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Caracterização molecular do HTLV-1 em pacientes com paraparesia espástica tropical/mielopatia associada ao HTLV-1 em Belém, Pará Molecular characterization of HTLV-1 among patients with tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2006
O presente estudo avaliou a ocorrência da infecção pelo HTLV-1 e seus subtipos em amostras de sangue de pacientes com diagnóstico clínico de paraparesia espástica tropical/mielopatia associada ao Htlv-1.
Lucinda A. Souza   +7 more
doaj   +1 more source

Development of a Monoclonal Antibody Targeting HTLV-1 Envelope gp46 Glycoprotein and Its Application to Near-Infrared Photoimmuno-Antimicrobial Strategy

open access: yesViruses, 2022
Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus, causes adult T-cell leukemia-lymphoma, HTLV-1 associated myelopathy/tropical spastic paraparesis, and HTLV-1 uveitis.
Yasuyoshi Hatayama   +13 more
doaj   +1 more source

Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects. [PDF]

open access: yes, 2016
Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Blackburn, Elizabeth   +5 more
core   +3 more sources

Vertical Transmission of HTLV‐1 in HTLV‐1 Carrier Rat [PDF]

open access: yesJapanese Journal of Cancer Research, 1992
A female F344 rat was injected with 2.4 × 106 MT‐2 cells intravenously at 3 and 4 weeks old, and was mated with a non‐infected male rat at the 17th week after injection, when the dam rat contained HTLV‐1 provirus in the peripheral blood mononuclear cells as determined by polymerase chain reaction.
Ami, Yoshihiro   +10 more
openaire   +2 more sources

Cellular factors involved in HTLV-1 entry and pathogenicity

open access: yesFrontiers in Microbiology, 2012
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T cell leukemia (ATL) and HTLV-1–associated myelopathy and tropical spastic paraparesis (HAM/TSP).
Hiroo eHoshino
doaj   +1 more source

HAS-Flow May Be an Adequate Method for Evaluating Human T-Cell Leukemia Virus Type 1 Infected Cells in Human T-Cell Leukemia Virus Type 1-Positive Rheumatoid Arthritis Patients Receiving Antirheumatic Therapies: A Retrospective Cross-Sectional Observation Study

open access: yesViruses, 2023
The study aims to assess the usefulness of human T-cell leukemia virus type 1 (HTLV-1)-infected cell analysis using flow cytometry (HAS-Flow) as a monitoring method for adult T-cell leukemia (ATL) development in HTLV-1-positive patients with rheumatoid ...
Kunihiko Umekita   +10 more
doaj   +1 more source

Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance The oncogenic retrovirus human T-cell leukemia virus type 1 (HTLV-1) encodes Tax, an activator of both viral replication and cellular oncogenic pathways. Despite the potent activities of Tax, its precise roles in pathogenesis remain unclear,
Mohamed Mahgoub   +6 more
semanticscholar   +1 more source

Human T-cell leukemia virus type 1 infection among Japanese immigrants and their descendants living in Southeast Brazil: A call for preventive and control responses.

open access: yesPLoS Neglected Tropical Diseases, 2021
Human T-cell leukemia virus type 1 (HTLV-1) has worldwide distribution and is considered endemic in southwestern Japan. HTLV-1 infection has been associated with adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic ...
Larissa M Bandeira   +17 more
doaj   +1 more source

Anti-HTLV-1/2 IgG Antibodies in the Breastmilk of Seropositive Mothers

open access: yesMicroorganisms, 2021
Background: HTLV-1/2 mother-to-child transmission (MTCT) is an important route for the maintenance of HTLV-1/2 within populations and disproportionally contributes to the burden of HTLV-1-associated diseases.
Carolina Rosadas   +4 more
doaj   +1 more source

Comparative virology of HTLV-1 and HTLV-2

open access: yesRetrovirology, 2019
Human T cell leukemia virus type 1 (HTLV-1) was the first discovered human retrovirus and the etiologic agent of adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis.
Michael P Martinez   +2 more
semanticscholar   +1 more source

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