Results 131 to 140 of about 80,068 (296)

Sex differences in the murine HPA axis after acute and repeated restraint stress

open access: yesStress
Chronic stress and stress-related mental illnesses such as major depressive disorder (MDD) constitute some of the leading causes of disability worldwide with a higher prevalence in women compared to men.
Isabella Flor Nalepa   +6 more
doaj   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Hypothalamic-pituitary-adrenal (HPA) axis activity in patients with CFIDS and the effect of corticosteroid treatment on HPA axis activity

open access: yes, 2009
Objective: Chronic fatigue immune dysfunction syndrome (CFIDS) is a debilitating disease characterized by physical and mental fatigue for at least 6 months. The etiology of CFIDS is heterogeneous.
Izgi, Hasan Basri   +7 more
core  

Modeling the circadian regulation of HPA axis activity

open access: yes, 2018
The hypothalamic-pituitary-adrenal (HPA) axis constitutes the primary physiological stress response mechanism, with cortisol (corticosterone in rodents) being the major effector molecule of the HPA axis, mediating an array of metabolic and immune ...

core   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Spatio‐Temporal Dual‐Encoder Transformer for Short‐Term Regional Wind Power Forecasting

open access: yesEnergy Science &Engineering, EarlyView.
ST‐DualFormer separates temporal and spatial encoding to model complex dependencies in regional wind power forecasting. The fused dual‐stream representation enables accurate short‐term regional forecasts from multi‐farm meteorological and historical power data. The method achieved 5.25% nMAE and 7.53% nRMSE for three‐day‐ahead forecasting on real‐world
Jianfeng Che   +4 more
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska   +4 more
wiley   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

open access: yesFood Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

open access: yesFood Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

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