Results 61 to 70 of about 4,526 (199)
PLoS ONE, 2014 Fibroblast growth factor 21 (FGF21) has evolved as a major metabolic regulator, the pharmacological administration of which causes weight loss, insulin sensitivity and glucose control in rodents and humans. To understand the molecular mechanisms by which FGF21 exerts its metabolic effects, we developed a human in vitro model of adipocytes to examine ...
Darwin V Lee +7 more
openaire +4 more sources
npj Regenerative Medicine, 2023 Our previous work demonstrated the tendon-derived extracellular matrix (ECM) extracts as vital niches to specifically direct mesenchymal stem cells towards tenogenic differentiation.
Tian Tu +9 more
doaj +1 more source
Comparison of the direct effects of human adipose- and bone-marrow-derived stem cells on postischemic cardiomyoblasts in an in vitro simulated ischemia-reperfusion model. [PDF]
, 2013 Regenerative therapies hold a promising and exciting future for the cure of yet untreatable diseases, and mesenchymal stem cells are in the forefront of this approach.
Benkő, Zsolt +6 more
core +2 more sources
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Advanced Healthcare Materials, EarlyView.Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
Cell Transplantation, 2012 Hypoxia plays an important role in limiting the engraftment, survival, and function of intrahepatically transplanted islets. Mesenchymal stem cells (MSCs) were recently used in animal models of islet transplantation not only to reduce allograft rejection
Giuseppe Cavallari +9 more
doaj +1 more source
Development of micro-patterned surfaces of poly(butylene succinate) by micromolding for guided tissue engineering [PDF]
, 2012 Native tissues present complex architectures at the micro- and nanoscale that dictate their biological function. Several microfabrication techniques have been employed for engineering polymeric surfaces that could replicate in vitro these micro- and ...
Coutinho, Daniela F. +3 more
core +1 more source
Advanced Materials, EarlyView.Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa +6 more
wiley +1 more source
The Influence of Aging on the Regenerative Potential of Human Adipose Derived Mesenchymal Stem Cells
Stem Cells International, 2016 Tissue regeneration using human adipose derived mesenchymal stem cells (hASCs) has significant potential as a novel treatment for many degenerative bone and joint diseases.
Monika Marędziak +4 more
doaj +1 more source
Differentiation of adipose-derived stem cells to chondrocytes using electrospraying
Scientific Reports, 2021 An important challenge in the fabrication of tissue engineered constructs for regenerative medical applications is the development of processes capable of delivering cells and biomaterials to specific locations in a consistent manner.
Nasim Nosoudi +7 more
doaj +1 more source
Hydrogel-based microfluidics for vascular tissue engineering [PDF]
, 2016 In this work, we have explored 3-D co-culture of vasculogenic cells within a synthetically modified fibrin hydrogel. Fibrinogen was covalently linked with PEG-NHS in order to improve its degradability resistance and physico-optical properties.
Bagratashvili, Victor N. +10 more
core +2 more sources