SUMOylation is not a prerequisite for HSF1’s role in stress protection and transactivation
Targeting tumor proteostasis has emerged as a promising strategy in anticancer therapy, particularly through Hsp90 inhibition, which has shown clinical potential.
Miroslav Bardelcik +5 more
doaj +1 more source
HSF1 modulates lipid metabolism and ferroptosis in sarcopenia: a novel diagnostic biomarker and therapeutic target. [PDF]
Cheng D +5 more
europepmc +1 more source
Functional interplay between heat shock protein 90 (HSP90) and heat shock factors (HSFs). [PDF]
Chakraborty A +2 more
europepmc +1 more source
Heat shock transcription factors in development and disease. [PDF]
Smith RS, Mendillo ML.
europepmc +1 more source
Regulation of heat shock factor 1 (HSF1)
Heat shock and other proteotoxic stresses trigger the activation of a heat shock transcription factor, Heat Shock Factor 1 (HSF1) in vertebrates, which binds to promoters of heat shock or stress protein (Hsp) genes and enhances transcription from these ...
Zou, Jiangying
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HSF1 and YTHDC1 enhance DNA repair under heat stress by promoting repair-associated gene expression. [PDF]
Ding W +6 more
europepmc +1 more source
OptoChaperone─A Biohybrid Tool for Regulating Protein Condensates in Cells and In Vitro. [PDF]
Tuan DT +13 more
europepmc +1 more source
Heat shock factor regulation of antimicrobial peptides expression suggests a conserved defense mechanism induced by febrile temperature in arthropods. [PDF]
Xiao B +5 more
europepmc +1 more source
In Silico Perturbation Identifies Transcription Factors as Protective Targets in HSPCs After Irradiation. [PDF]
Tao Z +13 more
europepmc +1 more source

