Early life adversity and serotonin transporter gene variation interact at the level of the adrenal gland to affect the adult hypothalamo-pituitary-adrenal axis [PDF]
, 2014 The short allelic variant of the serotonin transporter (5-HTT) promoter-linked polymorphic region (5-HTTLPR) has been associated with the etiology of major depression by interaction with early life stress (ELS). Furthermore, 5-HTTLPR has been associated
Deschamps, W. +7 more
core +2 more sources
Hypothalamic-Pituitary-Adrenal (HPA) axis [PDF]
, 2018 Increased adrenocortical secretion of hormones, primarily cortisol in depression, is one of the most consistent findings in neuropsychiatry. The maintenance of the internal homeostatic state of an individual is facilitated by the ability to circulate glucocorticoids to exert negative feedback on the secretion of hypothalamic-pituitary-adrenal (HPA ...
Young, Allan H., Juruena, Mario F.
openaire +3 more sources
Acta Psychologica, 2023 Psychopathic personality traits have been linked to low physiological arousal, particularly among high risk and forensic samples. A core indicator of physiological arousal is the activity of the hypothalamic-pituitary-adrenal (HPA) axis; however ...
Belma Isakovic +7 more
doaj +1 more source
Involvement of the hypothalamic-pituitary-thyroid axis and its interaction with the hypothalamic-pituitary-adrenal axis in the ontogeny of avian thermoregulation: a review [PDF]
, 2008 The emergence of thermoregulation in avian species is a complex matter in which neural as well as hormonal processes are involved. In a previous paper, the neural aspects of primary avian thermoregulation were discussed.
Baarendse, P.J.J. +5 more
core +2 more sources
Frontiers in Endocrinology, 2019 The study of the mechanisms underlying the increased vulnerability of the individual to stressful environmental factors in different age periods is of great relevance for prevention and effective treatment of stress-dependent diseases that are widespread
Nadezhda Goncharova +3 more
doaj +1 more source
Decreased Interleukin-4 Release from the Neurons of the Locus Coeruleus in Response to Immobilization Stress [PDF]
, 2016 It has been demonstrated that immobilization (IMO) stress affects neuroimmune systems followed by alterations of physiology and behavior. Interleukin-4 (IL-4), an anti-inflammatory cytokine, is known to regulate inflammation caused by immune challenge ...
An, Kyungeh +4 more
core +4 more sources
The attachment system and physiology in adulthood: normative processes, individual differences, and implications for health. [PDF]
, 2014 Attachment theory provides a conceptual framework for understanding intersections between personality and close relationships in adulthood. Moreover, attachment has implications for stress-related physiology and physical health.
Ainsworth +88 more
core +1 more source
European Journal of Developmental Psychology, 2020 This article reviews the evidence for theoretical models postulating that early adversity can set in motion a deleterious developmental cascade, involving changes in hypothalamic-pituitary-adrenal (HPA) axis activity that subsequently affect the ...
Christiane Wesarg +4 more
semanticscholar +1 more source
HPA axis participates in the osteoporosis symptoms of Parkinson's disease
生物医学转化, 2023 Parkinson's disease (PD) is considered as an independent risk factor of osteoporosis, which reveals a common pathology within the two disorders. The dysfunction of hypothalamic-pituitary-adrenal axis (HPA axis), which has been frequently reported in PD ...
Yang Chunying +5 more
doaj +1 more source
Inflammatory pain and corticosterone response in infant rats: effect of 5-HT1A agonist buspirone prior to gestational stress [PDF]
, 2013 Our researches have shown that gestational stress causes exacerbation of inflammatory pain in the offspring; the maternal 5-HT1A agonist buspirone before the stress prevents the adverse effect.
Aloisi, Anna Maria +5 more
core +2 more sources