The Human Omental Adipose Depot Mitigates Inflammation, Immune Response, and Oxidative Stress Pathways in Response to Injury via Its Secretome [PDF]
BiologyHuman intraperitoneal omental adipose tissue, part of the visceral adipose depots, surrounds the abdominal organs and has functions distinct from the subcutaneous adipose depots.
Meredith Krause-Hauch +5 more
doaj +2 more sources
Downregulation of the protein synthesis machinery is a major regulatory event during early adipogenic differentiation of human adipose-derived stromal cells [PDF]
Stem Cell Research, 2017 Commitment of adult stem cells involves the activation of specific gene networks regulated from transcription to protein synthesis. Here, we used ribosome profiling to identify mRNAs regulated at the translational level, through both differential ...
Bruna H. Marcon +9 more
doaj +2 more sources
TWIST1 Silencing Enhances In Vitro and In Vivo Osteogenic Differentiation of Human Adipose-Derived Stem Cells by Triggering Activation of BMP-ERK/FGF Signaling and TAZ Upregulation [PDF]
Stem Cells, 2015 Abstract Mesenchymal stem cells (MSCs) show promise for cellular therapy and regenerative medicine. Human adipose tissue-derived stem cells (hASCs) represent an attractive source of seed cells in bone regeneration. How to effectively improve osteogenic differentiation of hASCs in the bone tissue engineering has become a very important ...
QUARTO, NATALINA +3 more
openaire +4 more sources
A xenogeneic-free protocol for isolation and expansion of human adipose stem cells for clinical uses. [PDF]
PLoS ONE, 2013 Human adipose stem cells (HASCS) play a crucial role in the fields of regenerative medicine and tissue engineering for different reasons: the abundance of adipose tissue, their easy harvesting, the ability to multipotent differentiation and the fact that
Carmen Escobedo-Lucea +10 more
doaj +2 more sources
Rapid Generation of Fusable Cell Beads for Multi-Scale Human Living Materials Assembly. [PDF]
Small MethodsLiving beads are produced through the combination of metabolic glycoengineering, click chemistry, and superhydrophobic surfaces, to develop a spheroid alternative for bottom‐up tissue engineering and disease modeling. The living beads present a size independent of cell density and a rapid fabrication methodology, providing a platform that can fuse into
Moura BS +5 more
europepmc +2 more sources
Adipose-Derived Stem Cells as Therapeutic Approach in Hypertrophic Scar Formation-A Systematic Review. [PDF]
Int Wound JABSTRACT Despite numerous therapeutic approaches, the inhibition of hypertrophic scar formation remains a major challenge. Adipose‐derived stem cells (ADSCs) have been shown to improve wound healing, including remodelling, in vivo. A systematic review was conducted using the electronic databases PubMed, Web of Science, Embase and Medline.
Kohlhauser M +5 more
europepmc +2 more sources
Cinnamaldehyde and eugenol change the expression folds of AKT1 and DKC1 genes and decrease the telomere length of human adipose-derived stem cells (hASCs): An experimental and in silico study [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): To investigate the effect of cinnamaldehyde and eugenol on the telomere-dependent senescence of stem cells. In addition, to search the probable targets of mentioned phytochemicals between human telomere interacting proteins (TIPs) using in ...
Abdorrahim Absalan +3 more
doaj +3 more sources
Cells, 2019 Background: Recently, human adipose-derived stem cells (hASCs) were discovered in the human subcutaneous adipose tissue. PLTMax Human Platelet Lysate (PLTMax), a supplement refined from human platelets, has been reported to have proliferative effects on ...
Natsuko Kakudo +3 more
doaj +2 more sources
Cell Transplantation, 2017 Adipose-derived stem cells (ASCs) can be applied extensively in the clinic because they can be easily isolated and cause less donor-site morbidity; however, their application can be complicated by patient-specific factors, such as age and harvest site ...
Meichen Liu +9 more
doaj +2 more sources
The preventive and therapeutic effects of intravenous human adipose-derived stem cells in Alzheimer's disease mice. [PDF]
PLoS ONE, 2012 Alzheimer's disease (AD) is characterized by the accumulation of amyloid plaques and neurofibrillary tangles accompanied by cognitive dysfunction. The aim of the present study was to elucidate preventive and therapeutic potential of stem cells for AD ...
Saeromi Kim +6 more
doaj +2 more sources