Results 21 to 30 of about 274,463 (252)
Modeling the Effects of Protracted Cosmic Radiation in a Human Organ-on-Chip Platform. [PDF]
Adv Sci (Weinh)AbstractGalactic cosmic radiation (GCR) is one of the most serious risks posed to astronauts during missions to the Moon and Mars. Experimental models capable of recapitulating human physiology are critical to understanding the effects of radiation on human organs and developing radioprotective measures against space travel exposures.
Tavakol DN +17 more
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The three‐dimensional structure of human erythrocyte aquaporin CHIP. [PDF]
The EMBO Journal, 1994 Water-permeable membranes of several plant and mammalian tissues contain specific water channel proteins, the 'aquaporins'. The best characterized aquaporin is CHIP, a 28 kDa red blood cell channel-forming integral protein. Isolated CHIP and Escherichia coli lipids may be assembled into 2-D crystals for structural analyses.
Walz, T. +3 more
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Frontiers in Pharmacology, 2021 Current intervention strategies have not been successful in reducing the risks of adverse pregnancy complications nor maternal and fetal morbidities associated with pregnancy complications.
Esha Ganguly +6 more
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Differential Monocyte Actuation in a Three‐Organ Functional Innate Immune System‐on‐a‐Chip
Advanced Science, 2020 A functional, human, multiorgan, pumpless, immune system‐on‐a‐chip featuring recirculating THP‐1 immune cells with cardiomyocytes, skeletal muscle, and liver in separate compartments in a serum‐free medium is developed. This in vitro platform can emulate
Trevor Sasserath +10 more
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Developmentally inspired human ‘organs on chips’ [PDF]
Development, 2018 ABSTRACT Although initially developed to replace animal testing in drug development, human ‘organ on a chip’ (organ chip) microfluidic culture technology offers a new tool for studying tissue development and pathophysiology, which has brought us one step closer to carrying out human experimentation in vitro.
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Marine Drugs, 2018 Current trends in the application of nanomaterials are emerging in the nano-biotechnological sector for development of medicines. Cyanobacteria (blue-green algae) are photosynthetic prokaryotes that have applications to human health and numerous ...
Vivek K. Bajpai +6 more
doaj +1 more source
On being the right size: scaling effects in designing a human-on-a-chip [PDF]
Integrative Biology, 2013 Developing a human-on-a-chip by connecting multiple model organ systems would provide an intermediate screen for therapeutic efficacy and toxic side effects of drugs prior to conducting expensive clinical trials. However, correctly designing individual organs and scaling them relative to each other to make a functional microscale human analog is ...
Moraes, Christopher +5 more
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Toxicology Letters, 2016 Presentation for the British Pharmacological Society 'Pharmacology 2016' Meeting.https://www.bps.ac.uk/pharmacology2016Part of the Symposium 'Track 5: Organ-on-a-chip technology - the future of physiological profiling?'https://www.bps.ac.uk/pharmacology2016#Day ...
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Cystic Fibrosis Human Organs-on-a-Chip
Micromachines, 2021 Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane regulator (CFTR) gene: the gene product responsible for transporting chloride and bicarbonate ions through the apical membrane of most ...
Herbert Luke Ogden +4 more
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A systematic review with narrative synthesis on medical robotics and laboratory automation in the control of SARS-CoV-2, Ebola and H1N1 (Swine Flu) viruses [PDF]
Journal of Health and Social Sciences, 2020 Introduction: Medical robotics is a rapidly growing aspect of the modern health care landscape. The aim of this paper was to review the availability of robotic technology and laboratory automation in the control of SARS-CoV-2, Ebola and H1N1 (Swine Flu ...
Shantani KANNAN +3 more
doaj +1 more source