Results 31 to 40 of about 2,499 (150)

Global Single-Cell Sequencing Landscape of Adipose Tissue of Different Anatomical Site Origin in Humans

Stem Cells International, 2023
Chronic refractory wounds (CRW) are one of the most serious clinical challenges for surgeons to address. Stromal vascular fraction gels (SVFG), including human adipose stem cells (hASCs), have excellent vascular regenerative and tissue repair properties.
Shixing Gu, Zhenyu Gong, Shuncai Liu, Guohao Lu, Yu Ling, Yanlin Wei, Ting Li, Ronghe Gu, Yongxian Rong, Junjun Li, Hongmian Li   +10 more
doaj   +1 more source

A xenogeneic-free protocol for isolation and expansion of human adipose stem cells for clinical uses. [PDF]

PLoS ONE, 2013
Human adipose stem cells (HASCS) play a crucial role in the fields of regenerative medicine and tissue engineering for different reasons: the abundance of adipose tissue, their easy harvesting, the ability to multipotent differentiation and the fact that
Carmen Escobedo-Lucea, Carmen Bellver, Carolina Gandia, Andres Sanz-Garcia, Francisco J Esteban, Vicente Mirabet, Giancarlo Forte, Isabel Moreno, Melissa Lezameta, Angel Ayuso-Sacido, José M Garcia-Verdugo   +10 more
doaj   +1 more source

Selective Proliferation of Highly Functional Adipose-Derived Stem Cells in Microgravity Culture with Stirred Microspheres

Cells, 2021
Therapeutic effects of adult stem-cell transplantations are limited by poor cell-retention in target organs, and a reduced potential for optimal cell differentiation compared to embryonic stem cells.
Takanobu Mashiko, Koji Kanayama, Natsumi Saito, Takako Shirado, Rintaro Asahi, Masanori Mori, Kotaro Yoshimura   +6 more
doaj   +1 more source

Neuronal induction and bioenergetics characterization of human forearm adipose stem cells from Parkinson's disease patients and healthy controls.

PLoS ONE, 2022
Neurodegenerative diseases, such as Parkinson's disease, are heterogeneous disorders with a multifactorial nature involving impaired bioenergetics. Stem-regenerative medicine and bioenergetics have been proposed as promising therapeutic targets in the ...
Ingrid González-Casacuberta, Dolores Vilas, Claustre Pont-Sunyer, Ester Tobías, Judith Cantó-Santos, Laura Valls-Roca, Francesc Josep García-García, Glòria Garrabou, Josep Maria Grau-Junyent, Maria Josep Martí, Francesc Cardellach, Constanza Morén   +11 more
doaj   +2 more sources

Induction of the CD24 Surface Antigen in Primary Undifferentiated Human Adipose Progenitor Cells by the Hedgehog Signaling Pathway

Biologics, 2021
In the murine model system of adipogenesis, the CD24 cell surface protein represents a valuable marker to label undifferentiated adipose progenitor cells.
Francesco Muoio, Stefano Panella, Yves Harder, Tiziano Tallone   +3 more
doaj   +1 more source

Priming with caffeic acid enhances the potential and survival ability of human adipose-derived stem cells to counteract hypoxia

Regenerative Therapy, 2023
The therapeutic effectiveness of stem cells after transplantation is hampered by the hypoxic milieu of chronic wounds. Prior research has established antioxidant priming as a thorough plan to improve stem cell performance.
H.M. Shifa ul Haq, Ramla Ashfaq, Azra Mehmood, Warda Shahid, Hafiz Ghufran Azam, Maryam Azam, Saba Tasneem, Shehla Javed Akram, Kausar Malik, Sheikh Riazuddin   +9 more
doaj   +1 more source

Chemically Defined Xeno- and Serum-Free Cell Culture Medium to Grow Human Adipose Stem Cells

Cells, 2021
Adipose tissue is an abundant source of stem cells. However, liposuction cannot yield cell quantities sufficient for direct applications in regenerative medicine.
Stefano Panella, Francesco Muoio, Valentin Jossen, Yves Harder, Regine Eibl-Schindler, Tiziano Tallone   +5 more
doaj   +1 more source

Anti-obesity effect and mechanism of mesenchymal stem cells influence on obese mice

Open Life Sciences, 2021
Mesenchymal stem cells (MSCs) can be obtained from almost all tissues and present promising therapeutic effects for metabolic diseases. Human adipose-derived MSCs (hASCs) have recently been widely studied due to their easy access and low immunity.
Xie Zongyan, Cheng Yu, Zhang Qi, Hao Haojie, Yin Yaqi, Zang Li, Wang Xuhong, Mu Yiming   +7 more
doaj   +1 more source

Downregulation of the protein synthesis machinery is a major regulatory event during early adipogenic differentiation of human adipose-derived stromal cells

Stem Cell Research, 2017
Commitment of adult stem cells involves the activation of specific gene networks regulated from transcription to protein synthesis. Here, we used ribosome profiling to identify mRNAs regulated at the translational level, through both differential ...
Bruna H. Marcon, Fabíola B. Holetz, Guillermo Eastman, Ana Carolina Origa-Alves, Mariana Andrea Amorós, Alessandra Melo de Aguiar, Carmen K. Rebelatto, Paulo R.S. Brofman, Jose Sotelo-Silveira, Bruno Dallagiovanna   +9 more
doaj   +1 more source

Human Adipose-Derived Stromal/Stem Cells Protect Against STZ-Induced Hyperglycemia: Analysis of hASC-Derived Paracrine Effectors [PDF]

Stem Cells, 2014
Abstract Adipose-derived stromal/stem cells (ASCs) ameliorate hyperglycemia in rodent models of islet transplantation and autoimmune diabetes, yet the precise human ASC (hASC)-derived factors responsible for these effects remain largely unexplored.
Kono, Tatsuyoshi M., Sims, Emily K., Moss, Dan R., Yamamoto, Wataru, Ahn, Geonyoung, Diamond, Julie, Tong, Xin, Day, Kathleen H., Territo, Paul R., Hanenberg, Helmut, Traktuev, Dmitry O., March, Keith L., Evans-Molina, Carmella   +12 more
openaire   +2 more sources