Results 251 to 260 of about 802,913 (283)
Some of the next articles are maybe not open access.
Epigenetics/Programming in the
ABSTRACT The hypothalamic‐pituitary‐adrenal axis provides physiological adaptations to various environmental stimuli in mammals. These stimuli including maternal care, diet, immune challenge, stress, and others have the potential to stably modify or program the functioning of the HPA axis when experienced early in
Jan P, Buschdorf, Michael J, Meaney
openaire +2 more sources
An introduction to the HPA axis
2005Abstract ntegrity of the hypothalamo–pituitary–adrenal (HPA) axis is essential to survival of vertebrate species. This neuroendocrine axis functions to coordinate neural, endocrine and immune responses to diverse stressful stimuli that threaten homeostasis. The final products of activation of the HPA axis are the glucocorticoids that exert widespread
openaire +1 more source
2002
Glucocorticoids are essential for life. They influencing glucose metabolism, lipid metabolism, immune function, electrolyte and fluid homeostasis, development, the central nervous system, and the adrenal medulla. Glucocorticoid secretion is regulated by hormonal interactions among the hypothalamus, pituitary, and adrenal cortex (HPA). The synthesis and
openaire +1 more source
Glucocorticoids are essential for life. They influencing glucose metabolism, lipid metabolism, immune function, electrolyte and fluid homeostasis, development, the central nervous system, and the adrenal medulla. Glucocorticoid secretion is regulated by hormonal interactions among the hypothalamus, pituitary, and adrenal cortex (HPA). The synthesis and
openaire +1 more source
Comprehensive Physiology, 2015
The hypothalamic-pituitary-adrenal (HPA) axis regulates circulating levels of glucocorticoid hormones, and is the major neuroendocrine system in mammals that provides a rapid response and defense against stress. Under basal (i.e., unstressed) conditions, glucocorticoids are released with a pronounced circadian rhythm, characterized by peak levels of ...
Spiga, Francesca +3 more
openaire +1 more source
The hypothalamic-pituitary-adrenal (HPA) axis regulates circulating levels of glucocorticoid hormones, and is the major neuroendocrine system in mammals that provides a rapid response and defense against stress. Under basal (i.e., unstressed) conditions, glucocorticoids are released with a pronounced circadian rhythm, characterized by peak levels of ...
Spiga, Francesca +3 more
openaire +1 more source
Cytokines and HPA Axis Regulation
2003Compelling data has been amassed indicating that soluble factors, or cytokines, from the immune system can have profound effects on the neuroendocrine system, in particular the hypothalamic-pituitary-adrenal (HPA) axis. HPA activation by cytokines, in turn, has been found to play a critical role in restraining and shaping immune responses.
Marni N. Silverman +2 more
openaire +1 more source
Physiology and Pathophysiology of the HPA Axis
2010The corticotrophin releasing hormone (CRH), the main hypothalamic regulator of adrenocorticotropic hormone (ACTH) secretion, is mainly synthesized in the parvocellular, but also in the magnocellular neurons, of the paraventricular nucleus (PVN). CRH neurons of the PVN receive adrenergic afferent from nucleus tractus solitarius, locus coeruleus, and ...
Margaret Castro +3 more
openaire +1 more source
The HPA Axis and Depressive Disorders
1993During the past two decades, various abnormalities of hypothalamicpituitary-adrenocortical (HPA) axis function have been described in patients with depressive illness. Abnormalities were initially observed at the most peripheral level, i.e., urinary excretion of cortisol metabolites, but the development of reliable assays for the direct measurement of ...
openaire +1 more source
The etiology of poststroke-depression: a hypothesis involving HPA axis
Biomedicine and Pharmacotherapy, 2022Fenghua Fu, Ce Zhang
exaly