Results 51 to 60 of about 2,499 (150)

Fibroblast growth factor-2 stimulates proliferation of human adipose-derived stem cells via Src activation

Stem Cell Research & Therapy, 2019
Background Human adipose-derived stem cells (hASCs) are a subset of mesenchymal stem cells (MSCs); it has been regarded as one of the most promising stem cells.
Yuanyuan Ma, Natsuko Kakudo, Naoki Morimoto, Fangyuan Lai, Shigeru Taketani, Kenji Kusumoto   +5 more
doaj   +1 more source

Subcutaneous Construction of Engineered Adipose Tissue with Fat Lobule-Like Structure Using Injectable Poly-Benzyl-L-Glutamate Microspheres Loaded with Adipose-Derived Stem Cells. [PDF]

PLoS ONE, 2015
Porous microcarriers were fabricated from synthesized poly(γ-benzyl-L-glutamate) (PBLG) polymer to engineer adipose tissue with lobule-like structure via the injectable approach.
Wentao Sun, Jianjun Fang, Qi Yong, Sufang Li, Qingping Xie, Jingbo Yin, Lei Cui   +6 more
doaj   +1 more source

Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration

npj Regenerative Medicine, 2023
Our previous work demonstrated the tendon-derived extracellular matrix (ECM) extracts as vital niches to specifically direct mesenchymal stem cells towards tenogenic differentiation.
Tian Tu, Yuan Shi, Boya Zhou, Xiaoyu Wang, Wenjie Zhang, Guangdong Zhou, Xiumei Mo, Wenbo Wang, Jinglei Wu, Wei Liu   +9 more
doaj   +1 more source

Vocal Outcomes After Cell‐Based Outer Vocal Fold Implant in Porcine Bilateral Vocal Fold Resection

The Laryngoscope, EarlyView.
Cell‐based outer vocal fold replacement (COVR) was evaluated in a porcine model of bilateral vocal fold injury using longitudinal acoustic analysis and histologic assessment. COVR implantation resulted in recovery of the nonperiodic acoustic parameter Q50 to preoperative levels by 6 months, with implanted human adipose‐derived stem cells detected in 7 ...
Keer Zhang, Georgia Crane, Mateo Ruiz Alvarez, Alexandra Klomhaus, Yazeed Alhiyari, Bhavani Gowda, Michael Döllinger, Jennifer Long   +7 more
wiley   +1 more source

Mesenchymal Stem Cells and Islet Cotransplantation in Diabetic Rats: Improved Islet Graft Revascularization and Function by Human Adipose Tissue-Derived Stem Cells Preconditioned with Natural Molecules

Cell Transplantation, 2012
Hypoxia plays an important role in limiting the engraftment, survival, and function of intrahepatically transplanted islets. Mesenchymal stem cells (MSCs) were recently used in animal models of islet transplantation not only to reduce allograft rejection
Giuseppe Cavallari, Elena Olivi, Francesca Bianchi, Flavia Neri, Laura Foroni, Sabrina Valente, Gaetano La Manna, Bruno Nardo, Sergio Stefoni, Carlo Ventura   +9 more
doaj   +1 more source

Current Trends and Future Prospects of Integrating Electrospinning With 3D Printing Techniques for Mimicking Bone Extracellular Matrix Scaffolds

Journal of Polymer Science, Volume 63, Issue 6, Page 1481-1504, 15 March 2025.
ABSTRACT This article presents a review of the recent findings on the combination of electrospun nanofibers and three‐dimensional (3D)‐printed structures for extracellular matrix (ECM) scaffolds for bone tissue engineering. We explore the synergy between electrospinning (ES), which produces highly porous, fibrous structures from materials like collagen
Kardo Khalid Abdullah, Kolos Molnár
wiley   +1 more source

The Influence of Aging on the Regenerative Potential of Human Adipose Derived Mesenchymal Stem Cells

Stem Cells International, 2016
Tissue regeneration using human adipose derived mesenchymal stem cells (hASCs) has significant potential as a novel treatment for many degenerative bone and joint diseases.
Monika Marędziak, Krzysztof Marycz, Krzysztof A. Tomaszewski, Katarzyna Kornicka, Brandon Michael Henry   +4 more
doaj   +1 more source

Differentiation of adipose-derived stem cells to chondrocytes using electrospraying

Scientific Reports, 2021
An important challenge in the fabrication of tissue engineered constructs for regenerative medical applications is the development of processes capable of delivering cells and biomaterials to specific locations in a consistent manner.
Nasim Nosoudi, Christoph Hart, Ian McKnight, Mehdi Esmaeilpour, Taher Ghomian, Amir Zadeh, Regan Raines, Jaime E. Ramirez Vick   +7 more
doaj   +1 more source

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, Volume 38, Issue 44, 7 August 2026.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source

Fibroblast Growth Factor 21 Improves Insulin Sensitivity and Synergizes with Insulin in Human Adipose Stem Cell-Derived (hASC) Adipocytes

PLoS ONE, 2014
Fibroblast growth factor 21 (FGF21) has evolved as a major metabolic regulator, the pharmacological administration of which causes weight loss, insulin sensitivity and glucose control in rodents and humans. To understand the molecular mechanisms by which FGF21 exerts its metabolic effects, we developed a human in vitro model of adipocytes to examine ...
Darwin V Lee, Dongmei Li, Qingyun Yan, Yimin Zhu, Bryan Goodwin, Roberto Calle, Martin B Brenner, Saswata Talukdar   +7 more
openaire   +4 more sources