HOX Gene Expressions in Cultured Articular and Nasal Equine Chondrocytes [PDF]
Animals, 2021 Osteoarthritis the quality and span of life in horses. Previous studies focused on nasal cartilage as a possible source for autologous chondrocyte implantation (ACI) in cartilage defects in humans. “HOX gene-negative” nasal chondrocytes adapted articular
Christiane Storch +2 more
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Seeking Sense in the Hox Gene Cluster [PDF]
Journal of Developmental Biology, 2022 The Hox gene cluster, responsible for patterning of the head–tail axis, is an ancestral feature of all bilaterally symmetrical animals (the Bilateria) that remains intact in a wide range of species.
Stephen J. Gaunt
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Non-collinear Hox gene expression in bivalves and the evolution of morphological novelties in mollusks [PDF]
Scientific Reports, 2021 Hox genes are key developmental regulators that are involved in establishing morphological features during animal ontogeny. They are commonly expressed along the anterior–posterior axis in a staggered, or collinear, fashion.
David A. Salamanca-Díaz +3 more
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The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo. [PDF]
PLoS Genetics, 2022 Hox transcription factors play a conserved role in specifying positional identity during animal development, with posterior Hox genes typically repressing the expression of more anterior Hox genes.
John Isaac Murray +12 more
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Prolonging somatic cell proliferation through constitutive hox gene expression in C. elegans [PDF]
Nature Communications, 2023 hox genes encode a conserved family of homeodomain transcription factors that are essential to determine the identity of body segments during embryogenesis and maintain adult somatic stem cells competent to regenerate organs.
Svenia D. Heinze +4 more
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HOX gene expression in the developing human spine [PDF]
Nature CommunicationsPositional coding along the anterior-posterior axis is regulated by HOX genes, whose 3’ to 5’ expression correlates with location along this axis. The precise utilisation of HOX genes in different human cell types is not fully understood.
John E. G. Lawrence +19 more
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Evolutionary plasticity in nematode Hox gene complements and genomic loci arrangement [PDF]
Scientific ReportsHox genes are central to metazoan body plan formation, patterning and evolution, playing a critical role in cell fate decisions early in embryonic development in invertebrates and vertebrates.
Joseph Kirangwa +6 more
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Hox gene expression during development of the phoronid Phoronopsis harmeri [PDF]
EvoDevo, 2020 Background Phoronida is a small group of marine worm-like suspension feeders, which together with brachiopods and bryozoans form the clade Lophophorata. Although their development is well studied on the morphological level, data regarding gene expression
Ludwik Gąsiorowski, Andreas Hejnol
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Hox gene clusters in the mussel Mytilus coruscus: Implications for bivalves' evolution
Ecological Indicators, 2023 Hox genes encode transcription factors that are crucial regulators of various developmental processes, including patterning of the body axis and differentiation of cells, tissues and organs. They are organized in clusters in a wide range of Metazoans and
Chengrui Yan +8 more
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Molecular Oncology, 2021 In human, the 39 coding HOX genes and 18 referenced noncoding antisense transcripts are arranged in four genomic clusters named HOXA, B, C, and D. This highly conserved family belongs to the homeobox class of genes that encode transcription factors ...
Elisa Le Boiteux +10 more
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