Results 101 to 110 of about 13,726 (210)

Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against trypanosoma brucei [PDF]

, 2012
A non-targeted metabolomics-based approach is presented that enables the study of pathways in response to drug action with the aim of defining the mode of action of trypanocides.
Burgess, K., Burchmore, Richard J S, Barrett, M.P., Creek, D.J., Vincent, I.M., Woods, Debra, Karl Burgess, Richard J S Burchmore, Woods, Debra J, Creek, Darren, Debra J. Woods (167740), Creek, Darren John, Isabel M Vincent, Vincent, Isabel M, Michael P Barrett, Darren J. Creek (167726), Woods, D.J., Isabel M. Vincent (167717), Woods Debra J., Burgess Karl, Burgess, Karl, Burchmore, Richard, Barrett, Michael P, Vincent, Isabel, Barrett Michael P., Burchmore, R.J.S., Creek Darren J., Richard J. S. Burchmore (167742), Vincent Isabel M., Darren J Creek, Karl Burgess (167732), Debra J Woods, Barrett, Michael, Michael P. Barrett (167748), Burchmore Richard J. S.   +34 more
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The importance of veterinary policy in preventing zoonoses emergence and re-emergence: Examining the case of Human African Trypanosomiasis in Uganda

Frontiers in Public Health, 2014
Rapid changes in human behaviour, resource utilisation and other extrinsic environmental factors continue to threaten the current distribution of several endemic and neglected zoonoses worldwide.
Anna L Okello, Susan C Welburn
doaj   +1 more source

Using detergent to enhance detection sensitivity of African trypanosomes in human CSF and blood by Loop-Mediated Isothermal Amplification (LAMP) [PDF]

, 2011
<p><b>Background:</b> The loop-mediated isothermal amplification (LAMP) assay, with its advantages of simplicity, rapidity and cost effectiveness, has evolved as one of the most sensitive and specific methods for the detection of a ...
Gibson, W., Thekisoe, Oriel M M, Dumler, JS, Olga V. Nikolskaia, Olga V Nikolskaia, Liam J Morrison, Inoue, N., Noboru Inoue, Liam J. Morrison, Dennis J Grab, Oriel M. M. Thekisoe, Dumler J. Stephen, Grab, DJ, J. Stephen Dumler, Dumler, J.S., J Stephen Dumler, Morrison, L.J., Nikolskaia Olga V., Dumler, J Stephen, Nikolskaia, O.V., Nikolskaia, OV, Grab, D.J., Grab, Dennis J, Wendy Gibson, Morrison Liam J., Grab Dennis J., Inoue, N, Gibson, WC, Thekisoe, Oriel M. M., Oriel M M Thekisoe, Inoue, Noboru, Thekisoe Oriel M. M., Morrison, Liam J; id_orcid, Gibson Wendy, Thekisoe, OMM, Morrison, L, Inoue Noboru, Dennis J. Grab, Nikolskaia, Olga V, Gibson, Wendy   +39 more
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The burden and spatial distribution of bovine African trypanosomes in small holder crop-livestock production systems in Tororo District, south-eastern Uganda

Parasites & Vectors, 2014
Background African animal trypanosomiasis (AAT) is considered to be one of the greatest constraints to livestock production and livestock-crop integration in most African countries.
Dennis Muhanguzi, Kim Picozzi, Jan Hattendorf, Michael Thrusfield, John David Kabasa, Charles Waiswa, Susan Christina Welburn   +6 more
doaj   +1 more source

Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis

Frontiers in Immunology, 2019
Trypanosomiasis has been recognized as a scourge in sub-Saharan Africa for centuries. The disease, caused by protozoan parasites of the Trypanosoma genus, is a major cause of mortality and morbidity in animals and man. Human African trypanosomiasis (HAT),
Peter G. E. Kennedy, Jean Rodgers
doaj   +1 more source

Estimates of the duration of the early and late stage of gambiense sleeping sickness

, 2008
Background: The durations of untreated stage 1 (early stage, haemo-lymphatic) and stage 2 (late stage, meningo-encephalitic) human African trypanosomiasis (sleeping sickness) due to Trypanosoma brucei gambiense are poorly quantified, but key to ...
Filipe, João AN, Haydon Daniel T, Filipe João AN, Chappuis, F., Checchi Francesco, Haydon, D.T., Checchi, F, Checchi, Francesco, Chandramohan, D, Chappuis, F, Chandramohan, Daniel, Filipe, J A N, Filipe, João A N., Haydon, Daniel T, Haydon, D T, Filipe, J.A., Haydon, Daniel T., Checchi, F., Chandramohan, D., Chappuis, François, Chappuis François, Chandramohan Daniel   +21 more
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Options for field diagnosis of human african trypanosomiasis.

, 2005
Human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense or T. b. rhodesiense remains highly prevalent in several rural areas of sub-Saharan Africa and is lethal if left untreated.
Chappuis, F, Loutan, L, Chappuis, F., Lejon, V., Simarro, P, Büscher, P, Loutan, L., Lejon, V, Simarro, P., Büscher, P.   +9 more
core   +1 more source

Evaluation of the micro-CATT, CATT/Trypanosoma brucei gambiense, and LATEX/T. b. gambiense methods for serodiagnosis and surveillance of human African trypanosomiasis in West and Central Africa

Bulletin of the World Health Organization, 2002
OBJECTIVE: To evaluate the performance of serological tests using dried blood on filter-papers (micro-card agglutination test for trypanosomiasis (micro-CATT)) performed under field and laboratory conditions and using whole blood ((CATT/T.b.
Truc Philippe, Lejon Veerle, Magnus Eddy, Jamonneau Vincent, Nangouma Auguste, Verloo Didier, Penchenier Laurent, Büscher Philippe   +7 more
doaj  

Human African Trypanosomiasis: Epidemiology and Control

, 2006
Human African trypanosomiasis (HAT), or sleeping sickness, describes not one but two discrete diseases: that caused by Trypanosoma brucei rhodesiense and that caused by T. b. gambiense. The Gambian form is currently a major public health problem over vast areas of central and western Africa, while the zoonotic, Rhodesian form continues to present a ...
Fèvre, Eric M., Picozzi, K., Jannin, J., Welburn, S.C., Maudlin, I.   +4 more
openaire   +3 more sources

The use of Multiple Displacement Amplification to increase the detection and genotyping of Trypanosoma samples immobilised on FTA filters. [PDF]

, 2007
Whole genome amplification methods are a recently developed tool for amplifying DNA from limited template. We report its application in trypanosome infections, characterized by low parasitemias.
Sweeney, L., Turner, C.M.R., Morrison, L.J., Likeufack, A.C.L., Truc, P., Tait, A., McCormack, G., MacLeod, A.   +7 more
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