Results 11 to 20 of about 2,727,731 (214)

Onychophoran Hox genes and the evolution of arthropod Hox gene expression [PDF]

open access: yesFrontiers in Zoology, 2014
Onychophora is a relatively small phylum within Ecdysozoa, and is considered to be the sister group to Arthropoda. Compared to the arthropods, that have radiated into countless divergent forms, the onychophoran body plan is overall comparably simple and does not display much in-phylum variation.
Janssen, Ralf   +3 more
openaire   +3 more sources

Hox genes and evolution [PDF]

open access: yesF1000Research, 2016
Hox proteins are a deeply conserved group of transcription factors originally defined for their critical roles in governing segmental identity along the antero-posterior (AP) axis in Drosophila .
Hrycaj, Steven M., Wellik, Deneen M.
openaire   +2 more sources

Genomic organization and expression demonstrate spatial and temporal Hox gene colinearity in the lophotrochozoan Capitella sp. I. [PDF]

open access: yesPLoS ONE, 2008
Hox genes define regional identities along the anterior-posterior axis in many animals. In a number of species, Hox genes are clustered in the genome, and the relative order of genes corresponds with position of expression in the body.
Andreas C Fröbius   +2 more
doaj   +1 more source

Reduction of Hox gene expression by histone H1 depletion. [PDF]

open access: yesPLoS ONE, 2012
The evolutionarily conserved homeotic (Hox) genes are organized in clusters and expressed collinearly to specify body patterning during embryonic development.
Yunzhe Zhang   +4 more
doaj   +1 more source

HOX genes in ovarian cancer [PDF]

open access: yesJournal of Ovarian Research, 2011
Abstract The HOX genes are a family of homeodomain-containing transcription factors that determine cellular identity during development. Here we review a number of recent studies showing that HOX genes are strongly expressed in ovarian cancer, and that in some cases the expression of specific HOX genes is sufficient to confer a particular ...
Kelly, ZL   +4 more
openaire   +5 more sources

Single nucleotide polymorphisms in microRNA binding sites on the HOX genes regulate carcinogenesis: An in-silico approach

open access: yesBiochemistry and Biophysics Reports, 2021
Homeobox proteins, encoded by HOX genes, are transcriptional factors playing a crucial role in the master regulatory pathway in the cells. Any mutations in HOX genes will affect the expression of its allied proteins. Such mutations were correlated to the
Waseem El-Huneidi   +2 more
doaj   +1 more source

Hox genes are not always Colinear [PDF]

open access: yesInternational Journal of Biological Sciences, 2006
The deuterostomes are the clade of animals for which we have the most detailed understanding of Hox cluster organisation. With the Hox cluster of amphioxus (Branchiostoma floridae) we have the best prototypical, least derived Hox cluster for the group ...
Ana Sara Monteiro, David E.K. Ferrier
doaj   +3 more sources

Evolution of Cyclostome Hox Clusters [PDF]

open access: yes, 2023
Hagfish and lampreys represent the only two lineages of agnathan (jawless) vertebrates that have survived to the present day, and both form the monophyletic group of cyclostomes, which is sister to the rest of the vertebrates, the gnathostomes (jawed ...
Christine Böhmer   +3 more
core   +1 more source

Hox gene cluster of the ascidian, Halocynthia roretzi, reveals multiple ancient steps of cluster disintegration during ascidian evolution

open access: yesZoological Letters, 2017
Background Hox gene clusters with at least 13 paralog group (PG) members are common in vertebrate genomes and in that of amphioxus. Ascidians, which belong to the subphylum Tunicata (Urochordata), are phylogenetically positioned between vertebrates and ...
Yuka Sekigami   +7 more
doaj   +1 more source

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice

open access: yesFrontiers in Cell and Developmental Biology, 2021
Body axial patterning develops via a rostral-to-caudal sequence and relies on the temporal colinear activation of Hox genes. However, the underlying mechanism of Hox gene temporal colinear activation remains largely elusive.
Feng Zhang   +12 more
doaj   +1 more source

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