Results 131 to 140 of about 1,221,206 (330)

The HPA Axis During the Perinatal Period: Implications for Perinatal Depression.

Endocrinology, 2018
The transition to motherhood is characterized by some of the most pronounced endocrine changes a woman will experience in her lifetime. Unfortunately, matrescence is also a time in a woman's life when she is most susceptible to mental illness such as ...
M. Dickens, J. Pawluski
semanticscholar   +1 more source

Adverse Childhood Experiences in Autistic and Neurotypical Girls

Autism Research, EarlyView.
ABSTRACT Adverse childhood experiences (ACEs) are potentially traumatic, life‐altering events that occur in childhood with long‐term negative physical and/or mental health outcomes. Previous research, while limited and largely focused on males, suggests children with autism spectrum disorder (ASD) are at higher risk of experiencing ACEs than typically ...
Jon Ebert, Rachael A. Muscatello, Trey McGonigle, Simon Vandekar, Blythe A. Corbett   +4 more
wiley   +1 more source

Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis

Acta Neuropathologica Communications, 2019
Inter-individual differences in cortisol production by the hypothalamus–pituitary–adrenal (HPA) axis are thought to contribute to clinical and pathological heterogeneity of multiple sclerosis (MS).
Jeroen Melief, Marie Orre, Koen Bossers, Corbert G. van Eden, Karianne G. Schuurman, Matthew R. J. Mason, Joost Verhaagen, Jörg Hamann, Inge Huitinga   +8 more
doaj   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Hypothalamic‐pituitary‐adrenal axis recovery after intermediate‐acting glucocorticoid treatment in client‐owned dogs

Journal of Veterinary Internal Medicine
Background In dogs, duration of hypothalamic‐pituitary‐adrenal (HPA) axis suppression after systemic glucocorticoid treatment is reported to vary from a few days to up to 7 weeks after glucocorticoid discontinuation.
Francesca Del Baldo, Andrea Corsini, Antonio Maria Tardo, Alessandro Tirolo, Ada Sapignoli, Michele Tumbarello, Kateryna Vasylyeva, Federico Fracassi   +7 more
doaj   +1 more source

Examining the Association Between Adverse Parenting Behaviour and Anterior Pituitary Gland Volume Development

BJPsych Open
Aims: Adverse parenting behaviours (APB) are considered to contribute to the risk of depression and other psychopathologies in young people via changes in the development of the neuroendocrine stress response, particularly of the hypothalamus-pituitary ...
Julia Kim, Elena Pozzi, Sarah Whittle
doaj   +1 more source

The combined dexamethasone/CRH Test (DEX/CRH test) and prediction of acute treatment response in major depression.

PLoS ONE, 2009
BackgroundIn this study the predictive value of the combined dexamethasone/CRH test (DEX/CRH test) for acute antidepressant response was investigated.Methodology/principal findingsIn 114 depressed inpatients suffering from unipolar or bipolar depression (
Cornelius Schüle, Thomas C Baghai, Daniela Eser, Sibylle Häfner, Christoph Born, Sascha Herrmann, Rainer Rupprecht   +6 more
doaj   +1 more source

A Tilted Axis: Maladaptive Inflammation and HPA Axis Dysfunction Contribute to Consequences of TBI

Frontiers in Neurology, 2019
Each year approximately 1.7 million people sustain a traumatic brain injury (TBI) in the US alone. Associated with these head injuries is a high prevalence of neuropsychiatric symptoms including irritability, depression, and anxiety.
Z. Tapp, J. Godbout, O. Kokiko-Cochran
semanticscholar   +1 more source

Dynamic geo‐hydrogeological monitoring‐driven situational awareness for real‐time floor water inrush risk prediction in deep mining

Deep Underground Science and Engineering, EarlyView.
The fused data extracted from the distributed monitoring system as the data basis, combined with dynamic geological data, are imported into a deep learning model. As the geological conditions of mining and excavation change, the risk of water inrush at the working face is retrieved in real time.
Yongjie Li, Huiyong Yin, Fangying Dong, Tao Wu, Chao Zhang   +4 more
wiley   +1 more source

Is posttraumatic stress disorder specific to drug‐resistant epilepsy or a common feature of chronic disease? A comparative study with atrial fibrillation and type 1 diabetes

Epilepsia, EarlyView.
Abstract Objective Posttraumatic stress disorder (PTSD) is more prevalent in epilepsy than in the general population. However, it remains unclear whether this association is specific to epilepsy or a broader consequence of experiencing unpredictable acute episodes within chronic diseases.
Lisa‐Dounia Soncin, Capucine Rodet, Mina Aboulmakarim, Bernard Giusiano, Marie Arthuis, Jean‐Claude Deharo, Patrice Darmon, Olivia Ronsin, Sylvane Faure, Fabrice Bartolomei   +9 more
wiley   +1 more source