Results 11 to 20 of about 270,658 (298)
Long-Term Electrical and Mechanical Function Monitoring of a Human-on-a-Chip System. [PDF]
Adv Funct Mater, 2019 AbstractThe goal of human‐on‐a‐chip systems is to capture multiorgan complexity and predict the human response to compounds within physiologically relevant platforms. The generation and characterization of such systems is currently a focal point of research given the long‐standing inadequacies of conventional techniques for predicting human outcome ...
Oleaga C +20 more
europepmc +3 more sources
Human Organs-on-Chips for Virology [PDF]
Trends in Microbiology, 2020 While conventional in vitro culture systems and animal models have been used to study the pathogenesis of viral infections and to facilitate development of vaccines and therapeutics for viral diseases, models that can accurately recapitulate human responses to infection are still lacking.
Tang, H. +6 more
openaire +4 more sources
Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2018 Introdução: Modelos com maior capacidade preditiva e que produzam resultados a custos mais baixos e em prazos menores são necessários para o desenvolvimento de fármacos. Os sistemas microfisiológicos (SMF) que cultivam tecidos humanos em histoarquitetura
Talita Miguel Marin, Eduardo Pagani
doaj +7 more sources
Microfluidic Gut-on-a-Chip: Fundamentals and Challenges
Biosensors, 2023 The human gut is responsible for food digestion and absorption. Recently, growing evidence has shown its vital role in the proper functioning of other organs.
Dimple Palanilkunnathil Thomas +3 more
doaj +1 more source
Advances in human organoids-on-chips in biomedical research
Life Medicine, 2023 AbstractOrganoids-on-chips is opening up new frontier of research in biomedical field by combining organoids and organs-on-chips technology. The integrative technology offers great opportunities to maximize the potentials of organoids with higher fidelity, thus building advanced organ model systems in a physiologically relevant manner.
Wang, Yaqing, Qin, Jianhua
openaire +2 more sources
Organ-On-A-Chip: An Emerging Research Platform
Organogenesis, 2023 In drug development, conventional preclinical and clinical testing stages rely on cell cultures and animal experiments, but these methods may fall short of fully representing human biology.
Nithin R +4 more
doaj +1 more source
Frontiers in Toxicology, 2022 Investigating systemic toxicity in vitro is still a huge challenge. Here, a multi-organ-on-chip approach is presented as a typical case of topical exposure of oral mucosa to metals, which are known to activate the immune system and in turn may result in ...
Jasper J. Koning +8 more
doaj +1 more source
Human Nonalcoholic Steatohepatitis on a Chip
Hepatology Communications, 2021 Nonalcoholic steatohepatitis (NASH), an advanced stage of nonalcoholic fatty liver disease (NAFLD), is a rapidly growing and global health problem compounded by the current absence of specific treatments. A major limiting factor in the development of new
May S. Freag +5 more
doaj +1 more source
Materials & Design, 2018 The non-ionic surfactant, Tween 80 (T80) a material with promising applications in the pharmaceutical, cosmetic, and food industries, has been explored here for the design of novel nanostructures (NS).
Dickson Joseph +3 more
doaj +1 more source