Results 31 to 40 of about 844,564 (283)

A users guide to HPA axis research [PDF]

Physiology & Behavior, 2017
Glucocorticoid hormones (cortisol and corticosterone - CORT) are the effector hormones of the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic intercellular signal whose level predictably varies with time of day and dynamically increases with environmental and psychological stressors.
Robert L, Spencer, Terrence, Deak
openaire   +2 more sources

Nutraceutical Interventions for Post-Traumatic Stress Disorder in Animal Models: A Focus on the Hypothalamic–Pituitary–Adrenal Axis

Pharmaceuticals, 2022
Post-traumatic stress disorder (PTSD) occurs after exposure to traumatic events and is characterized by overwhelming fear and anxiety. Disturbances in the hypothalamic–pituitary–adrenal (HPA) axis are involved in the pathogenesis of mood disorders ...
Mudan Cai, Hee Ra Park, Eun Jin Yang
doaj   +1 more source

Urbanicity, hypothalamic-pituitary-adrenal axis functioning, and behavioral and emotional problems in children: a path analysis

BMC Psychology, 2020
Background Urbanization is steadily increasing worldwide. Previous research indicated a higher incidence of mental health problems in more urban areas, however, very little is known regarding potential mechanisms underlying this association.
B. E. Evans, J. van der Ende, K. Greaves-Lord, A. C. Huizink, R. Beijers, C. de Weerth   +5 more
doaj   +1 more source

Allostatic adaptation and personalized physiological trade-offs in the circadian regulation of the HPA axis: A mathematical modeling approach

Scientific Reports, 2019
The hypothalamic-pituitary-adrenal (HPA) axis orchestrates the physiological response to unpredictable acute stressors. Moreover, the HPA axis exhibits prominent circadian activity and synchronizes peripheral circadian clocks to daily environmental ...
Rohit Rao, Ioannis P. Androulakis
doaj   +1 more source

Hypothalamic-pituitary-adrenal axis responsivity during adolescence in relation to psychopathic personality traits later in life

Acta Psychologica, 2023
Psychopathic personality traits have been linked to low physiological arousal, particularly among high risk and forensic samples. A core indicator of physiological arousal is the activity of the hypothalamic-pituitary-adrenal (HPA) axis; however ...
Belma Isakovic, Bridget Bertoldi, Catherine Tuvblad, Sara Cucurachi, Adrian Raine, Laura Baker, Shichun Ling, Brittany E. Evans   +7 more
doaj   +1 more source

Glucocorticoid Negative Feedback in Regulation of the Hypothalamic-Pituitary-Adrenal Axis in Rhesus Monkeys With Various Types of Adaptive Behavior: Individual and Age-Related Differences

Frontiers in Endocrinology, 2019
The study of the mechanisms underlying the increased vulnerability of the individual to stressful environmental factors in different age periods is of great relevance for prevention and effective treatment of stress-dependent diseases that are widespread
Nadezhda Goncharova, Olga Chigarova, Natalia Rudenko, Tamara Oganyan   +3 more
doaj   +1 more source

HPA axis activity of Assamese macaques

, 2021
This database contains the data used to estimated HPA axis activity in wild Assamese macaques. The datasets support the research paper: "Early prenatal but not postnatal glucocorticoid exposure is associated with enhanced HPA axis activity into adulthood
Anza, Simone, Oliver Schülke, Michael Heistermann, Julia Ostner   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity

Frontiers in Neuroscience, 2021
The hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis caused by stress will inevitably disrupt the homeostasis of the neuroendocrine system and damage physiological functions.
Yu Wang, Jing Han, Jing Zhu, Mizhen Zhang, Minda Ju, Yueshan Du, Zhanzhuang Tian   +6 more
doaj   +1 more source

Stress, the hippocampus and the HPA axis: Implications for the development of psychotic disorders

, 2006
The experience of stress is commonly implicated in models of the onset of psychotic disorders. However, prospective studies investigating associations between biological markers of stress and the emergence of psychotic disorders are limited and ...
Katherine N. Thompson, Berger, Gregor, Gregor Berger, Wood, Stephen J., Pantelis, Christos, Phillips, Lisa J., Belinda Garner, Thompson, Kathrine N., Christos Pantelis, Garner, Belinda, Lisa J. Phillips, Stephen J. Wood, McGorry, Patrick D., Patrick D. Mcgorry   +13 more
core   +1 more source