HPA-axis and inflammatory reactivity to acute stress is related with basal HPA-axis activity [PDF]
Psychoneuroendocrinology, 2017 Inflammation is drawing attention as pathway between psychosocial stress and health, and basal HPA axis activity has been suggested to exert a consistent regulatory influence on peripheral inflammation. Here we studied the relationship between basal HPA axis activity and inflammatory and HPA axis acute stress reactivity.We recruited 48 healthy ...
Chen, Xuejie +6 more
openaire +4 more sources
Hypothalamic-Pituitary-Adrenal (HPA) axis [PDF]
, 2018 Increased adrenocortical secretion of hormones, primarily cortisol in depression, is one of the most consistent findings in neuropsychiatry. The maintenance of the internal homeostatic state of an individual is facilitated by the ability to circulate ...
Young, Allan H.; id_orcid +1 more
core +13 more sources
The combined dexamethasone/CRH Test (DEX/CRH test) and prediction of acute treatment response in major depression. [PDF]
PLoS ONE, 2009 BackgroundIn this study the predictive value of the combined dexamethasone/CRH test (DEX/CRH test) for acute antidepressant response was investigated.Methodology/principal findingsIn 114 depressed inpatients suffering from unipolar or bipolar depression (
Cornelius Schüle +6 more
doaj +2 more sources
Corticosterone oscillations during mania induction in the lateral hypothalamic kindled rat-Experimental observations and mathematical modeling. [PDF]
PLoS ONE, 2017 Changes in the hypothalamic-pituitary-adrenal (HPA) axis activity constitute a key component of bipolar mania, but the extent and nature of these alterations are not fully understood.
Osama A Abulseoud +6 more
doaj +1 more source
Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]
, 2014 Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Bloom, SR +5 more
core +1 more source
Impact of Gene-Gender Effects of Adrenergic Polymorphisms on Hypothalamic-Pituitary-Adrenal Axis Activity in Depressed Patients [PDF]
, 2008 Objective: There is overwhelming evidence that activation of the hypothalamic-pituitary-adrenal (HPA) system plays a major role in depression and cardiovascular disease in genetically susceptible individuals.
Bondy, Brigitta +7 more
core +1 more source
Frontiers in Neuroscience, 2021 Progress in treating ischemic stroke (IS) and its delayed consequences has been frustratingly slow due to the insufficient knowledge on the mechanism. One important factor, the hypothalamic-pituitary-adrenocortical (HPA) axis is mostly neglected despite ...
Natalia V. Gulyaeva +4 more
doaj +1 more source
Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans: a systematic review [PDF]
, 2009 BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
Pryce, C R +8 more
core +1 more source
Marijuana Use and Hypothalamic-Pituitary-Adrenal Axis Functioning in Humans
Frontiers in Psychiatry, 2018 Preclinical studies suggest cannabinoids affect functioning of the hypothalamic-pituitary-adrenal (HPA) axis, but little is known about the effects of marijuana (MJ) use on HPA axis functioning in humans. Since previous work indicates substances of abuse
Anita Cservenka +2 more
doaj +1 more source
Archives of Endocrinology and Metabolism, 2023 Objective: COVID-19 is a multisystem immunoinflammatory disorder, and the hypothalamo–pituitary-adrenal (HPA) axis may be affected by SARS-CoV-2 as well as by steroid treatment during the illness.
Shyam Sundar C M, Jayanthy Ramesh
doaj +1 more source