Results 21 to 30 of about 844,564 (283)

Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans: a systematic review [PDF]

, 2009
BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
Pryce, C R, Meinlschmidt, G., Meinlschmidt, M, Tegethoff, M., Pryce, C., Tegethoff, M, Christopher Pryce, Gunther Meinlschmidt, Marion Tegethoff, Tegethoff M, Meinlschmidt G, Pryce C   +11 more
core   +1 more source

Methamphetamine and the hypothalamic-pituitary-adrenal axis

Frontiers in Neuroscience, 2015
Psychostimulants such as methamphetamine (MA) induce significant alterations in the function of the hypothalamic-pituitary-adrenal (HPA) axis. These changes in HPA axis function are associated with altered stress-related behaviors and might contribute ...
Damian Gabriel Zuloaga, Jason eJacobskind, Jacob eRaber   +2 more
doaj   +1 more source

The role of the hypothalamic-pituitary-adrenal axis in depression across the female reproductive lifecycle: current knowledge and future directions

Frontiers in Endocrinology, 2023
The aim of this narrative review is to consolidate knowledge on the role of the hypothalamic-pituitary-adrenal (HPA) axis in depression pathophysiology at different reproductive stages across the female lifespan. Despite growing evidence about the impact
Liisa Hantsoo, Kathleen M. Jagodnik, Andrew M. Novick, Ritika Baweja, Ritika Baweja, Teresa Lanza di Scalea, Teresa Lanza di Scalea, Aysegul Ozerdem, Erin C. McGlade, Erin C. McGlade, Diana I. Simeonova, Diana I. Simeonova, Sharon Dekel, Sara L. Kornfield, Michelle Nazareth, Sandra J. Weiss   +15 more
doaj   +1 more source

The Very Low-Dose Dexamethasone Suppression Test in the General Population: A Cross-Sectional Study. [PDF]

PLoS ONE, 2016
Determinants of the hypothalamic-pituitary-adrenal (HPA) axis functioning are increasingly explored in population-based studies. However, functional tests measuring the negative feedback of the HPA axis cannot easily be implemented into large ...
Nese Direk, Marieke J H J Dekker, Annemarie I Luik, Clemens Kirschbaum, Yolanda B de Rijke, Albert Hofman, Witte J G Hoogendijk, Henning Tiemeier   +7 more
doaj   +1 more source

Targeting the Arginine Vasopressin V1b Receptor System and Stress Response in Depression and Other Neuropsychiatric Disorders

Neuropsychiatric Disease and Treatment, 2023
Stephen J Kanes, Lara Dennie, Philip Perera EmbarkNeuro, Oakland, CA, USACorrespondence: Stephen J Kanes, EmbarkNeuro, Inc, 1111 Broadway, Suite 1300, Oakland, CA, 94607, USA, Tel +1 610 757 7821, Email steve.kanes@embarkneuro.comAbstract: A healthy ...
Kanes SJ, Dennie L, Perera P
doaj  

A new model for the HPA axis explains dysregulation of stress hormones on the timescale of weeks

Molecular Systems Biology, 2020
Stress activates a complex network of hormones known as the hypothalamic–pituitary–adrenal (HPA) axis. The HPA axis is dysregulated in chronic stress and psychiatric disorders, but the origin of this dysregulation is unclear and cannot be explained by ...
Omer Karin, Moriya Raz, Avichai Tendler, Alon Bar, Yael Korem Kohanim, Tomer Milo, Uri Alon   +6 more
doaj   +1 more source

HPA-axis and inflammatory reactivity to acute stress is related with basal HPA-axis activity [PDF]

Psychoneuroendocrinology, 2017
Inflammation is drawing attention as pathway between psychosocial stress and health, and basal HPA axis activity has been suggested to exert a consistent regulatory influence on peripheral inflammation. Here we studied the relationship between basal HPA axis activity and inflammatory and HPA axis acute stress reactivity.We recruited 48 healthy ...
Chen, Xuejie, Gianferante, Danielle, Hanlin, Luke, Fiksdal, Alexander, Breines, Juliana G, Thoma, Myriam V, Rohleder, Nicolas   +6 more
openaire   +3 more sources

Familial longevity is marked by lower diurnal salivary cortisol levels: the leiden longevity study [PDF]

, 2012
Background Reported findings are inconsistent whether hypothalamic-pituitary-adrenal (HPA) signaling becomes hyperactive with increasing age, resulting in increasing levels of cortisol.
Westendorp, Rudi G J, Oei Nicole Y. L., Jansen, Steffy W M, Maier, A.B., de Craen, Anton J M, Akintola, Abimbola A., Pijl Hanno, Noordam, Raymond, Slagboom, P. Eline, Hanno Pijl, Diana van Heemst, Raymond Noordam, Jansen, SWM, Westendorp, RGJ, van der Grond Jeroen, Westendorp Rudi G. J., van Heemst, Diana, P Eline Slagboom, Noordam, R., Steffy W M Jansen, Heemst, D. van, Leiden Longevity Study group, Craen, A.J.M. de, van der Grond, J, Oei, Nicole YL, Jeroen van der Grond, van Heemst Diana, Anton J M de Craen, de Craen Anton J. M., Jansen, S.W.M., van Heemst, D, Noordam, R, de Craen, AJM, Akintola Abimbola A., Grond, J. van der, Pijl, Hanno, Oei, N.Y.L., Maier, Andrea B.; id_orcid, Rudi G J Westendorp, Maier, AB, Maier Andrea B., Pijl, H., Leiden Longevity Study Grp, Slagboom, PE, Noordam Raymond, Nicole Y L Oei, Jansen, Steffy, Slagboom, P.E., de Craen, Anton JM, Oei, Nicole Y L, Andrea B Maier, Jansen Steffy W. M., Oei, NYL, Westendorp, R.G.J., van der Grond, Jeroen, Akintola, Abimbola A, Abimbola A Akintola, Slagboom P. Eline, Akintola, A.A., Akintola, AA, Maier, Andrea B, Westerndorp, Rudi GJ, Pijl, H   +62 more
core   +1 more source

Cortisol awakening response in infants during the first six postnatal months and its relation to birth outcome [PDF]

, 2013
Context: The rise of cortisol concentrations after awakening is well documented in adults and children and commonly used as easily accessible marker of hypothalamic-pituitary-adrenal (HPA) reactivity.
Knierzinger, Nicole, Tegethoff, Marion, Meinlschmidt, Gunther, Meyer, Andrea H., Knierzinger N, Tegethoff M, Meyer AH, Meinlschmidt G   +7 more
core   +1 more source

Hypothalamus-Pituitary-Adrenal Dysfunction in Cholestatic Liver Disease

Frontiers in Endocrinology, 2018
The Hypothalamic-Pituitary-Adrenal (HPA) axis has an important role in maintaining the physiological homeostasis in relation to external and internal stimuli.
Anca D. Petrescu, Jessica Kain, Victoria Liere, Trace Heavener, Sharon DeMorrow, Sharon DeMorrow, Sharon DeMorrow   +6 more
doaj   +1 more source