Results 41 to 50 of about 1,221,206 (330)

Onset, timing, and exposure therapy of stress disorders: mechanistic insight from a mathematical model of oscillating neuroendocrine dynamics [PDF]

, 2016
The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the HPA axis are correlated with many stress-related diseases such as post-traumatic stress disorder (
Chou, Tom, D'Orsogna, Maria R., Kim, Lae Un   +2 more
core   +3 more sources

Hypothalamus-Pituitary-Adrenal Dysfunction in Cholestatic Liver Disease

Frontiers in Endocrinology, 2018
The Hypothalamic-Pituitary-Adrenal (HPA) axis has an important role in maintaining the physiological homeostasis in relation to external and internal stimuli.
Anca D. Petrescu, Jessica Kain, Victoria Liere, Trace Heavener, Sharon DeMorrow, Sharon DeMorrow, Sharon DeMorrow   +6 more
doaj   +1 more source

The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]

, 2020
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K, Saric-Bosanac, Suzana, Shi, Vivian Y, Sivamani, Raja K   +3 more
core  

Interaction of HPA axis genetics and early life stress shapes emotion recognition in healthy adults [PDF]

, 2018
Background: Early life stress (ELS) affects facial emotion recognition (FER), as well as the underlying brain network. However, there is considerable inter-individual variability in these ELS-caused alterations. As the hypothalamic-pituitary-adrenal (HPA)
Bajbouj, Malek, Dziobek, Isabel, Fan, Yan, Grimm, Simone, Gärtner, Matti, Hartling, Corinna, Trilla, Irene, Weigand, Anne   +7 more
core   +1 more source

The Influence of Hyperactivity of the Hypothalamic-pituitary-adrenal Axis and Hyperglycemia on the 5-HT2A Receptor-mediated Wet-dog Shake Responses in Rats [PDF]

, 2007
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis induces hyperglycemia and serotonin (5-HT)2A receptor supersensitivity. In the present study, to investigate the effect of hyperglycemia on the function of 5-HT2A receptors, we compared the 5-
Amano, Manabu, Araki, Hiroaki, Gomita, Yutaka, Kawasaki, Hiromu, Kitamura, Yoshihisa, Suemaru, Katsuya, Umeda, Yuichi, Yamaguchi, Takumi   +7 more
core   +1 more source

Brain mechanisms of HPA axis regulation: neurocircuitry and feedback in context Richard Kvetnansky lecture

Stress, 2020
Regulation of stress reactivity is a fundamental priority of all organisms. Stress responses are critical for survival, yet can also cause physical and psychological damage.
J. Herman, N. Nawreen, M. Smail, Evelin Cotella   +3 more
semanticscholar   +1 more source

Urbanicity, hypothalamic-pituitary-adrenal axis functioning, and behavioral and emotional problems in children: a path analysis

BMC Psychology, 2020
Background Urbanization is steadily increasing worldwide. Previous research indicated a higher incidence of mental health problems in more urban areas, however, very little is known regarding potential mechanisms underlying this association.
B. E. Evans, J. van der Ende, K. Greaves-Lord, A. C. Huizink, R. Beijers, C. de Weerth   +5 more
doaj   +1 more source

Nutraceutical Interventions for Post-Traumatic Stress Disorder in Animal Models: A Focus on the Hypothalamic–Pituitary–Adrenal Axis

Pharmaceuticals, 2022
Post-traumatic stress disorder (PTSD) occurs after exposure to traumatic events and is characterized by overwhelming fear and anxiety. Disturbances in the hypothalamic–pituitary–adrenal (HPA) axis are involved in the pathogenesis of mood disorders ...
Mudan Cai, Hee Ra Park, Eun Jin Yang
doaj   +1 more source

Cortisol patterns are associated with T cell activation in HIV. [PDF]

, 2012
ObjectiveThe level of T cell activation in untreated HIV disease is strongly and independently associated with risk of immunologic and clinical progression. The factors that influence the level of activation, however, are not fully defined.
Acree, Michael, Bacchetti, Peter, Deeks, Steven G, Epel, Elissa, Epling, Lorrie, Hecht, Frederick M, Kemeny, Margaret E, Kirschbaum, Clemens, Moran, Patricia, Patterson, Sarah, Sinclair, Elizabeth   +10 more
core   +3 more sources

Allostatic adaptation and personalized physiological trade-offs in the circadian regulation of the HPA axis: A mathematical modeling approach

Scientific Reports, 2019
The hypothalamic-pituitary-adrenal (HPA) axis orchestrates the physiological response to unpredictable acute stressors. Moreover, the HPA axis exhibits prominent circadian activity and synchronizes peripheral circadian clocks to daily environmental ...
Rohit Rao, Ioannis P. Androulakis
doaj   +1 more source