Results 111 to 120 of about 29,265 (267)

Heat shock proteins in the assessment of the course and prognosis of heart failure with preserved ejection fraction

Российский кардиологический журнал
Aim. To analyze the relationship between the concentrations of circulating heat shock proteins (HSP): HSP27, HSP70 and cardiovascular HSP (cvHSP) with the course of heart failure with preserved ejection fraction (HFpEF) and the outcomes of acute ...
Yu. S. Timofeev, T. Yu. Vedenikin, A. R. Afaunova, R. A. Zamyatin, V. A. Metelskaya, O. N. Dzhioeva, A. A. Ivanova, E. A. Neshkova, M. S. Pokrovskaya, O. M. Drapkina   +9 more
doaj   +1 more source

Prevalence of anti-Hsp27 antibodies and their relation to antisperm antibodies in infertile patients [PDF]

Pharmacia
Serum antibodies against the small heat shock protein Hsp27 (HspB1) have been associated with certain diseases but have not been studied in infertility.
Katerina Kavaldzhieva, Dimitrina Dimitrova-Dikanarova, Anton Kolarov, Desislav Dinev, Vladislav Lazarov, Nikola Mladenov   +5 more
doaj   +3 more sources

PPAR-alpha: a novel target in pancreatic cancer [PDF]

, 2015
Background: Current targeted therapies in pancreatic cancer have been ineffective. The tumor stroma, including intra- and peri-tumoral inflammation and fibrosis, is increasingly implicated in pancreatic cancer.
Hua, Alexander Mach
core   +1 more source

Cytokine-associated drug toxicity in human hepatocytes is associated signaling network dysregulation [PDF]

, 2009
Refer to Web version on PubMed Central for supplementary material.Idiosyncratic drug hepatotoxicity is a major problem in pharmaceutical development due to poor prediction capability of standard preclinical toxicity assessments and limited knowledge of ...
Ballif, Bart S. Hendriks, Benjamin D. Cosgrove, Bylesjö, Chokki, Clayton, Cosgrove, Cosgrove, Deng, Deng, Deng, Douglas A. Lauffenburger, Fielden, Ganey, Gaudet, Geladi, Gunawan, Hatano, Hotamisligil, Janes, Janes, Janes, Janes, Kaplowitz, Kaplowitz, Kemp, Kim, Kolls, Kumar, Kumar, Le, Lee, Leonidas G. Alexopoulos, Linda G. Griffith, Malhi, McCubrey, Miller-Jensen, Ono, Peter K. Sorger, Saez-Rodriguez, Sarbassov, Schwabe, Shaw, Ta-chun Hang, Tacke, Tukov, Wajant, Wold, Xu, Xu, Yuan   +50 more
core   +1 more source

Dioscin facilitates ROS-induced apoptosis via the p38-MAPK/HSP27-mediated pathways in lung squamous cell carcinoma [PDF]

, 2020
Yinan Yao, Luyun Cui, Jiani Ye, Guangdie Yang, Guohua Lu, Xiaomei Fang, Zhu Zeng, Jianying Zhou   +7 more
openalex   +1 more source

The Effects of Heat Shock Proteins on Delivery of HIV-1 Nef Antigen in Mammalian Cells

Vaccine Research, 2020
Introduction: Vaccine design is mainly considered as a therapeutic strategy to elicit HIV-specific immunity. DNA vaccines encoding an antigen and also an adjuvant can induce an effective adaptive immunity. Due to having numerous roles in viral infection,
Alireza Milani, Fatemeh Rouhollah, Maryam Naseroleslami, Azam Bolhassani   +3 more
doaj  

Autophagy-related gene 7 is downstream of heat shock protein 27 in the regulation of eye morphology, polyglutamine toxicity, and lifespan in Drosophila

Journal of Biomedical Science, 2012
Background Autophagy and molecular chaperones both regulate protein homeostasis and maintain important physiological functions. Atg7 (autophagy-related gene 7) and Hsp27 (heat shock protein 27) are involved in the regulation of neurodegeneration and ...
Chen Shih-Fen, Kang Ming-Lun, Chen Yi-Chun, Tang Hong-Wen, Huang Cheng-Wen, Li Wan-Hua, Lin Chun-Pu, Wang Chao-Yung, Wang Pei-Yu, Chen Guang-Chao, Wang Horng-Dar   +10 more
doaj   +1 more source

Extracellular Release and Signaling by Heat Shock Protein 27: Role in Modifying Vascular Inflammation

Frontiers in Immunology, 2016
Heat shock protein 27 (HSP27) is traditionally viewed as an intra-cellular chaperone protein with anti-apoptotic properties. However, recent data indicate that a number of heat shock proteins, including HSP27, are also found in the extra-cellular space ...
Zarah Batulan, Vivek Krishna Pulakazhi Venu, Yumei Li, Yumei Li, Geremy Koumbadinga, Daiana Gisela Alvarez-Olmedo, Chunhua Shi, Edward R. O'Brien   +7 more
doaj   +1 more source

Heat-shock pretreatment inhibits sorbitol-induced apoptosis in K562, U937 and HeLa cells. [PDF]

, 2009
The aim of this study was to determine whether heat-shock pretreatment exerted a protective effect against sorbitol-induced apoptotic cell death in K562, U937 and HeLa cell lines and whether such protection was associated with a decreased cytochrome c
Aventaggiato, Michele, De Martino, Luisa, Di Stefano, Carla, Fiorito, Filomena, Indelicato, Manuela, Marfe, Gabriella, Pucci, Bruna, Russo, Matteo A., Tafani, Marco   +8 more
core   +1 more source

The expression of heat shock proteins 27 and 105 in squamous cell carcinoma of the tongue and relationship with clinicopathological index [PDF]

, 2011
Introduction: In oral cavity, the tongue is the most common site prone to development of squamous cell carcinoma (SCC). Considering malignant transformation as a cellular stress, the expression of heat shock proteins (HSPs) may be affected in this ...
Anvari, Kazem, Babakoohi, Shahab, Firooz, Alireza, Khageh Ahmady, Saeedeh, Marouzi, Parviz, Memar, Bahram, Mohtasham, Nooshin, Montaser Kouhsari, Laleh, Pazoki Toroudi, Hamidreza, Rahpeyma, Amin, Salehinejad, Jahanshah   +10 more
core   +1 more source