Results 31 to 40 of about 802,913 (283)

Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and physical performance at older ages: an individual participant meta-analysis [PDF]

, 2012
The association between functioning of the hypothalamic pituitary adrenal (HPA) axis and physical performance at older ages remains poorly understood. We carried out meta-analyses to test the hypothesis that dysregulation of the HPA axis, as indexed by ...
Kumari, Meena, Cooper, R, Kumari, M., Gallacher, John, Gardner, Michael P., Halcyon Study Team, Peeters, Geeske, Ebrahim, S, Kuh, D., Ben-Shlomo, Y, Gardner, Mike P, Ebrahim, Shah, Kumari, M, Cooper, R., Martin, Richard M, Ebrahim, Shah B J, Sayer, A.A., Martin, RM, Gardner, M.P., Lightman, Stafford, Cooper, Rachel, Ben-Shlomo, Yoav, Ben-Shlomoa, Y., Gardner, Michael P, Gallacher, John Edward, Peeters, G, Sayer, AA, Martin, Richard M., Kivimaki, Mika, Kivimaki, M., Gallacher, J., Lightman, S., Deeg, D, Cooper, Cyrus, Gardner, MP, Ebrahim, S., Sayer, Avan Aihie, Kuh, Diana, Peeters, G., Deeg, D., Lightman, S, Gallacher, J, Cooper, C., Deeg, Dorly, Ben-Shlomo, Y., Kuh, D, Deeg, D.J.H., Kivimaki, M, Aihie Sayer, A, Cooper, C, Martin, R.M., Lightman, Stafford L   +51 more
core   +1 more source

Urbanicity, hypothalamic-pituitary-adrenal axis functioning, and behavioral and emotional problems in children: a path analysis

BMC Psychology, 2020
Background Urbanization is steadily increasing worldwide. Previous research indicated a higher incidence of mental health problems in more urban areas, however, very little is known regarding potential mechanisms underlying this association.
B. E. Evans, J. van der Ende, K. Greaves-Lord, A. C. Huizink, R. Beijers, C. de Weerth   +5 more
doaj   +1 more source

Sleep and the hypothalamic-pituitary-adrenocortical activity : biological processes associated with psychosocial adjustment during childhood and adolescence [PDF]

, 2015
: Sleep and the hypothalamic-pituitary-adrenocortical (HPA) activity are two biological processes that play a vital role for physical and mental health as well as general well-being.
Perkinson-Gloor, Nadine
core   +1 more source

Allostatic adaptation and personalized physiological trade-offs in the circadian regulation of the HPA axis: A mathematical modeling approach

Scientific Reports, 2019
The hypothalamic-pituitary-adrenal (HPA) axis orchestrates the physiological response to unpredictable acute stressors. Moreover, the HPA axis exhibits prominent circadian activity and synchronizes peripheral circadian clocks to daily environmental ...
Rohit Rao, Ioannis P. Androulakis
doaj   +1 more source

Hypothalamic-pituitary-adrenal axis responsivity during adolescence in relation to psychopathic personality traits later in life

Acta Psychologica, 2023
Psychopathic personality traits have been linked to low physiological arousal, particularly among high risk and forensic samples. A core indicator of physiological arousal is the activity of the hypothalamic-pituitary-adrenal (HPA) axis; however ...
Belma Isakovic, Bridget Bertoldi, Catherine Tuvblad, Sara Cucurachi, Adrian Raine, Laura Baker, Shichun Ling, Brittany E. Evans   +7 more
doaj   +1 more source

A users guide to HPA axis research [PDF]

Physiology & Behavior, 2017
Glucocorticoid hormones (cortisol and corticosterone - CORT) are the effector hormones of the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic intercellular signal whose level predictably varies with time of day and dynamically increases with environmental and psychological stressors.
Robert L, Spencer, Terrence, Deak
openaire   +2 more sources

Glucocorticoid Negative Feedback in Regulation of the Hypothalamic-Pituitary-Adrenal Axis in Rhesus Monkeys With Various Types of Adaptive Behavior: Individual and Age-Related Differences

Frontiers in Endocrinology, 2019
The study of the mechanisms underlying the increased vulnerability of the individual to stressful environmental factors in different age periods is of great relevance for prevention and effective treatment of stress-dependent diseases that are widespread
Nadezhda Goncharova, Olga Chigarova, Natalia Rudenko, Tamara Oganyan   +3 more
doaj   +1 more source

Chronic Stress-Associated Depressive Disorders: The Impact of HPA Axis Dysregulation and Neuroinflammation on the Hippocampus—A Mini Review [PDF]

International Journal of Molecular Sciences
Yu Lee, Chau Ling Tham, Ming Tatt Lee
exaly   +2 more sources

HPA axis participates in the osteoporosis symptoms of Parkinson's disease

生物医学转化, 2023
Parkinson's disease (PD) is considered as an independent risk factor of osteoporosis, which reveals a common pathology within the two disorders. The dysfunction of hypothalamic-pituitary-adrenal axis (HPA axis), which has been frequently reported in PD ...
Yang Chunying, Guo Lei, Yu Tieer, Xu Jinyan, Chen Li, Yao Lufeng   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source