Results 71 to 80 of about 109,486 (229)

The Comparative Analysis of Antiviral Activity of Native and Modified Fucoidans from Brown Algae Fucus evanescens In Vitro and In Vivo

Marine Drugs, 2020
The enzymatic depolymerization of fucoidans from brown algae allowed the production of their standardized derivatives with different biological activities.
Natalya V. Krylova, Svetlana P. Ermakova, Vyacheslav F. Lavrov, Irina A. Leneva, Galina G. Kompanets, Olga V. Iunikhina, Marina N. Nosik, Linna K. Ebralidze, Irina N. Falynskova, Artem S. Silchenko, Tatyana S. Zaporozhets   +10 more
doaj   +1 more source

HSV neutralization by the microbicidal candidate C5A. [PDF]

PLoS ONE, 2011
Genital herpes is a major risk factor in acquiring human immunodeficiency virus type-1 (HIV-1) infection and is caused by both Herpes Simplex virus type 1 (HSV-1) and HSV-2.
Lot de Witte, Michael D Bobardt, Udayan Chatterji, Freek B van Loenen, Georges M G M Verjans, Teunis B H Geijtenbeek, Philippe A Gallay   +6 more
doaj   +1 more source

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells [PDF]

, 2012
In the course of primary infection with herpes simplex virus 1 (HSV-1), children with inborn errors of TLR3 immunity are prone to HSV-1 encephalitis (HSE) 1–3.
Abel, Laurent, Abhyankar, Avinash, Al-Muhsen, Saleh, Casanova, Jean-Laurent, Ciancanelli, Michael J., Daley, George Quentin, Elkabetz, Yechiel, Goldstein, Peter A., Herman, Melina, Jouanguy, Emmanuelle, Keros, Sotirios, Lafaille, Fabien G, Mostoslavsky, Gustavo, Notarangelo, Luigi D., Ordovas-Montanes, Jose Manuel, Pessach, Itai M., Plancoulaine, Sabine, Schlaeger, Thorsten M., Studer, Lorenz, Tardieu, Marc, Tu, Edmund, Ying, Shui-Wang, Zhang, Shen-Ying   +22 more
core   +1 more source

Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations

BMC Infectious Diseases, 2002
Background The thymidine kinase (tk) mutagenesis assay is often utilized to determine the frequency of herpes simplex virus (HSV) replication-mediated mutations. Using this assay, clinical and laboratory HSV-2 isolates were shown to have a 10- to 80-fold
Leary Jeffry J, Halsey Wendy M, Bartus Joan O, Wittrock Robert J, Nguyen Tammy T, Quail Matthew R, Duffy Karen E, Bacon Teresa H, Sarisky Robert T   +8 more
doaj   +1 more source

تغییرات اپیدمیولوژیHSV-1: اثر آن بر روی وقوع هرپس چشمی [PDF]

Archives of Razi Institute, 2016
HSV-1 شیوع گسترده­ای در بین جمعیت­های انسانی دارد و نتیجه آن ایجاد طیف گسترده­ای از عفونت­ها و بیماری­ها می­باشد.اگرچه،HSV-2  عامل اصلی هرپس جنسی می­باشد، هرپس جنسی ناشی از HSV-1 نیز در حال افزایش می­باشد. این مقاله تغییرات اپیدمیولوژیکی HSV-1 را که شامل
بهمن عابدی کیاسری, زهره زارع توران پشتی   +1 more
doaj   +1 more source

Pharmacomanipulation of HSV-1 induced chorioretinitis in mice [PDF]

Eye, 1997
In the von Szily mouse model, intracameral inoculation of herpes simplex virus type-1 (HSV-1) results in inflammation of the ipsilateral anterior segment with relative chorioretinal sparing and destructive contralateral chorioretinitis. We studied the effect of the systemic antiviral agent acyclovir (ACV) and anti-HSV-1 antibody therapy in this model ...
J Fletcher, A Merchant, Ramzi K. Hemady, Christopher S. Foster, C A Medina   +4 more
openaire   +3 more sources

African green monkey kidney Vero cells require de novo protein synthesis for efficient herpes simplex virus 1-dependent apoptosis [PDF]

, 2005
During HSV-1 infection, IE gene expression triggers apoptosis, but subsequent synthesis of infected cell proteins blocks apoptotic death from ensuing. This “HSV-1-dependent” apoptosis was identified in HEp-2/HeLa cells infected with wild-type HSV-1 in ...
Blaho, John A., Kraft, Rachel M., Nguyen, Marie L.   +2 more
core   +1 more source

One of the Mechanisms to Increase HSV-1 Uptake in HSV-1-Infected, Activated T Lymphocytes Is the Formation of Filopodia

Intervirology, 2015
<b><i>Objectives:</i></b> To explore the host transcription factor E2F-1 and/or any mechanisms that may support viral entry and its effect on the HSV-1 production in anti-CD3-activated Jurkat cells. <b><i>Methods:</i></b> The expressions of ICP4, HVEM and E2F-1 were studied using reverse transcription-PCR
Pornnapa Donchai, Parvapan Bhattarakosol
openaire   +3 more sources

Detection of Viruses in Dentin Caries and Necrotic Pulp Caries Using ELISA Technique in Mosul, Iraq

Medical Journal of Babylon
Background: Dental caries is a multifactorial disease that can affect human teeth, and viruses play a hidden role in forming caries cavities and dental plaque.
Enas Yaseen Shehab, Anmar A. AlTaie, Basima A. Abdullah   +2 more
doaj   +1 more source

Correction: IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

PLOS Pathogens, 2018
[This corrects the article DOI: 10.1371/journal.ppat.1004503.].
Karen E Johnson, Virginie Bottero, Stephanie Flaherty, Sujoy Dutta, Vivek Vikram Singh, Bala Chandran   +5 more
openaire   +3 more sources