Results 111 to 120 of about 13,726 (210)

Africa and the Cattle Without History

Global Environment
African historiography of tsetse-borne trypanosomiasis has yet to fully embrace the genetic basis of cattle tolerance to the disease due to the literature’s emphasis on human illness and landscape modification.
Tad Brown
doaj   +1 more source

Development of multiplex serological assay for the detection of human African trypanosomiasis

, 2016
Human African trypanosomiasis (HAT) is a disease caused by Kinetoplastid infection. Serological tests are useful for epidemiological surveillance. The aim of this study was to develop a multiplex serological assay for HAT to assess the diagnostic value ...
Mwau, Matilu, Salam, Md. Abdus, Miura, Masashi, Hirayama, Kenji, Hamano, Shinjiro, Kaneko, Satoshi, Mwangi, Anne Wanjiru, Itoh, Makoto, Nzou, Samson Muuo, Fujii, Yoshito   +9 more
core   +1 more source

A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction

Microbiology Spectrum
Trypanosoma brucei is a protozoan parasite that causes human and animal African trypanosomiases (HAT and AAT). Cardiac symptoms are commonly reported in HAT patients, and intracardiac parasites with accompanying myocarditis have been observed in both ...
Nathan P. Crilly, Marcelle Dina Zita, Alexander K. Beaver, Polina Sysa-Shah, Aashik Bhalodia, Kathy Gabrielson, Luigi Adamo, Monica R. Mugnier   +7 more
doaj   +1 more source

A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against Trypanosoma brucei in vitro

, 2013
Recently, the World Health Organization approved the nifurtimox–eflornithine combination therapy for the treatment of human African trypanosomiasis, renewing interest in nitroheterocycle therapies for this and associated diseases.
Smith, Terry K, Westwood, Nicholas J, Rideau, Emeline, Stewart, Gavin, Zhou, Linna, Westwood, Nicholas James   +5 more
core   +1 more source

Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study (IMPAMEL II).

, 2005
BACKGROUND: Treatment of late-stage human African trypanosomiasis (HAT) with melarsoprol can be improved by shortening the regimen. A previous trial demonstrated the safety and efficacy of a 10-day treatment schedule.
Chappuis, F, Manthelot, C R, Doua, F, Asumu, P, Simarro, P, Josenando, T, Richer, M, Burri, C, Schmid, C, Nangouma, A, Bilenge, C M M   +10 more
core   +1 more source

Coinfection with Schistosoma mansoni Enhances Disease Severity in Human African Trypanosomiasis. [PDF]

J Trop Med, 2023
Mitalo NS, Waiganjo NN, Mokua Mose J, Bosire DO, Oula JO, Orina Isaac A, Nyabuga Nyariki J.   +6 more
europepmc   +1 more source

Human African Trypanosomiasis (Sleeping Sickness)-Epidemiology, Clinical Manifestations, Diagnosis, Treatment, and Prevention. [PDF]

Curr Trop Med Rep, 2023
Ortiz-Martínez Y, Kouamé MG, Bongomin F, Lakoh S, Henao-Martínez AF.   +4 more
europepmc   +1 more source

Towards the sustainable elimination of gambiense human African trypanosomiasis in Côte d'Ivoire using an integrated approach. [PDF]

PLoS Negl Trop Dis, 2023
Kaba D, Koffi M, Kouakou L, N'Gouan EK, Djohan V, Courtin F, N'Djetchi MK, Coulibaly B, Adingra GP, Berté D, Ta BTD, Koné M, Traoré BM, Sutherland SA, Crump RE, Huang CI, Madan J, Bessell PR, Barreaux A, Solano P, Crowley EH, Rock KS, Jamonneau V.   +22 more
europepmc   +1 more source

Human African trypanosomiasis cases diagnosed in non-endemic countries (2011-2020). [PDF]

PLoS Negl Trop Dis, 2022
Franco JR, Cecchi G, Priotto G, Paone M, Kadima Ebeja A, Simarro PP, Diarra A, Sankara D, Zhao W, Dagne DA.   +9 more
europepmc   +1 more source

Gambiense human African trypanosomiasis: the bumpy road to elimination. [PDF]

Curr Opin Infect Dis, 2022
Hasker E, Hope A, Bottieau E.
europepmc   +1 more source