Results 181 to 190 of about 3,351,166 (211)

Tissue-Specific Posttranslational Modification of the Small Heat Shock Protein HSP27 inDrosophila

Experimental Cell Research, 1996
Drosophila sHSPs (small heat shock proteins) are expressed in the absence of stress in specific regions of the central nervous system and in gonads of young adults flies. In these two organs, the sHSPs show a cell-specific and developmental stage-specific pattern of expression suggesting distinct regulation and function(s) of each individual sHSP (R ...
R, Marin, J, Landry, R M, Tanguay
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Small Heat Shock Proteins HSP27 and αB-Crystallin: Cytoprotective and Oncogenic Functions

Antioxidants & Redox Signaling, 2005
Heat shock protein-27 (HSP27) and alphaB-crystallin are ubiquitous small heat shock proteins whose expression is induced in response to a wide variety of physiological and environmental insults. They allow the cells to survive in otherwise lethal conditions.
Arnaud, Parcellier, Elise, Schmitt, Mathilde, Brunet, Arlette, Hammann, Eric, Solary, Carmen, Garrido   +5 more
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Heat Shock Proteins Hsp70 and Hsp27 and Neural Cellular Protection

2008
Heat shock proteins (Hsps) are expressed throughout the body. In the brain, the 27,kDa Hsp, Hsp27, and the 71–72,kDa Hsp, Hsp70, are expressed and can be protective against many stressors. Following cellular stress and injury including inflammation, ischemia, and seizures, Hsp27 and Hsp70 are induced to high levels and can protect cells from further ...
Tracy S. Voegeli, Amanda J. Wintink, R. William Currie   +2 more
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Endoplasmic reticulum stress induces the phosphorylation of small heat shock protein, Hsp27

Journal of Cellular Biochemistry, 2005
AbstractThere are several reports describing participation of small heat shock proteins (sHsps) in cellular protein quality control. In this study, we estimated the endoplasmic reticulum (ER) stress‐induced response of Hsp27 and αB‐crystallin in mammalian cells.
Hidenori, Ito, Ikuko, Iwamoto, Yutaka, Inaguma, Takenori, Takizawa, Koh-ichi, Nagata, Tomiko, Asano, Kanefusa, Kato   +6 more
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Heat-shock-protein-27(HSP27) expression in ovarian carcinoma: Relation in response to chemotherapy and prognosis

International Journal of Cancer, 1999
Heat-shock protein 27 (hsp27) is one of the small heat-shock proteins. Its expression in ovarian- and breast-cancer cell lines has been associated with resistance to cisplatin and doxorubicin. In addition, hsp27 expression appears to facilitate cellular growth, differentiation and motility.
Arts, HJG, Hollema, H, Lemstra, W, Willemse, PHB, De Vries, EGE, Kampinga, HH, Van der Zee, AGJ   +6 more
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Developmentally regulated gene expression of the small heat shock protein Hsp27 in zebrafish embryos

Gene Expression Patterns, 2006
Mammalian small heat shock proteins including Hsp27 and alpha-B crystallin are constitutively expressed in various adult and embryonic tissues including skeletal and cardiac muscle. However, the function of these proteins during embryonic development is not understood, and information on their expression during the earliest stages of development is ...
L, Mao, E A, Shelden
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Differential expression of heat shock protein HSP27 in human neurons and glial cells in culture

Journal of Neuroscience Research, 1995
AbstractHSP27 expression was investigated in cultured neurons and glial cells isolated from fetal human brains using immunoblotting and immunocytochemistry. Under unstressed conditions, HSP27 was identified at a high level in astrocytes (>99%), at a low level in neurons (7%), and at a minimally detectable level in microglia (<1%), whereas it was ...
J I, Satoh, S U, Kim
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Sudden infant death syndrome: no significant expression of heat-shock proteins (HSP27, HSP70)

Forensic Science, Medicine, and Pathology, 2015
In industrialized countries, sudden infant death is the most common cause of death in young children. Although prone sleeping position is a well-known risk factor, hyperthermia might also be important. Pathognomonic findings of premortem hyperthermia do not exist.
Elke, Doberentz, Sarah, Führing, Burkhard, Madea   +2 more
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Differential Expression of Small Heat Shock Protein 27 (Hsp27) in Ataxia telangiectasia Brains

Neurochemical Research, 2009
Ataxia telangiectasia (A-T) is a progressive neurodegenerative disorder caused by disruption of the gene, ataxia telangiectasia mutated (ATM). Present study was aimed at identifying proteins that are present in abnormal levels in A-T brain that may identify alternative targets for therapeutic interventions.
Wenqiang, Chen, Salomon, Kuizon, Bair L, Chiou, David C, Bolton, Raju K, Pullarkat, Mohammed A, Junaid   +5 more
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Subcorneal colocalization of the small heat shock protein, hsp27, with keratins and proteins of the cornified cell envelope

British Journal of Dermatology, 2002
hsp27 is a member of the small heat shock protein family. Its expression in epidermal keratinocytes in situ and in tissue culture correlates with differentiation. Experimental evidence points to the fact that hsp27 is a molecular chaperone and is involved in the regulation of cell growth and differentiation.To investigate whether epidermal hsp27 ...
C, Jonak, G, Klosner, C, Kokesch, D, FOdinger, H, HOnigsmann, F, Trautinger   +5 more
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