Results 141 to 150 of about 13,686 (217)

EP300 confers protection against acute pancreatitis via acetylating HSF1 and promoting PRKN-mediated mitophagy in pancreatic acinar cells. [PDF]

Cell Commun Signal
Zhu L, Qi Z, Fan Y, Tan S, Chen H, Liu K, Zhang H, Wang K, Wang N.   +8 more
europepmc   +1 more source

Discovery of Thermal Sensitizers That Inhibit Heat-Induced SAFB Granule Formation. [PDF]

J Med Chem
Furutani Y, Shimasaki N, Yamada R, Ohtsuki T, Watanabe K.   +4 more
europepmc   +1 more source

Activation of the heat shock response as a therapeutic strategy for tau toxicity

Disease Models & Mechanisms
Taylor R. Stanley, Elizabeth M. Otero, Amy L. Knight, Aleen D. Saxton, Xinxing Ding, Melissa Borgen, Brian C. Kraemer, Karen S. Kim Guisbert, Eric Guisbert   +8 more
doaj   +1 more source

<i>ACTA2</i> Pathogenic Variants Activating Heat Shock Factor 1 and Increasing Cholesterol Biosynthesis in Smooth Muscle Cells Predispose to Early Onset Atherosclerosis. [PDF]

Circ Genom Precis Med
Boerio ML, Chattopadhyay A, Duan XY, Karla A, Calderon Martinez E, Pinard A, Morse AK, Reddy D, Dharma S, Velasco-Torrez W, Marcadier J, Prakash SK, Shalhub S, De Backer J, Jeremy R, Morris SA, Yetman AT, Braverman AC, Milewicz DM.   +18 more
europepmc   +1 more source

Dual inhibition of mTOR and HSP90 enhances cisplatin efficacy and overcomes resistance in ovarian cancer. [PDF]

Cell Death Dis
Lombardi R, Addi L, Pucci B, Bruzzese F, Sonego M, Nespolo A, Roca MS, Iannelli F, Alfano L, Capone F, Di Gennaro E, Baldassarre G, Budillon A.   +12 more
europepmc   +1 more source

Skeletal Muscle HSF1 Alleviates Age-Associated Sarcopenia and Mitochondrial Function Decline via SIRT3-PGC1α Axis. [PDF]

Adv Sci (Weinh)
Zhang J, Hu M, Wu X, Guo M, Ma Y, Qiu J, Wang S, Cao Y, Zhong Y, Chen F, Wang Y, Wei W, Lu Y, Zhang Y, Xiao J, Gan Z, Hu C, Ma X, Xu L.   +18 more
europepmc   +1 more source

Notch-1 in macrophages promoted the ischemia-reperfusion via modulating EZH2/HSF1/BRD4/SIRPα/SHP2 induced ROS and apoptosis in cardiomyocyte. [PDF]

Sci Rep
Tong C, Zhang J, Zuo Y, Yu X, Zang S, Liu S.   +5 more
europepmc   +1 more source

Celastrol Activates HSF1 to Enhance Regulatory T Cells Function and Ameliorate Intestinal Inflammation. [PDF]

Biomolecules
Alula KM, Collins CB, Nguyen TT, Aherne CM, Jedlicka P, de Zoeten EF.   +5 more
europepmc   +1 more source

Transcriptional responses to proteotoxic stressors are profoundly diverse and tissue-specific. [PDF]

Cell Stress Chaperones
Rabenius A, Salim I, Lindström H, Pak A, Aktay S, Vihervaara A.   +5 more
europepmc   +1 more source

Lactobacillus paracasei L9 Ameliorates Pulmonary Fibrosis in Aged Mice via Gut-Lung Axis-Mediated Regulation of Immune Cell Migration. [PDF]

Aging Cell
Bi R, Zhang Y, Zhang W, Shi C, Qiao Z, Quan R, Sun Y, Chen J, Wang R, Ren F, Li Y.   +10 more
europepmc   +1 more source