Results 41 to 50 of about 10,333 (209)

Molecular identification of trypanosomes in cattle in Malawi using PCR methods and nanopore sequencing: epidemiological implications for the control of human and animal trypanosomiases

Parasite, 2020
This study aimed to identify trypanosomes infecting cattle in Malawi in order to understand the importance of cattle in the transmission dynamics of Human African Trypanosomiasis (HAT) and Animal African Trypanosomosis (AAT).
Marsela Megasari, Hayashida Kyoko, Nakao Ryo, Chatanga Elisha, Gaithuma Alex Kiarie, Naoko Kawai, Musaya Janelisa, Sugimoto Chihiro, Yamagishi Junya   +8 more
doaj   +1 more source

Ultrastructural expansion microscopy reveals unexpected levels of glycosome heterogeneity in African trypanosomes

Journal of Microscopy, EarlyView.
Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson, Rhonda Reigers Powell, Meredith Teilhet Morris   +2 more
wiley   +1 more source

Human African trypanosomiasis

, 2013
Human African trypanosomiasis or sleeping sickness is a neglected tropical disease that affects populations in sub-Saharan Africa. The disease is caused by infection with the gambiense and rhodesiense subspecies of the extracellular parasite Trypanosoma brucei, and is transmitted to humans by bites of infected tsetse flies.
Lejon, Veerle, Bentivoglio, M., Franco, J.R.   +2 more
openaire   +4 more sources

Animal Health Professionals’ Knowledge, Risk Perception and Preventive Practices Towards Zoonotic Infections in Cameroon

Public Health Challenges, Volume 4, Issue 3, September 2025.
ABSTRACT Introduction Animal health professionals act as the first line of defence in zoonosis transmission. By handling animals on a daily basis, they are at risk of contracting zoonotic diseases. However, the lack of data on animal health professional risk perception on zoonotic disease and preventive practices may hamper decision making and policies
Victor Ngu Ngwa, Jarvis Dongmo Bouna, Lorucha Amatama Mouyobo, Frédéric Moffo, Mohamed Moctar Mouliom Mouiche, Herman Okah‐Nnane, Justin Kouamo   +6 more
wiley   +1 more source

Therapy of Human African Trypanosomiasis: Current Situation

Memorias do Instituto Oswaldo Cruz, 1999
This paper is a review of the current situation of the treatment of human African trypanosomiasis. The existing approved drugs are old, toxic and/or expensive. Therapeutic failures are common.
Jorge Atouguia, José Costa
doaj   +1 more source

Exploring the Nexus Between Alcohol Consumption, Sleep Deprivation, and Memory Among Male Students at a Tertiary Institution in Ghana

Brain and Behavior, Volume 15, Issue 8, August 2025.
Among male Ghanaian university students, alcohol consumption and poor sleep quality are highly prevalent and positively correlated. Both factors are associated with cognitive and memory deficits, highlighting the need for targeted health education and interventions.
Daniel L. Egbenya, Lord B. Amponsah, Ireneaus Nyame, El‐Gibbor C. Rolinklaka, Rose Nanabin, Lovinger M. Nyave, Stephen B. G. Oppong, Jephthah K. N. Boadi, Dzifianu A. Edoh‐Torgah, Isaac B. Mensah, Akua A. Karikari   +10 more
wiley   +1 more source

In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone

Drug Development Research, Volume 86, Issue 5, August 2025.
ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Janine Aucamp, Helena D. Janse van Rensburg, Simon S. Mnyakeni‐Moleele, Keisuke Suganuma, David D. N'Da   +4 more
wiley   +1 more source

Challenges facing the elimination of sleeping sickness in west and central Africa: sustainable control of animal trypanosomiasis as an indispensable approach to achieve the goal

Parasites & Vectors, 2015
African trypanosomiases are infectious diseases caused by trypanosomes. African animal trypanosomiasis (AAT) remains an important threat for livestock production in some affected areas whereas human African trypanosomiasis (HAT) is targeted for ...
Gustave Simo, Jean Baptiste Rayaisse
doaj   +1 more source

Synthesis and Chemical Characterization of Chloroquine, Hydroxychloroquine, Zinc, and Cinnamic Acid Organocomplexes: Potential Drug Candidates for SARS‐CoV‐2 Treatment and Microbial Control

ChemistrySelect, Volume 10, Issue 27, July 18, 2025.
Zn‐quinolines were synthesized with high yields of 78% and 85%. The study focuses on drug repositioning to improve properties and reduce toxicity for COVID‐19 treatment. New Zn‐based compounds demonstrated antiviral and antimicrobial activities with low toxicity.
Carla Peron, Paulo Roberto dos Santos, João Pedro de Oliveira Mezzomo, Fernando Joel Scariot, Ariel Maia, Laura Calle Gonzalez, Deise do Nascimento de Freitas, Ana Paula Longaray Delamare, Pablo Machado, Ana Paula Duarte de Souza, Sidnei Moura   +10 more
wiley   +1 more source

More Timely Response to Outbreaks of Zoonotic Compared to Non‐Zoonotic Diseases in Animals in Tanzania

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
A timeliness metrics analysis study was carried out in Tanzania. A total of 98 disease outbreaks were recorded. The time taken to detect, verify and respond to zoonotic diseases was shorter than the time for non‐zoonotic diseases. More investment should be done for the timely management of disease in Tanzania.
Esron Karimuribo, Veronica Masawe, Lars Eik Olav, Doreen Ndossi, Ann‐Katrin Llarena, Calvin Sindato   +5 more
wiley   +1 more source