Results 41 to 50 of about 2,499 (150)

Transcriptional signature of human adipose tissue-derived stem cells (hASCs) preconditioned for chondrogenesis in hypoxic conditions

Experimental Cell Research, 2009
Hypoxia is an important factor involved in the control of stem cells. To obtain a better insight into the phenotypical changes brought about by hypoxic preconditioning prior to chondrogenic differentiation; we have investigated growth, colony-forming and chondrogenic capacity, and global transcriptional responses of six adipose tissue-derived stem cell
Pilgaard, Linda, Lund, Pia, Duroux, Meg; id_orcid 0000-0001-9457-2429, Lockstone, H., Taylor, J., Emmersen, Jeppe; id_orcid 0000-0001-6244-1280, Fink, Trine; id_orcid 0000-0001-7578-1137, Ragoussis, J., Zachar, Vladimir; id_orcid 0000-0002-5279-2690   +8 more
openaire   +3 more sources

Polycystin-2 mediates mechanical tension-induced osteogenic differentiation of human adipose-derived stem cells by activating transcriptional co-activator with PDZ-binding motif

Frontiers in Physiology, 2022
Human adipose-derived stem cells (hASCs) have multi-directional differentiation potential including osteogenic differentiation. Mechanical stimulation is thought to be a key regulator of bone remodeling and has been proved to promote osteogenic ...
Liang Wang, Liang Wang, Yahui Lu, Guanhui Cai, Hongyu Chen, Gen Li, Luwei Liu, Lian Sun, Zhaolan Guan, Wen Sun, Chunyang Zhao, Hua Wang   +11 more
doaj   +1 more source

Effects of stem cells from inducible brown adipose tissue on diet-induced obesity in mice

Scientific Reports, 2021
Adipose-derived mesenchymal stem cells (ASCs) are a promising option for the treatment of obesity and its metabolic co-morbidities. Despite the recent identification of brown adipose tissue (BAT) as a potential target in the management of obesity, the ...
Enrique Calvo, Noelia Keiran, Catalina Núñez-Roa, Elsa Maymó-Masip, Miriam Ejarque, Joan Sabadell-Basallote, María del Mar Rodríguez-Peña, Victòria Ceperuelo-Mallafré, Jesús Seco, Ester Benaiges, Theodora Michalopoulou, Rosa Jorba, Joan Vendrell, Sonia Fernández-Veledo   +13 more
doaj   +1 more source

The preventive and therapeutic effects of intravenous human adipose-derived stem cells in Alzheimer's disease mice. [PDF]

PLoS ONE, 2012
Alzheimer's disease (AD) is characterized by the accumulation of amyloid plaques and neurofibrillary tangles accompanied by cognitive dysfunction. The aim of the present study was to elucidate preventive and therapeutic potential of stem cells for AD ...
Saeromi Kim, Keun-A Chang, Jeong a Kim, Hyeong-Geun Park, Jeong Chan Ra, Hye-Sun Kim, Yoo-Hun Suh   +6 more
doaj   +1 more source

Radioelectric Asymmetric Conveyed Fields and Human Adipose-Derived Stem Cells Obtained with a Nonenzymatic Method and Device: A Novel Approach to Multipotency

Cell Transplantation, 2014
Human adipose-derived stem cells (hASCs) have been recently proposed as a suitable tool for regenerative therapies for their simple isolation procedure and high proliferative capability in culture.
Margherita Maioli, Salvatore Rinaldi, Sara Santaniello, Alessandro Castagna, Gianfranco Pigliaru, Alessandro Delitala, Francesca Bianchi, Carlo Tremolada, Vania Fontani, Carlo Ventura   +9 more
doaj   +1 more source

Isolation, Characterization, and Differentiation Potential of Canine Adipose-Derived Stem Cells

Cell Transplantation, 2010
Adipose tissue may represent a potential source of adult stem cells for tissue engineering applications in veterinary medicine. It can be obtained in large quantities, under local anesthesia, and with minimal discomfort.
N. M. Vieira, V. Brandalise, E. Zucconi, M. Secco, B. E. Strauss, M. Zatz Ph.D.   +5 more
doaj   +1 more source

Nanocrystalline Hydroxyapatite Loaded with Resveratrol in Colloidal Suspension Improves Viability, Metabolic Activity and Mitochondrial Potential in Human Adipose-Derived Mesenchymal Stromal Stem Cells (hASCs) [PDF]

Polymers, 2019
In response to the demand for new multifunctional materials characterized by high biocompatibility, hydrogel (HG) nanocomposites as a platform for bioactive compound delivery have been developed and fabricated. A specific crosslinking/copolymerization chemistry was used to construct hydrogels with a controlled network organization.
Krzysztof Marycz, Agnieszka Smieszek, Justyna Trynda, Paulina Sobierajska, Sara Targonska, Lukasz Grosman, Rafal J. Wiglusz   +6 more
openaire   +2 more sources

Periostin accelerates bone healing mediated by human mesenchymal stem cell-embedded hydroxyapatite/tricalcium phosphate scaffold. [PDF]

PLoS ONE, 2015
Periostin, an extracellular matrix protein, is expressed in bone, more specifically, the periosteum and periodontal ligaments, and plays a key role in formation and metabolism of bone tissues.
Soon Chul Heo, Won Chul Shin, Mi Jeong Lee, Ba Reun Kim, Il Ho Jang, Eun-Jung Choi, Jung Sub Lee, Jae Ho Kim   +7 more
doaj   +1 more source

Current Status of Human Adipose–Derived Stem Cells: Differentiation into Hepatocyte-Like Cells

The Scientific World Journal, 2011
The shortage of human organ donors and the low cell quality of available liver tissues represent major obstacles for the clinical application of orthotropic liver transplantation and hepatocyte transplantation, respectively. Therefore, worldwide research
Feras Al Battah, Joery De Kock, Tamara Vanhaecke, Vera Rogiers   +3 more
doaj   +1 more source

The Effect of Human Adipose Stem Cell-Conditioned Medium (hASC-CM) in Photoaged Skin

Journal of Stem Cells and Regenerative Medicine
Background: Ultraviolet (UV) exposure causes direct and indirect damages to skin structures. Human adipose stem cell-conditioned medium (hASC-CM) is a collection of several soluble factors, such as cytokines, chemokines, and Growth Factors (GF), secreted by almost all living cells in the extracellular space which support wound healing and skin ...
Winawati Eka, Putri, Meidyta Sinantryana, Widyaswari, Cita Rosita Sigit, Prakoeswa, David Sajid, Muhammad, Deny Febriwijaya, Romadhani, Nadia, Nisaussholihah   +5 more
openaire   +2 more sources