Results 11 to 20 of about 66,213 (258)

Ischemic Stroke, Glucocorticoids, and Remote Hippocampal Damage: A Translational Outlook and Implications for Modeling

Frontiers in Neuroscience, 2021
Progress in treating ischemic stroke (IS) and its delayed consequences has been frustratingly slow due to the insufficient knowledge on the mechanism. One important factor, the hypothalamic-pituitary-adrenocortical (HPA) axis is mostly neglected despite ...
Natalia V. Gulyaeva, Natalia V. Gulyaeva, Mikhail V. Onufriev, Mikhail V. Onufriev, Yulia V. Moiseeva   +4 more
doaj   +1 more source

Evaluation of the hypothalamo-pituitary-adrenal axis during the post-COVID-19 period in patients treated with steroids during the illness

Archives of Endocrinology and Metabolism, 2023
Objective: COVID-19 is a multisystem immunoinflammatory disorder, and the hypothalamo–pituitary-adrenal (HPA) axis may be affected by SARS-CoV-2 as well as by steroid treatment during the illness.
Shyam Sundar C M, Jayanthy Ramesh
doaj   +1 more source

Methamphetamine and the hypothalamic-pituitary-adrenal axis

Frontiers in Neuroscience, 2015
Psychostimulants such as methamphetamine (MA) induce significant alterations in the function of the hypothalamic-pituitary-adrenal (HPA) axis. These changes in HPA axis function are associated with altered stress-related behaviors and might contribute ...
Damian Gabriel Zuloaga, Jason eJacobskind, Jacob eRaber   +2 more
doaj   +1 more source

What’s new on the HPA axis? [PDF]

Intensive Care Medicine, 2015
The human body depends on an integrated neuro-endocrine response in order to adapt to external and internal stressors. In critical illness this stress response coordinates endocrine, neural, cardiovascular and immune systems with the aim to maximize survival chances.
Hofland, Hans, Bakker, Jan, Feelders, R.A.   +2 more
openaire   +3 more sources

A new model for the HPA axis explains dysregulation of stress hormones on the timescale of weeks

Molecular Systems Biology, 2020
Stress activates a complex network of hormones known as the hypothalamic–pituitary–adrenal (HPA) axis. The HPA axis is dysregulated in chronic stress and psychiatric disorders, but the origin of this dysregulation is unclear and cannot be explained by ...
Omer Karin, Moriya Raz, Avichai Tendler, Alon Bar, Yael Korem Kohanim, Tomer Milo, Uri Alon   +6 more
doaj   +1 more source

The role of the hypothalamic-pituitary-adrenal axis in depression across the female reproductive lifecycle: current knowledge and future directions

Frontiers in Endocrinology, 2023
The aim of this narrative review is to consolidate knowledge on the role of the hypothalamic-pituitary-adrenal (HPA) axis in depression pathophysiology at different reproductive stages across the female lifespan. Despite growing evidence about the impact
Liisa Hantsoo, Kathleen M. Jagodnik, Andrew M. Novick, Ritika Baweja, Ritika Baweja, Teresa Lanza di Scalea, Teresa Lanza di Scalea, Aysegul Ozerdem, Erin C. McGlade, Erin C. McGlade, Diana I. Simeonova, Diana I. Simeonova, Sharon Dekel, Sara L. Kornfield, Michelle Nazareth, Sandra J. Weiss   +15 more
doaj   +1 more source

Targeting the Arginine Vasopressin V1b Receptor System and Stress Response in Depression and Other Neuropsychiatric Disorders

Neuropsychiatric Disease and Treatment, 2023
Stephen J Kanes, Lara Dennie, Philip Perera EmbarkNeuro, Oakland, CA, USACorrespondence: Stephen J Kanes, EmbarkNeuro, Inc, 1111 Broadway, Suite 1300, Oakland, CA, 94607, USA, Tel +1 610 757 7821, Email steve.kanes@embarkneuro.comAbstract: A healthy ...
Kanes SJ, Dennie L, Perera P
doaj  

The Very Low-Dose Dexamethasone Suppression Test in the General Population: A Cross-Sectional Study. [PDF]

PLoS ONE, 2016
Determinants of the hypothalamic-pituitary-adrenal (HPA) axis functioning are increasingly explored in population-based studies. However, functional tests measuring the negative feedback of the HPA axis cannot easily be implemented into large ...
Nese Direk, Marieke J H J Dekker, Annemarie I Luik, Clemens Kirschbaum, Yolanda B de Rijke, Albert Hofman, Witte J G Hoogendijk, Henning Tiemeier   +7 more
doaj   +1 more source

HPA-axis and inflammatory reactivity to acute stress is related with basal HPA-axis activity [PDF]

Psychoneuroendocrinology, 2017
Inflammation is drawing attention as pathway between psychosocial stress and health, and basal HPA axis activity has been suggested to exert a consistent regulatory influence on peripheral inflammation. Here we studied the relationship between basal HPA axis activity and inflammatory and HPA axis acute stress reactivity.We recruited 48 healthy ...
Chen, Xuejie, Gianferante, Danielle, Hanlin, Luke, Fiksdal, Alexander, Breines, Juliana G, Thoma, Myriam V, Rohleder, Nicolas   +6 more
openaire   +2 more sources

Hypothalamus-Pituitary-Adrenal Dysfunction in Cholestatic Liver Disease

Frontiers in Endocrinology, 2018
The Hypothalamic-Pituitary-Adrenal (HPA) axis has an important role in maintaining the physiological homeostasis in relation to external and internal stimuli.
Anca D. Petrescu, Jessica Kain, Victoria Liere, Trace Heavener, Sharon DeMorrow, Sharon DeMorrow, Sharon DeMorrow   +6 more
doaj   +1 more source