Results 61 to 70 of about 39,355 (215)

Heat shock protein 60 (HSP60) modulates adiponectin signaling by stabilizing adiponectin receptor

Cell Communication and Signaling, 2020
Adiponectin, an adipokine produced and secreted by adipocytes, is involved in regulating the development and progression of insulin resistance, diabetes, and diabetic complications.
Deling Zhang, Hua Liu, Yemin Zhang, Junfeng Li, Yalin Fu, Yuyang Zheng, Jie Wu, Mingke Ma, Zhongyuan Wen, Changhua Wang   +9 more
doaj   +1 more source

Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]

, 2001
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Berencsi, Klára, Boda, Krisztina, Burián, Katalin, Duba, Jenő, Endrész, Valéria, Füst, György, Gönczöl, Éva, Horváth, Laura, Kis, Zoltán, Prohászka, Zoltán, Romics, László, Virók, Dezső   +11 more
core   +1 more source

Microfluidic Intracytoplasmic Sperm Injection (MICSI): A Novel Platform for Sperm Isolation, Selection, and Injection Into Oocytes

Andrology, EarlyView.
ABSTRACT Background Infertility is a pressing global health concern, affecting one in six couples worldwide. The failure rate for assisted reproductive technologies (ART) cycles remains at approximately 78%, with limited improvements often attributed to a lack of technological innovation.
Mehran Dabiri, Dale Mark Goss, Steven Alexander Vasilescu, Majid Ebrahimi Warkiani   +3 more
wiley   +1 more source

The Challenging Riddle about the Janus-Type Role of Hsp60 and Related Extracellular Vesicles and miRNAs in Carcinogenesis and the Promises of Its Solution

Applied Sciences, 2021
Hsp60 is one of the most ancient and evolutionarily conserved members of the chaperoning system. It typically resides within mitochondria, in which it contributes to maintaining the organelle’s proteome integrity and homeostasis.
Sabrina David, Alessandra Maria Vitale, Alberto Fucarino, Federica Scalia, Giuseppe Vergilio, Everly Conway de Macario, Alberto J. L. Macario, Celeste Caruso Bavisotto, Alessandro Pitruzzella   +8 more
doaj   +1 more source

MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs [PDF]

, 2016
Medulloblastoma (MB) is the most common malignant brain tumor of pediatric age and is characterized by cells expressing stem, astroglial, and neuronal markers.
Alfano, Vincenzo, Besharat, ZEIN MERSINI, Carai, Andrea, Catanzaro, Giuseppina, Ferretti, Elisabetta, Garg, Neha, Locatelli, Franco, Mastronuzzi, Angela, Miele, Evelina, Pieroni, Luisa, Po, Agnese, Ronci, Maurizio, Screpanti, Isabella, Urbani, Andrea   +13 more
core   +4 more sources

HSP101‐encoding NEO‐TETRAPLOID RICE FERTILITY GENE 1 regulates tapetum development through interaction with SAPK2 in polyploid rice

Journal of Integrative Plant Biology, EarlyView.
In neo‐tetraploid rice, the NTRF1–SAPK2 heat shock protein–kinase module coordinates abscisic acid signaling with reactive oxygen species homeostasis to ensure timely tapetal programmed cell death and subsequent pollen maturation, providing a resource for the genetic improvement of polyploid rice.
Lichong Cao, Weicong Huang, Hang Yu, Sanglin Liu, Jianmin Yin, Zijun Lu, Jinwen Wu, Xiangdong Liu   +7 more
wiley   +1 more source

Hsp60 and human aging: Les liaisons dangereuses  [PDF]

Frontiers in Bioscience, 2013
Stressors can cause abnormal intracellular accumulation of Hsp60 and its localization in extramitochondrial sites, secretion, and circulation, with immune system activation. Dysfunction of chaperones associated with their quantitative and qualitative decline with aging (chaperonopathies of aging) characterizes senescence and is a potential causal ...
CAPPELLO, Francesco, Conway De Macario, E, MARINO GAMMAZZA, Antonella, BONAVENTURA, Giuseppe, CARINI, Francesco, Czarnecka, AM, FARINA, Felicia, ZUMMO, Giovanni, Macario, AJL   +8 more
openaire   +3 more sources

The dissociation of the Hsp60/pro-Caspase-3 complex by bis(pyridyl)oxadiazole copper complex (CubipyOXA) leads to cell death in NCI-H292 cancer cells [PDF]

, 2017
Cell survival and proliferation are central to carcinogenesis, involving various mechanisms among which those that impede apoptosis are important. In this, the role of the molecular chaperone Hsp60 is unclear since it has been reported that it can be ...
Barone, G., Barone, R., Campanella, C., Cappello, F., Caruso Bavisotto, C., Conway de Macario, E., Giacalone, V., Lo Cascio, F., Macario, A., Marino Gammazza, A., Mocciaro, E., Nikolic, D., Pace, A., Palumbo Piccionello, A., Zummo, G.   +14 more
core   +1 more source

OsCPN10a, cooperating with OsCPN20 and OsHSP60‐3B negatively regulate ABA signaling and enhance seed storability in rice

Journal of Integrative Plant Biology, EarlyView.
Abscisic acid signaling homeostasis is essential for seed storability. The molecular chaperone OsCPN10a enhances rice seed storability by forming a trimeric chaperone complex with OsCPN20‐OsHSP60‐3B that attenuates abscisic acid signaling via direct interaction with OsPYL10‐OsABIL1, thereby maintaining starch integrity and offering a promising target ...
Sufeng Liao, Yidong Wei, Yongsheng Zhu, Kunyang Li, Ting Chen, Shuai Zhao, Fangxi Wu, Jinlan Wang, Pengbo Yu, Hongguang Xie, Liping Chen, Qiuhua Cai, Huaan Xie, Jianfu Zhang   +13 more
wiley   +1 more source

The Hsp70 and Hsp60 Chaperone Machines

Cell, 1998
B. B. thanks members of his lab and J. Reinstein for critical reading of the manuscript and C. Gassler, T. Laufen, and S. Rudiger for figure preparation. A. H. thanks Wayne Fenton for critical reading and Zhaohui Xu for figure preparation. A. H. dedicates this work to Guenter Brueckner, always an inspiration.
Bukau, Bernd, Horwich, Arthur L
openaire   +3 more sources