Results 111 to 120 of about 80,068 (296)

The HPA axis and the genesis of chronic fatigue syndrome

, 2004
Many studies of patients with long-standing chronic fatigue syndrome (CFS) have found alterations to the hypothalamo-pituitary-adrenal (HPA) axis, including mild hypocortisolism, heightened negative feedback and blunted responses to challenge.
Cleare, A J; id_orcid
core   +1 more source

Mifepristone Accelerates HPA Axis Recovery in Secondary Adrenal Insufficiency [PDF]

, 2016
Context. Transient secondary adrenal insufficiency (SAI) is an expected complication following successful adenomectomy of ACTH-secreting pituitary adenomas or unilateral adrenalectomy for cortisol-secreting adrenal adenomas.
Pejman Cohan, Pejman Cohan
core   +1 more source

Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis

Acta Neuropathologica Communications, 2019
Inter-individual differences in cortisol production by the hypothalamus–pituitary–adrenal (HPA) axis are thought to contribute to clinical and pathological heterogeneity of multiple sclerosis (MS).
Jeroen Melief, Marie Orre, Koen Bossers, Corbert G. van Eden, Karianne G. Schuurman, Matthew R. J. Mason, Joost Verhaagen, Jörg Hamann, Inge Huitinga   +8 more
doaj   +1 more source

Multivariate Analysis of Hematological Stress Biomarkers and Welfare Domains in Organic and Intensive Pig Farming in Italy: A Pilot Study

Animal Research and One Health, EarlyView.
Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito, Talal Hassan, Antonio Marco Maisano, Stefania Bergagna, Cecilia Guasco, Barbara Miniscalco, Martina Tarantola, Elena Colombino, Claudio Caruso, Ahsan Muhammad, Silvia Mioletti, Laura Tomassone, Massimiliano Tursi, Cristina Vercelli, Giovanni Loris Alborali, Maria Teresa Capucchio   +15 more
wiley   +1 more source

Examining the Association Between Adverse Parenting Behaviour and Anterior Pituitary Gland Volume Development

BJPsych Open
Aims: Adverse parenting behaviours (APB) are considered to contribute to the risk of depression and other psychopathologies in young people via changes in the development of the neuroendocrine stress response, particularly of the hypothalamus-pituitary ...
Julia Kim, Elena Pozzi, Sarah Whittle
doaj   +1 more source

HPA axis function and diurnal cortisol in post-traumatic stress disorder: A systematic review

Neurobiology of Stress, 2019
Background: There is inconsistency in the literature regarding the nature of hypothalamic-pituitary-adrenal (HPA) axis functionality in post-traumatic stress disorder (PTSD). Purpose: The review aimed to investigate HPA axis functionality via the diurnal
Kathryn E. Speer, Stuart Semple, Nenad Naumovski, Nathan M. D'Cunha, Andrew J. McKune   +4 more
doaj   +1 more source

A Mouse Model of Depression‐Tumor Multimorbidity Reveals the Mechanism of Tumor Growth Accelerated by Depression

Animal Research and One Health, EarlyView.
Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren, Xinpei Wang, Wen Wang, Xingjiu Yang, Mengyuan Li, Jing Du, Ran Gao   +6 more
wiley   +1 more source

Hypothalamic‐pituitary‐adrenal axis recovery after intermediate‐acting glucocorticoid treatment in client‐owned dogs

Journal of Veterinary Internal Medicine
Background In dogs, duration of hypothalamic‐pituitary‐adrenal (HPA) axis suppression after systemic glucocorticoid treatment is reported to vary from a few days to up to 7 weeks after glucocorticoid discontinuation.
Francesca Del Baldo, Andrea Corsini, Antonio Maria Tardo, Alessandro Tirolo, Ada Sapignoli, Michele Tumbarello, Kateryna Vasylyeva, Federico Fracassi   +7 more
doaj   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin, Arthur N. Westover, Amy S. F. Lutz, Manish K. Jha   +3 more
wiley   +1 more source