Results 191 to 200 of about 122,515 (310)

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

iMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou, Zishuai Wang, Chenghao Hu, Shuhan Deng, Changyun Cai, Yanfang Wang, Shang‐Tong Li, Lijing Bai, Kui Li   +8 more
wiley   +1 more source

Synergistic Enhancement of Peripheral Nerve Regeneration via Ibudilast-Primed Three-Dimensional Spheroid Culture of Human Adipose-Derived Stem Cells. [PDF]

Pharmaceuticals (Basel)
Bang JY, Lim NK.
europepmc   +1 more source

Slipper Limpet (Crepidula fornicata) Shells Support In Vitro Osteogenesis of Human Adipose-Derived Stem Cells. [PDF]

Mar Drugs, 2023
De Mori A, Alasa UJ, Mühlhölzl A, Blunn G.   +3 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

IGF2BP3-dependent glutamine/BCAA metabolic rewiring rejuvenates aged human adipose-derived stem cells for enhanced tissue regeneration. [PDF]

Cell Discov
Li Z, Feng L, Wei X, Li H, Zhu Y, Wang H, Liu J, Luo L, Zheng Z, Song B, Shen L, Hu D.   +11 more
europepmc   +1 more source

Human adipose-derived stem cells preconditioned with a novel herbal formulation Jing Shi attenuate doxorubicin-induced cardiac damage. [PDF]

Aging (Albany NY), 2023
Hsieh DJ, Tsai BC, Barik P, Shibu MA, Kuo CH, Kuo WW, Lin PY, Shih CY, Lin SZ, Ho TJ, Huang CY.   +10 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Therapeutic Effects of Noninvasive Electrical Stimulation in Combination Transplantation of Human Adipose-Derived Stem Cells-Derived Dopaminergic Neuron on the Monkey Model of Parkinson's Disease. [PDF]

MedComm (2020)
Huang C, Gao S, Zheng X, Song X, Wu J, Liao K, Li J, Lin Y, Li C, Lu Y, Feng J, Wei H, Wang L, Xu H, Wang W, Chen Y, Wu J, Gao J, Song J, Shi C, Zhang J, Yan S.   +21 more
europepmc   +1 more source

Human Adipose-Derived Stem Cells Reduce Cellular Damage after Experimental Spinal Cord Injury in Rats. [PDF]

Biomedicines, 2023
Vialle EN, Fracaro L, Barchiki F, Dominguez AC, Arruda AO, Olandoski M, Brofman PRS, Kuniyoshi Rebelatto CL.   +7 more
europepmc   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source