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Angewandte Chemie International Edition, 2016
AbstractNon‐enzymatic posttranslational modifications (nPTMs) affect at least ∼30 % of human proteins, but our understanding of their impact on protein structure and function is limited. Studies of nPTMs are difficult because many modifications are not included in common chemical libraries or protein expression systems and should be introduced site ...
Maria Matveenko +3 more
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AbstractNon‐enzymatic posttranslational modifications (nPTMs) affect at least ∼30 % of human proteins, but our understanding of their impact on protein structure and function is limited. Studies of nPTMs are difficult because many modifications are not included in common chemical libraries or protein expression systems and should be introduced site ...
Maria Matveenko +3 more
openaire +2 more sources
Serological detection of heat shock protein hsp27 in normal and breast cancer patients.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998Heat shock protein Mr 27,000 (hsp27) is found in many human breast cancer cells and tissues; its expression is associated with the presence of estrogen receptors, lower cell proliferation, and resistance to certain chemotherapies. The purpose of this study was to assess whether hsp27 may be present in sera from women with primary breast cancer and to ...
Fanelli, Mariel A. +4 more
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Role of Heat Shock Protein 27 (HSP27) in the Pathogenesis of Neurodegenerative Diseases
2012Introduction: Many neurodegenerative diseases are characterized by neuronal inclusion bodies that share common co-localizing proteins, including chaperone proteins like heat shock protein 27 (HSP27). Although HSP27 has been extensively investigated in vivo or in vitro with regard to normal protein homeostasis, its role in the pathogenesis of ...
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Role of heat shock protein in myeloproliferative neoplasms : involvement of HSP27 in myelofibrosis
2017La myélofibrose (MF) est la plus agressive des néoplasies myéloprolifératives (NMP). Elle porte à elle seule le plus mauvais pronostic pour les patients puisqu’elle s’accompagne d’une fibrose de la moelle osseuse évoluant vers une insuffisance médullaire.
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