Results 161 to 170 of about 3,351,166 (211)

Discovery of a Small-Molecule Inhibitor Targeting the ELF3-HSP27 Interaction to Suppress Breast Cancer Progression. [PDF]

Pharmaceuticals (Basel)
Liu Y, Jung S, Hwang SY, Jo H, Bang Y, Lee Y, Shin JH, Na Y, Kwon Y.   +8 more
europepmc   +1 more source

Baicalin protects against heat-induced multiorgan dysfunction <i>via</i> organ-specific protein modulation: integrative <i>in silico</i> and <i>in vivo</i> evidence. [PDF]

RSC Adv
Kumari A, Tufail A, Abdellattif MH, Dubey A, Sinha RK.   +4 more
europepmc   +1 more source

Discovery of novel peptidomimetics against HSP90-HOP interactions towards improved cancer therapeutics using machine learning strategies. [PDF]

Front Bioinform
Perumal S, Karuppasamy R.
europepmc   +1 more source

Blood-Brain Barrier (BBB)-Penetrable Androgen Receptor (AR) Degrader as a Potential Therapeutic Agent for Glioblastoma. [PDF]

ACS Pharmacol Transl Sci
Zhao X, Li Y, Martin WR, Salem F, Korem R, Bolbol S, Worden G, Sajid M, Al-Rousan A, Wilt B, Zhang W, Turchyn L, Hubert C, Ning L, Lathia JD, Zhou A, Su B.   +16 more
europepmc   +1 more source

Post-translational modifications in heat stress-related diseases. [PDF]

Front Mol Biosci
Cui Q, Jia K, Li F, Zheng J, Wang F.
europepmc   +1 more source

The role of heat shock proteins Hsp70 and Hsp27 in cellular protection of the central nervous system

International Journal of Hyperthermia, 2005
Heat shock proteins (Hsps) are highly conserved and under physiological conditions act as molecular chaperones and/or have anti-apoptotic activities. Expression in the brain of two heat shock proteins, the70 kDa Hsp (Hsp70) and the 27 kDa Hsp (Hsp27), is notable because both proteins are highly inducible in glial cells and neurons following a wide ...
Tamara B. Franklin, A -P Arrigo, R W Currie   +2 more
exaly   +5 more sources

Recruitment of phosphorylated small heat shock protein Hsp27 to nuclear speckles without stress [PDF]

Experimental Cell Research, 2007
During stress, the mammalian small heat shock protein Hsp27 enters cell nuclei. The present study examines the requirements for entry of Hsp27 into nuclei of normal rat kidney (NRK) renal epithelial cells, and for its interactions with specific nuclear structures.
Bryantsev, A.L, Chechenova, M.B, Shelden, E.A   +2 more
exaly   +5 more sources

The Effect of Oxidized Dopamine on the Structure and Molecular Chaperone Function of the Small Heat-Shock Proteins, αB-Crystallin and Hsp27

International Journal of Molecular Sciences, 2021
Oxidation of the neurotransmitter, dopamine (DA), is a pathological hallmark of Parkinson’s disease (PD). Oxidized DA forms adducts with proteins which can alter their functionality.
Thomas Preiss, Dean L Pountney, John Carver   +2 more
exaly   +2 more sources

Heat shock proteins Hsp27 and Hsp32 localize to synaptic sites in the rat cerebellum following hyperthermia [PDF]

Molecular Brain Research, 2000
Stressful stimuli activate the heat shock (stress) response in which a set of heat shock proteins (hsps) is induced, which play roles in cellular repair and protective mechanisms.
Ian R Brown, David A. Bechtold
exaly   +5 more sources