral formulations, implants, and taste masked products.
Bhagurkar, Ajinkya Moreshwar
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Hot Melt Extrusion Processing Parameters Optimization [PDF]
Processes, 2020 The aim of this study was to demonstrate the impact of processing parameters of the hot-melt extrusion (HME) on the pharmaceutical formulation properties. Carbamazepine (CBZ) was selected as a model water-insoluble drug. It was incorporated into Soluplus®, which was used as the polymeric carrier, to produce a solid dispersion model system.
Abdullah Alshetaili +3 more
openaire +1 more source
Modified release formulations manufactured by hot-melt extrusion [PDF]
, 2017 Hot-melt-extrusion has recently gained interest in pharmaceutical industrial manufacturing due to numerous advantages such as the possibility for continuous manufacturing, low cost of operation or the absence of organic solvents.
Maincent, Julien
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Recent advances in lubricants for hot metal forming: A review
Journal of Materials Research and TechnologyThe application of lubricants in hot metal forming processes is critical for reducing billet/die oxidation, lowering processing energy consumption, and improving die life, thereby enhancing the surface quality of the formed parts and the yield rate. This
Zhuang Sun +7 more
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