Results 21 to 30 of about 66,213 (258)
BMC Psychology, 2020 Background Urbanization is steadily increasing worldwide. Previous research indicated a higher incidence of mental health problems in more urban areas, however, very little is known regarding potential mechanisms underlying this association.
B. E. Evans +5 more
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Pharmaceuticals, 2022 Post-traumatic stress disorder (PTSD) occurs after exposure to traumatic events and is characterized by overwhelming fear and anxiety. Disturbances in the hypothalamic–pituitary–adrenal (HPA) axis are involved in the pathogenesis of mood disorders ...
Mudan Cai, Hee Ra Park, Eun Jin Yang
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Scientific Reports, 2019 The hypothalamic-pituitary-adrenal (HPA) axis orchestrates the physiological response to unpredictable acute stressors. Moreover, the HPA axis exhibits prominent circadian activity and synchronizes peripheral circadian clocks to daily environmental ...
Rohit Rao, Ioannis P. Androulakis
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Frontiers in Endocrinology, 2019 The study of the mechanisms underlying the increased vulnerability of the individual to stressful environmental factors in different age periods is of great relevance for prevention and effective treatment of stress-dependent diseases that are widespread
Nadezhda Goncharova +3 more
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Acta Psychologica, 2023 Psychopathic personality traits have been linked to low physiological arousal, particularly among high risk and forensic samples. A core indicator of physiological arousal is the activity of the hypothalamic-pituitary-adrenal (HPA) axis; however ...
Belma Isakovic +7 more
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Hypothalamic-Pituitary-Adrenal (HPA) axis [PDF]
, 2018 Increased adrenocortical secretion of hormones, primarily cortisol in depression, is one of the most consistent findings in neuropsychiatry. The maintenance of the internal homeostatic state of an individual is facilitated by the ability to circulate glucocorticoids to exert negative feedback on the secretion of hypothalamic-pituitary-adrenal (HPA ...
Young, Allan H., Juruena, Mario F.
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HPA axis participates in the osteoporosis symptoms of Parkinson's disease
生物医学转化, 2023 Parkinson's disease (PD) is considered as an independent risk factor of osteoporosis, which reveals a common pathology within the two disorders. The dysfunction of hypothalamic-pituitary-adrenal axis (HPA axis), which has been frequently reported in PD ...
Yang Chunying +5 more
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Frontiers in Neuroscience, 2021 The hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis caused by stress will inevitably disrupt the homeostasis of the neuroendocrine system and damage physiological functions.
Yu Wang +6 more
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The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
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PLoS ONE, 2021 BackgroundEarly life exposure to adverse environments, and maternal stress in particular, has been shown to increase risk for metabolic diseases and neurobehavioral disorders.
Johanna R Jahnke +3 more
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