Results 111 to 120 of about 802,913 (283)
Clinical Pharmacology &Therapeutics, EarlyView.Most clinical trial failures reflect unmeasured biological heterogeneity. Biography — chronic stress, adversity, trauma, and social isolation—is a neglected source of that heterogeneity, operating through the same molecular pathways drugs engage.
Ralph I. Horwitz
wiley +1 more source
Journal of Applied Sciences and Environmental ManagementThis review explores the intricate and bidirectional relationships between the hypothalamic-pituitary-adrenal (HPA) axis, sleep architecture and regulation, and the manifestation of various neuroendocrine disorders. The HPA axis, a critical component of
O. A. Udi
doaj +4 more sources
Validação do modelo de estresse por instabilidade social em camundongos suíços [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2013.O estresse é capaz de afetar vários processos fisiológicos e, portanto, é considerado como ...
Oliveira, Paula Macedo de
core
Deep Underground Science and Engineering, EarlyView.The fused data extracted from the distributed monitoring system as the data basis, combined with dynamic geological data, are imported into a deep learning model. As the geological conditions of mining and excavation change, the risk of water inrush at the working face is retrieved in real time.
Yongjie Li +4 more
wiley +1 more source
European Journal of Social Psychology, EarlyView.ABSTRACT The poor mental and physical health of trans‐ and gender‐diverse (TGD) young people is well established and commonly attributed to gender minority stress. Although recent research has shown that social support can mitigate these effects, less attention has been paid to the psychological processes through which this occurs.
Chase Staras +3 more
wiley +1 more source
Epileptic Disorders, EarlyView.Abstract Background Temporal lobe epilepsy (TLE) and functional dissociative seizures (FDS) are distinct conditions that share overlapping clinical, neuropsychiatric, and biological features, including depressive symptoms, obesity‐related metabolic dysregulation, and alterations in systemic inflammatory markers.
Betül Merd +4 more
wiley +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Epilepsia Open, EarlyView.Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
HPA-axis functioning in children: A psychobiological perspective [PDF]
, 2018 A major player of the human stress system is the hypothalamic-pituitary-adrenal (HPA) axis producing cortisol as primary hormonal end product. Alterations in cortisol production have been associated with health, making it important to understand HPA-axis
Simons, S.S.H.
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The HPA axis and the genesis of chronic fatigue syndrome
, 2004 Many studies of patients with long-standing chronic fatigue syndrome (CFS) have found alterations to the hypothalamo-pituitary-adrenal (HPA) axis, including mild hypocortisolism, heightened negative feedback and blunted responses to challenge.
Cleare, A J; id_orcid
core +1 more source
Epilepsia Open, EarlyView.Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira +5 more
wiley +1 more source