Results 221 to 230 of about 111,766 (263)

The characteristics of human cranial bone marrow mesenchymal stem cells

Neuroscience Letters, 2015
Recently, cell-based therapy has attracted attention for treatment of central nervous system (CNS) disorders. Bone marrow-derived mesenchymal stem cells (BMSCs) are considered to have good engraftment potential. Therefore, more efficient and less invasive methods to obtain donor cells are required.
Katsuhiro Shinagawa, Takafumi Mitsuhara, Takahito Okazaki, Masaaki Takeda, Satoshi Yamaguchi, Takuro Magaki, Yunosuke Okura, Hiroyuki Uwatoko, Yumi Kawahara, Louis Yuge, Kaoru Kurisu   +10 more
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Electrostimulated bone marrow human mesenchymal stem cells produce follistatin

Cytotherapy, 2009
Follistatin (FST) and the related proteins FSTL1 and FSTL3 are crucial modulators of the transforming growth factor (TGF)-beta superfamily and function by neutralizing activins, a group of proteins implicated in many biologic processes, such as cell proliferation and differentiation, immune responses, various endocrine activities, wound repair ...
Jorge A, Genovese, Cristiano, Spadaccio, Hernan Garcia, Rivello, Yoshiya, Toyoda, Amit N, Patel   +4 more
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Gene delivery to human bone marrow mesenchymal stem cells by microporation

Journal of Biotechnology, 2011
Electroporation has been considered one of the most efficient non-viral based methods to deliver genes regardless of frequently observed high cell mortality. In this study we used a microporation technique to optimise the delivery of plasmid DNA encoding green fluorescence protein (GFP) to human bone marrow mesenchymal stem cells (BM-MSC).
Catarina, Madeira, Sofia C, Ribeiro, Irina S M, Pinheiro, Sofia A M, Martins, Pedro Z, Andrade, Cláudia L, da Silva, Joaquim M S, Cabral   +6 more
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Human Bone Marrow–Derived Mesenchymal Stem Cells in the Treatment of Gliomas

Cancer Research, 2005
AbstractThe poor survival of patients with human malignant gliomas relates partly to the inability to deliver therapeutic agents to the tumor. Because it has been suggested that circulating bone marrow–derived stem cells can be recruited into solid organs in response to tissue stresses, we hypothesized that human bone marrow–derived mesenchymal stem ...
Akira, Nakamizo, Frank, Marini, Toshiyuki, Amano, Asadullah, Khan, Matus, Studeny, Joy, Gumin, Julianne, Chen, Stephen, Hentschel, Giacomo, Vecil, Jennifer, Dembinski, Michael, Andreeff, Frederick F, Lang   +11 more
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Mesenchymal Stem Cells Derived from Human Bone Marrow

2015
Mesenchymal stem cells are found in a number of tissues and have the potential to differentiate into a range of mesenchymal lineages. This ready availability and multipotent character means that mesenchymal stem cells have become a focus for the field of tissue engineering, particularly for the repair of bone and cartilage.
Gardner OF, Alini M, Stoddart MJ
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Culture and Characterization of Human Bone Marrow Mesenchymal Stem Cells

2007
Bone marrow (BM) mesenchymal stem cells (MSCs) are non-hematopoietic cells capable of generating colonies of plastic-adherent marrow mesenchymal cells, each derived from a single cell termed a colony-forming unit fibroblasts (CFU-Fs). In addition to their role in establishing the marrow microenvironment, these cells have been shown to differentiate ...
Bruno, Delorme, Pierre, Charbord
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Human amnion mesenchymal stem cells promote proliferation and osteogenic differentiation in human bone marrow mesenchymal stem cells

Journal of Molecular Histology, 2014
Human amnion mesenchymal stem cells (HAMSCs) can be obtained from human amniotic membrane, a highly abundant and readily available tissue. HAMSC sources present fewer ethical issues, have low immunogenicity, anti-inflammatory properties, considerable advantageous characteristics, and are considered an attractive potential treatment material in the ...
Yuli, Wang, Ying, Yin, Fei, Jiang, Ning, Chen   +3 more
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Clinical Grade Expansion of Human Bone Marrow Mesenchymal Stem Cells

2007
Mesenchymal stem cells or marrow stromal cells (MSCs) represent a multipotent adult cellular population with immunomodulatory functions. In the adult human body, they are present in various niches, but their main source is bone marrow (BM). The regeneration capability of MSCs, their ease to undergo gene modification, as well as their immunosuppressive ...
Sotiropoulou, Panagiota, Perez, Sonia, Papamichail, Michael   +2 more
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A Simple and Reliable Electroporation Method for Human Bone Marrow Mesenchymal Stem Cells

Stem Cells and Development, 2008
Adult human mesenchymal stem cells (hMSCs) are able to differentiate into a range of specific cell types in vitro and in vivo, and thus hold tremendous potential for use in regenerative medicine. Despite this promise, deficient understanding of the mechanisms that regulate their differentiation has precluded their widespread use.
Helledie, T., Nurcombe, V., Cool, S. M.
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Comparison of Human Placenta- and Bone Marrow–Derived Multipotent Mesenchymal Stem Cells

Stem Cells and Development, 2008
Bone marrow is the traditional source of human multipotent mesenchymal stem cells (MSCs), but placenta appears to be an alternative and more readily available source. This study comprehensively compared human placenta–derived MSC (hpMSC) and human bone marrow–derived MSC (hbmMSC) in terms of cell characteristics, optimal growth conditions and in vivo ...
Barlow, Sarah, Brooke, Gary, Chatterjee, Konica, Price, Gareth, Pelekanos, Rebecca, Rossetti, Tony, Doody, Marylou, Venter, Deon, Pain, Scott, Gilshenan, Kristen, Atkinson, Kerry   +10 more
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