Results 21 to 30 of about 917,915 (175)
Journal of Materials Research and Technology, 2022 Grain refinement with a facile process without additional alloying is quite desired for strengthening the Al alloys. Using the melt spinning process, we obtained the ultra-fine grained foils of Al–Mg–Si–Cu alloy (AA6061), then the foils followed by hot ...
Shuoxun Jin +5 more
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Influence of degassing on hot-melt extrusion process [PDF]
European Journal of Pharmaceutical Sciences, 2015 The present study aimed to evaluate the effect of degassing on an extrusion process, with respect to extrudate quality and drug release properties. Processed formulations were extruded with and without a degassing vent port at various locations along the barrel. All the experiments were performed under constant processing temperature, feeding rate, and
Saad M, Alshahrani +5 more
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Разработка и регистрация лекарственных средств, 2023 Introduction. Ebastine is a second-generation antihistamine drug available in the form of orally disintegrating tablets and film-coated tablets. Ebastine substance exhibits high bioavailability, but low solubility in water and gastrointestinal tract ...
K. A. Gusev +7 more
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FROM CONCEPT TO DELIVERY: THE EVOLUTION AND APPLICATIONS OF HOT-MELT EXTRUSION IN PHARMACEUTICALS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut UniversityHot Melt Extrusion (HME) is an innovative approach that is currently receiving significant interest in the pharmaceutical sector for the manufacturing of various dosage forms.
Jigar Vyas, Nensi Raytthatha
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A Review of Dynamic Models of Hot-Melt Extrusion [PDF]
Processes, 2016 Hot-melt extrusion is commonly applied for forming products, ranging from metals to plastics, rubber and clay composites. It is also increasingly used for the production of pharmaceuticals, such as granules, pellets and tablets. In this context, mathematical modeling plays an important role to determine the best process operating conditions, but also ...
Grimard, Jonathan +2 more
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Application of Lipids in Hot Melt Extrusion Technology [PDF]
, 2023 Lipids are commonly used excipients in drug delivery for improving solubility of low soluble drugs, enhancing bioavailability through avoiding first pass metabolism through nanoparticulate approach, modifying the drug release, binders, permeation ...
Dindigala, Anil Kumar +3 more
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Novel Cleaning-in-Place Strategies for Pharmaceutical Hot Melt Extrusion
Pharmaceutics, 2020 To avoid any type of cross-contamination, residue-free production equipment is of utmost importance in the pharmaceutical industry. The equipment cleaning for continuous processes such as hot melt extrusion (HME), which has recently gained popularity in ...
Martin Spoerk +14 more
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Microstructure and refinement mechanism of Al–5Ti–1B alloys
Fenmo yejin jishu, 2022 Two kinds of Al–5Ti–1B alloys were prepared by powder mixing + hot extrusion and powder mixing + gas atomization + hot extrusion, respectively. The microstructures of the Al–5Ti–1B alloys prepared by two kinds of processes were studied, and the grain ...
LI Yang +4 more
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Process induced degradation of carbamazepine during hot melt extrusion
British Journal of Pharmacy, 2023 The aim of this study was to evaluate hot melt extrudates of carbamazepine (CBZ) for presence of process induced degradation product iminostilbene (IMB) and quantifying using high performance liquid chromatography (HPLC). CBZ was used as model drug.
Sarbamangala Bose +3 more
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Pharmaceutics, 2022 The development of innovative forms of combination drugs is closely related to the invention of the multilayer tablet press, polymers for pharmaceutical applications, the hot-melt extrusion process, and 3D printing in the pharmaceutical industry. However,
Magdalena Janczura +2 more
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