The Involvement of Hypothalamus–Pituitary–Adrenal (HPA) Axis in Suicide Risk
Brain Sciences, 2020 Stress and Hypothalamic–Pituitary–Adrenal (HPA) axis dysregulation play a major role in various pathophysiological processes associated with both mood disorders and suicidal behavior.
Isabella Berardelli +5 more
doaj +1 more source
Dream Recall/Affect and the Hypothalamic–Pituitary–Adrenal Axis
Clocks & Sleep, 2021 In this concise review, we present an overview of research on dream recall/affect and of the hypothalamic–pituitary–adrenal (HPA) axis, discussing caveats regarding the action of hormones of the HPA axis (mainly cortisol and its free form, cortisol ...
Athanasios Tselebis +2 more
doaj +1 more source
Chronic stress suppresses the expression of cutaneous hypothalamic-pituitary-adrenocortical axis elements and melanogenesis. [PDF]
PLoS ONE, 2014 Chronic stress can affect skin function, and some skin diseases might be triggered or aggravated by stress. Stress can activate the central hypothalamic-pituitary-adrenocortical (HPA) axis, which causes glucocorticoid levels to increase. The skin has HPA
Silin Pang +5 more
doaj +1 more source
What’s new on the HPA axis? [PDF]
Intensive Care Medicine, 2015 The human body depends on an integrated neuro-endocrine response in order to adapt to external and internal stressors. In critical illness this stress response coordinates endocrine, neural, cardiovascular and immune systems with the aim to maximize survival chances.
Hofland, Hans +2 more
openaire +3 more sources
Corticosterone oscillations during mania induction in the lateral hypothalamic kindled rat-Experimental observations and mathematical modeling. [PDF]
PLoS ONE, 2017 Changes in the hypothalamic-pituitary-adrenal (HPA) axis activity constitute a key component of bipolar mania, but the extent and nature of these alterations are not fully understood.
Osama A Abulseoud +6 more
doaj +1 more source
Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]
, 2014 Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Bloom, SR +5 more
core +1 more source
Impact of Gene-Gender Effects of Adrenergic Polymorphisms on Hypothalamic-Pituitary-Adrenal Axis Activity in Depressed Patients [PDF]
, 2008 Objective: There is overwhelming evidence that activation of the hypothalamic-pituitary-adrenal (HPA) system plays a major role in depression and cardiovascular disease in genetically susceptible individuals.
Bondy, Brigitta +7 more
core +1 more source
Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans: a systematic review [PDF]
, 2009 BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
Pryce, C R +8 more
core +1 more source
Marijuana Use and Hypothalamic-Pituitary-Adrenal Axis Functioning in Humans
Frontiers in Psychiatry, 2018 Preclinical studies suggest cannabinoids affect functioning of the hypothalamic-pituitary-adrenal (HPA) axis, but little is known about the effects of marijuana (MJ) use on HPA axis functioning in humans. Since previous work indicates substances of abuse
Anita Cservenka +2 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Progress in treating ischemic stroke (IS) and its delayed consequences has been frustratingly slow due to the insufficient knowledge on the mechanism. One important factor, the hypothalamic-pituitary-adrenocortical (HPA) axis is mostly neglected despite ...
Natalia V. Gulyaeva +4 more
doaj +1 more source