Results 21 to 30 of about 263,329 (257)

Chip-based liver equivalents for toxicity testing - organotypicalness versus cost-efficient high throughput [PDF]

, 2013
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Marx, Uwe, Materne, Eva-Maria, Tonevitsky, Alexander G.   +2 more
core   +1 more source

Chitosan Oligosaccharides Regulate the Occurrence and Development of Enteritis in a Human Gut-On-a-Chip

Frontiers in Cell and Developmental Biology, 2022
Past studies on the protective effects of chitosan oligosaccharides (COS) on inflammatory bowel disease (IBD) commonly rely on animal models, because traditional cell culture systems couldn’t faithfully mimic human intestinal physiology.
Bolin Jing, Bolin Jing, Kun Xia, Chen Zhang, Siming Jiao, Limeng Zhu, Jinhua Wei, Zhuo A. Wang, Nannan Chen, Pengfei Tu, Jianjun Li, Yuguang Du   +11 more
doaj   +1 more source

Fluorescent optical fiber sensors for cell viability monitoring [PDF]

, 2013
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Marx, Uwe, Rusanov, Alexander, Sakharov, Dmitry, Sergachev, Ilia, Tonevitsky, Alexander, Trushkin, Evgeny   +5 more
core   +1 more source

Organ-on-a-chip: recent breakthroughs and future prospects

BioMedical Engineering OnLine, 2020
The organ-on-a-chip (OOAC) is in the list of top 10 emerging technologies and refers to a physiological organ biomimetic system built on a microfluidic chip.
Qirui Wu, Jinfeng Liu, Xiaohong Wang, Lingyan Feng, Jinbo Wu, Xiaoli Zhu, Weijia Wen, Xiuqing Gong   +7 more
doaj   +1 more source

Organic Anion Transporting Polypeptide 2B1 in Human Fetal Membranes: A Novel Gatekeeper for Drug Transport During Pregnancy?

Frontiers in Pharmacology, 2021
Current intervention strategies have not been successful in reducing the risks of adverse pregnancy complications nor maternal and fetal morbidities associated with pregnancy complications.
Esha Ganguly, Ananth Kumar Kammala, Meagan Benson, Lauren S. Richardson, Lauren S. Richardson, Arum Han, Ramkumar Menon   +6 more
doaj   +1 more source

Towards Human on a Chip: Recent Progress and Future Perspective

Micro and Nanosystems, 2014
A system of multiple organs integrated on a single chip or human on a chip (HUC) has a great potential for drug discovery. Such a system helps to advance the fundamental understanding of diseases as well as the complex interactions between cells, tissues and organs.
Van Noort, D, Park, S, Nguyen, NT
openaire   +1 more source

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents [PDF]

, 2015
Systemic absorption and metabolism of drugs in the small intestine, metabolism by the liver as well as excretion by the kidney are key determinants of efficacy and safety for therapeutic candidates. However, these systemic responses of applied substances
Bauer, Sophie, Drewell, Christopher, Hasenberg, Tobias, Hübner, Juliane, Lauster, Roland, Lindner, Marcus, Lorenz, Alexandra K., Marx, Uwe, Maschmeyer, Ilka, Ramme, Anja P., Sambo, Naomia Sisoli, Schimek, Katharina, Sonntag, Frank, Thomas, Alexander   +13 more
core   +1 more source

Development of a novel 3D culture system for screening features of a complex implantable device for CNS repair [PDF]

, 2013
Tubular scaffolds which incorporate a variety of micro- and nanotopographies have a wide application potential in tissue engineering especially for the repair of spinal cord injury (SCI).
Bereiter-Hahn J., Casey B. G., Cavaglia M., Chary S. R., Clark P., Csaderova L., Gadegaard N., Gadegaard N., Gailit J., Gilbert R. J., Huh D., Lakatos A., Mathis O. Riehle, Mirastschijski U., Nikolaj Gadegaard, Noble M., Peter S. Donoghue, Robert P., Ruff R. L., Salem A. K., Sarkar S., Seunarine K., Sun T., Sun T., Sun T., Susan C. Barnett, Sørensen A., Sørensen A., Tao Sun, Thomson C. E., Van Harreveld A., Yamada M.   +31 more
core   +3 more sources

Differential Monocyte Actuation in a Three‐Organ Functional Innate Immune System‐on‐a‐Chip

Advanced Science, 2020
A functional, human, multiorgan, pumpless, immune system‐on‐a‐chip featuring recirculating THP‐1 immune cells with cardiomyocytes, skeletal muscle, and liver in separate compartments in a serum‐free medium is developed. This in vitro platform can emulate
Trevor Sasserath, John W. Rumsey, Christopher W. McAleer, Lee Richard Bridges, Christopher J. Long, Daniel Elbrecht, Franz Schuler, Adrian Roth, Christina Bertinetti‐LaPatki, Michael L. Shuler, James J. Hickman   +10 more
doaj   +1 more source

A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture [PDF]

, 2013
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Brincker, Sven, Busek, Mathias, Frädrich, Caroline, Lauster, Roland, Marx, Uwe, Materne, Eva-Maria, Sakharov, Dmitry A., Sonntag, Frank, Süßbier, Ute, Tonevitsky, Alexander G., Trushkin, Evgeny V., Wagner, Ilka   +11 more
core   +2 more sources