Results 151 to 160 of about 871,394 (166)

Development of a HPMC-based controlled release formulation with hot melt extrusion (HME)

Drug Development and Industrial Pharmacy, 2012
The objective of this study was to develop hydroxypropyl methylcellulose (HPMC) based controlled release (CR) formulations via hot melt extrusion (HME) with a highly soluble crystalline active pharmaceutical ingredient (API) embedded In the polymer phase.
Decheng, Ma, Abdenour, Djemai, Colleen M, Gendron, Hanmi, Xi, Michelle, Smith, Jessica, Kogan, Li, Li   +6 more
openaire   +2 more sources

The Hot Melt Extrusion (HME) in Pharmaceutical Technology: A Comprehensive Review

International Journal on Science and Technology
Hot Melt Extrusion (HME) is an innovative and versatile technology that has significantly impacted pharmaceutical formulation and drug delivery. Originally developed for the plastics industry, HME has been successfully adapted for pharmaceutical use due to its solvent-free and continuous processing capabilities.
Prashant Halagali -, Bhuvaneshwari R. Sharannavar -   +1 more
openaire   +1 more source

Taste masking of bitter APIs by using hot melt extrusion (HME) [PDF]

, 2011
PURPOSE\ud To investigate the potential of Hot-melt Extrusion (HME) for masking the taste of bitter cationic APIs when incorporated into different anionic polymer formulations through a possible taste masking mechanism attributed to intermolecular drug/polymer ionic interactions.\ud METHODS\ud The materials (Cetirizine HCl-CTZ, Propanolol HCl-PRP ...
Maniruzzaman, M., Boateng, J., Douroumis, D.   +2 more
openaire  

Continuous manufacturing of immediate release (IR) tablets by Hot-Melt Extrusion (HME) and injection molding (IM) techniques

2014
Purpose To evaluate hot melt extrusion (HME) and injection molding (IM) for the continuous manufacturing of IR tablets. Methods Polymeric fillers were mixed with plasticizers and functional adjuvants and/or a model drug were in some cases added to the formulation.
A. Melocchi, G. Loreti, F. Casati, M. Cerea, L. Zema, A. Gazzaniga   +5 more
openaire   +1 more source

Development of controlled release oral dosages by density gradient modification via three-dimensional (3D) printing and hot-melt extrusion (HME) technology

Journal of Drug Delivery Science and Technology, 2022
Zhiqing Hu, Pengchong Xu, Jiaxiang Zhang, Suresh Bandari, Michael A. Repka   +4 more
openaire   +1 more source

Coupling hot melt extrusion and fused deposition modeling: Critical properties for successful performance

Advanced Drug Delivery Reviews, 2021
Dinesh Nyavanandi, Michael Repka, Nagireddy Dumpa   +2 more
exaly  

Polymer Selection for Hot-Melt Extrusion Coupled to Fused Deposition Modelling in Pharmaceutics

Pharmaceutics, 2020
João F Pinto, Gabriela Garrastazu Pereira, Ana Isabel Fernandes   +2 more
exaly  

Development of a HPMC-based controlled release formulation with hot melt extrusion (HME)

Drug Development and Industrial Pharmacy, 2013
Hanmi Xi
exaly  

Design of the Amorphous Solid Dispersion (Asd) Drugs by Hot Melt Extrusion (Hme), for the Inhibition of Bone Graft Rejection

2024 IEEE 24th International Conference on Bioinformatics and Bioengineering (BIBE)
Djordje Milosevic, Marija Brankovic, Mihailo Jovanovic, Janko Djordjevic, Nenad Grujovic, Fatima Zivic   +5 more
openaire   +1 more source

Sustained release dosage form of noscapine HCl using hot melt extrusion (HME) technique: formulation and pharmacokinetics

Drug Delivery and Translational Research, 2020
Ketankumar Patel, Mandip Sachdeva, Arvind Bagde   +2 more
exaly