Results 21 to 30 of about 34,196 (189)

Effect of HTLV-1 Infection on the Clinical Course of Patients with Rheumatoid Arthritis

Viruses, 2022
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The effects of HTLV-1 on health are not fully elucidated.
Kunihiko Umekita
doaj   +1 more source

Caracterização molecular do HTLV-1 em pacientes com paraparesia espástica tropical/mielopatia associada ao HTLV-1 em Belém, Pará Molecular characterization of HTLV-1 among patients with tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará

Revista da Sociedade Brasileira de Medicina Tropical, 2006
O presente estudo avaliou a ocorrência da infecção pelo HTLV-1 e seus subtipos em amostras de sangue de pacientes com diagnóstico clínico de paraparesia espástica tropical/mielopatia associada ao Htlv-1.
Lucinda A. Souza, Ivina G.L. Lopes, Eduardo Leitão Maia, Vânia N. Azevedo, Luiz Fernando A. Machado, Marluísa O.G. Ishak, Ricardo Ishak, Antonio Carlos R. Vallinoto   +7 more
doaj   +1 more source

Anti-HTLV-1/2 IgG Antibodies in the Breastmilk of Seropositive Mothers

Microorganisms, 2021
Background: HTLV-1/2 mother-to-child transmission (MTCT) is an important route for the maintenance of HTLV-1/2 within populations and disproportionally contributes to the burden of HTLV-1-associated diseases.
Carolina Rosadas, Timothy Woo, Jana Haddow, Aileen Rowan, Graham P. Taylor   +4 more
doaj   +1 more source

Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication [PDF]

The Journal of Immunology, 2017
Abstract Human T lymphotropic virus type 1 (HTLV-1) belongs to the deltaretrovirus family and has been linked to multiple diseases. However, the innate host defense against HTLV-1 is unclear. In this study, we report that the expression of Ku70, a known DNA sensor against DNA viruses, could be induced by HTLV-1 infection in HeLa, PMA ...
Jie Wang, Lixia Kang, Di Song, Lu Liu, Shuai Yang, Lingling Ma, Zhixiang Guo, Huaxia Ding, Hui Wang, Bo Yang   +9 more
openaire   +2 more sources

Human T-cell leukemia virus type 1 infection among Japanese immigrants and their descendants living in Southeast Brazil: A call for preventive and control responses.

PLoS Neglected Tropical Diseases, 2021
Human T-cell leukemia virus type 1 (HTLV-1) has worldwide distribution and is considered endemic in southwestern Japan. HTLV-1 infection has been associated with adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic ...
Larissa M Bandeira, Marco A M Puga, Sabrina M S Weis-Torres, Grazielli R Rezende, João A Domingos, Tayana S O Tanaka, Gabriela A Cesar, Youko Nukui, Ana C P Vicente, Jorge Casseb, Juliana Yamashiro, Aluísio C Segurado, Murilo O Saito, João R R Pinho, Rivaldo V Cunha, Osnei Okumoto, Silvia N O Uehara, Ana R C Motta-Castro   +17 more
doaj   +1 more source

Development of a Monoclonal Antibody Targeting HTLV-1 Envelope gp46 Glycoprotein and Its Application to Near-Infrared Photoimmuno-Antimicrobial Strategy

Viruses, 2022
Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus, causes adult T-cell leukemia-lymphoma, HTLV-1 associated myelopathy/tropical spastic paraparesis, and HTLV-1 uveitis.
Yasuyoshi Hatayama, Yutaro Yamaoka, Takeshi Morita, Sundararaj Stanleyraj Jeremiah, Kei Miyakawa, Mayuko Nishi, Yayoi Kimura, Makoto Mitsunaga, Tadayuki Iwase, Hirokazu Kimura, Naoki Yamamoto, Akifumi Takaori-Kondo, Hideki Hasegawa, Akihide Ryo   +13 more
doaj   +1 more source

Vertical Transmission of HTLV‐1 in HTLV‐1 Carrier Rat [PDF]

Japanese Journal of Cancer Research, 1992
A female F344 rat was injected with 2.4 × 106 MT‐2 cells intravenously at 3 and 4 weeks old, and was mated with a non‐infected male rat at the 17th week after injection, when the dam rat contained HTLV‐1 provirus in the peripheral blood mononuclear cells as determined by polymerase chain reaction.
Ami, Yoshihiro, Kushida, Shigeki, Matsumura, Masayuki, Yoshida, Yuki, Kameyama, Tsuneo, Sugiyama, Yoshihiro, Yagami, Ken‐ichi, Uchida, Masako, Uchida, Kazuhiko, Koiso, Kenkichi, Miwa, Masanao   +10 more
openaire   +2 more sources

Cellular factors involved in HTLV-1 entry and pathogenicity

Frontiers in Microbiology, 2012
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T cell leukemia (ATL) and HTLV-1–associated myelopathy and tropical spastic paraparesis (HAM/TSP).
Hiroo eHoshino
doaj   +1 more source

HAS-Flow May Be an Adequate Method for Evaluating Human T-Cell Leukemia Virus Type 1 Infected Cells in Human T-Cell Leukemia Virus Type 1-Positive Rheumatoid Arthritis Patients Receiving Antirheumatic Therapies: A Retrospective Cross-Sectional Observation Study

Viruses, 2023
The study aims to assess the usefulness of human T-cell leukemia virus type 1 (HTLV-1)-infected cell analysis using flow cytometry (HAS-Flow) as a monitoring method for adult T-cell leukemia (ATL) development in HTLV-1-positive patients with rheumatoid ...
Kunihiko Umekita, Yuki Hashikura, Akira Takaki, Masatoshi Kimura, Katsumi Kawano, Chihiro Iwao, Shunichi Miyauchi, Takeshi Kawaguchi, Motohiro Matsuda, Yayoi Hashiba, Toshihiko Hidaka   +10 more
doaj   +1 more source

Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis

Viruses, 2010
Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes both in vitro and in vivo.
Patrick L. Green, Priya Kannian
doaj   +1 more source