Results 51 to 60 of about 80,068 (296)

Early life stress, HPA axis, and depression. [PDF]

open access: yes, 2011
Considerable evidence from various studies suggests a preeminent role for early adverse experiences in the development of psychopathology, especially depression.
Tofoli,Sandra Marcia de Carvalho   +11 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity

open access: yesFrontiers in Neuroscience, 2021
The hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis caused by stress will inevitably disrupt the homeostasis of the neuroendocrine system and damage physiological functions.
Yu Wang   +6 more
doaj   +1 more source

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs   +15 more
wiley   +1 more source

Lower diurnal HPA-axis activity in male hypertensive and coronary heart disease patients predicts future CHD risk. [PDF]

open access: yes, 2023
BACKGROUND Coronary heart disease (CHD) and its major risk factor hypertension have both been associated with altered activity of the hypothalamus-pituitary-adrenal (HPA)-axis but the biological mechanisms underlying prospective associations with ...
Degroote, C.   +16 more
core   +1 more source

The HPA-axis and immune function in burnout [PDF]

open access: yes, 2007
Burnout results from chronic work stress. Its complaints may be related to HPA-axis disturbances or changes in immune function. In our studies the salivary cortisol awakening response, day-curve, and the suppressed level after dexamethasone intake were not different in a burned-out group compared to a control group.
Mommersteeg, P.M.C.   +3 more
openaire   +4 more sources

Investigation of Laser Ablation and Brush Pre‐Treatments for AlCu Cold Roll Bonding in Oxygen‐Free Conditions

open access: yesAdvanced Engineering Materials, EarlyView.
It is shown that laser ablation pretreatment under oxygen‐free conditions enables copper–aluminium bonding at significantly lower deformation degrees and improved properties compared to mechanical brushing. Laser ablation further increases interface contact area and induces favourable residual stress states and microstructural compatibility ...
Khemais Barienti   +11 more
wiley   +1 more source

Bouncing back: trauma and the HPA-axis in healthy adults

open access: yes, 2022
Background: Dysregulation of the hypothalamic–pituitary–adrenal (HPA)-axis is thought to underlie stress-related psychiatric disorders such as posttraumatic stress disorder (PTSD).
Ellen Renée Klaassens (14297782)
core   +1 more source

Maternal precarity and HPA axis functioning shape infant gut microbiota and HPA axis development in humans.

open access: yesPLoS ONE, 2021
BackgroundEarly life exposure to adverse environments, and maternal stress in particular, has been shown to increase risk for metabolic diseases and neurobehavioral disorders.
Johanna R Jahnke   +3 more
doaj   +1 more source

HPA axis function in alcohol use disorder: A systematic review and meta-analysis

open access: yesAddiction Neuroscience, 2023
Alcohol use disorder (AUD) is a culturally pervasive and often treatment resistant disorder. Stress is a major trigger for relapse in AUD. Allostasis in response to stress is governed by the hypothalamic-pituitary-adrenal axis (HPA axis).
Neil Dunne, Jo-Hanna Ivers
doaj   +1 more source

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