Results 1 to 10 of about 40,084 (196)

Aberrant mitochondrial hsp60 expression affects mitochondria homeostasis and results in muscle dystrophy and premature death [PDF]

Cell Death and Disease
Heat shock protein 60 (HSP60) plays a vital role in maintaining mitochondrial homeostasis and essential functions and requires ATP for its assembly into chaperone complexes.
Tsung-Hsien Chen, Chu-Kuang Chou, Kurt Ming-Chao Lin   +2 more
doaj   +2 more sources

Wide Distribution and Specific Resistance Pattern to Third-Generation Cephalosporins of Enterobacter cloacae Complex Members in Humans and in the Environment in Guadeloupe (French West Indies)

Frontiers in Microbiology, 2021
Species belonging to Enterobacter cloacae complex have been isolated in numerous environments and samples of various origins. They are also involved in opportunistic infections in plants, animals, and humans.
Matthieu Pot, Yann Reynaud, David Couvin, Célia Ducat, Séverine Ferdinand, François Gravey, Gaëlle Gruel, François Guérin, François Guérin, Edith Malpote, Sébastien Breurec, Sébastien Breurec, Sébastien Breurec, Antoine Talarmin, Stéphanie Guyomard-Rabenirina   +14 more
doaj   +1 more source

HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue

Molecular Metabolism, 2021
Objective: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60.
Robert Hauffe, Michaela Rath, Mareike Schell, Katrin Ritter, Kai Kappert, Stefanie Deubel, Christiane Ott, Markus Jähnert, Wenke Jonas, Annette Schürmann, André Kleinridders   +10 more
doaj   +1 more source

HSP60 as a target of anti-ergotypic regulatory T cells. [PDF]

PLoS ONE, 2008
The 60 kDa heat shock protein (HSP60) has been reported to influence T-cell responses in two ways: as a ligand of toll-like receptor 2 signalling and as an antigen.
Francisco J Quintana, Avishai Mimran, Pnina Carmi, Felix Mor, Irun R Cohen   +4 more
doaj   +1 more source

Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C

mBio, 2022
The maintenance of viral protein homeostasis depends on the machinery of the infected host cells, giving us an insight into the interplay between host and virus.
Jianli Tang, Sahibzada Waheed Abdullah, Pinghua Li, Jin'en Wu, Chenchen Pei, Suyu Mu, Yunlu Wang, Shiqi Sun, Huichen Guo   +8 more
doaj   +1 more source

Heat shock protein 60 expression and localisation in different tissues and testis development of male cattle (cattle-yak and yak)

Folia Morphologica, 2021
BACKGROUND: Heat shock protein 60 (Hsp60) play important roles in protecting testicular development and production of sperms. This study was conducted to investigate Hsp60 gene expression and localisation in testicular development to ascertain its ...
S. Zou, P. Liu, S. Yu, Y. Cui, J. He, S. Y. Afedo, H. Zhang, R. Niayale, K. Zhao   +8 more
doaj   +1 more source

Draft genome sequence of Enterobacter chengduensis ECC445, isolated from fresh water in the West Indies

BMC Genomic Data, 2023
Objectives The Enterobacter cloacae complex is considered an important opportunistic pathogen. It comprises many members that remain difficult to delineate by phenotypic approaches.
Matthieu Pot, Célia Ducat, Yann Reynaud, David Couvin, Séverine Ferdinand, Sébastien Breurec, Antoine Talarmin, Stéphanie Guyomard-Rabenirina   +7 more
doaj   +1 more source

Increased levels of IgG antibodies against human HSP60 in patients with spondyloarthritis. [PDF]

PLoS ONE, 2013
Spondyloarthritis (SpA) comprises a heterogeneous group of inflammatory diseases, with strong association to human leukocyte antigen (HLA)-B27. A triggering bacterial infection has been considered as the cause of SpA, and bacterial heat shock protein ...
Astrid Hjelholt, Thomas Carlsen, Bent Deleuran, Anne Grethe Jurik, Berit Schiøttz-Christensen, Gunna Christiansen, Svend Birkelund   +6 more
doaj   +1 more source

Djhsp60 Is Required for Planarian Regeneration and Homeostasis

Biomolecules, 2022
HSP60, a well-known mitochondrial chaperone, is essential for mitochondrial homeostasis. HSP60 deficiency causes dysfunction of the mitochondria and is lethal to animal survival.
Kexue Ma, Rui Li, Gege Song, Fangying Guo, Meng Wu, Qiong Lu, Xinwei Li, Guangwen Chen   +7 more
doaj   +1 more source

HSP60 knockdown exerts differential response in endothelial cells and monocyte derived macrophages during atherogenic transformation

Scientific Reports, 2021
Ectopic expression of HSP60 in vascular cells is known to activate auto-immune response that is critical to atherogenic initiation. However, the pathogenic relevance of the aberrant HSP60 upregulation in intracellular signaling pathways associated with ...
Kavita Shirsath, Apeksha Joshi, Aliasgar Vohra, Ranjitsinh Devkar   +3 more
doaj   +1 more source