Results 271 to 280 of about 180,484 (312)

Generation of Induced Pluripotent Stem Cells from Human Bone Marrow–Derived Mesenchymal Stem Cells

2021
Adult somatic cells can be reprogrammed and become pluripotent called induced pluripotent stem cells (iPSC) when they are induced by the stemness genes. The iPSCs have been representing a research and development platform for cell-based therapies, and even in gene editing technologies as they provide the ability to differentiate almost all cell types ...
Koyuncu Irmak, Duygu, Karaöz, Erdal
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The characteristics of human cranial bone marrow mesenchymal stem cells

Neuroscience Letters, 2015
Recently, cell-based therapy has attracted attention for treatment of central nervous system (CNS) disorders. Bone marrow-derived mesenchymal stem cells (BMSCs) are considered to have good engraftment potential. Therefore, more efficient and less invasive methods to obtain donor cells are required.
Katsuhiro Shinagawa, Takafumi Mitsuhara, Takahito Okazaki, Masaaki Takeda, Satoshi Yamaguchi, Takuro Magaki, Yunosuke Okura, Hiroyuki Uwatoko, Yumi Kawahara, Louis Yuge, Kaoru Kurisu   +10 more
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Mesenchymal Stem Cells Derived from Human Bone Marrow

2015
Mesenchymal stem cells are found in a number of tissues and have the potential to differentiate into a range of mesenchymal lineages. This ready availability and multipotent character means that mesenchymal stem cells have become a focus for the field of tissue engineering, particularly for the repair of bone and cartilage.
Oliver F W, Gardner, Mauro, Alini, Martin J, Stoddart   +2 more
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Human amnion mesenchymal stem cells promote proliferation and osteogenic differentiation in human bone marrow mesenchymal stem cells

Journal of Molecular Histology, 2014
Human amnion mesenchymal stem cells (HAMSCs) can be obtained from human amniotic membrane, a highly abundant and readily available tissue. HAMSC sources present fewer ethical issues, have low immunogenicity, anti-inflammatory properties, considerable advantageous characteristics, and are considered an attractive potential treatment material in the ...
Yuli, Wang, Ying, Yin, Fei, Jiang, Ning, Chen   +3 more
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Tissue-engineered bone formation with cryopreserved human bone marrow mesenchymal stem cells

Cryobiology, 2008
Bone marrow mesenchymal stem cells (MSCs) have become the main cell source for bone tissue engineering. It has been reported that cryopreserved human MSCs can maintain their potential for proliferation and osteogenic differentiation in vitro. There are, however, no reports on osteogenesis with cryopreserved human MSCs in vivo. The aim of this study was
Guangpeng, Liu, Chaofeng, Shu, Lei, Cui, Wei, Liu, Yilin, Cao   +4 more
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Clinical Grade Expansion of Human Bone Marrow Mesenchymal Stem Cells

2007
Mesenchymal stem cells or marrow stromal cells (MSCs) represent a multipotent adult cellular population with immunomodulatory functions. In the adult human body, they are present in various niches, but their main source is bone marrow (BM). The regeneration capability of MSCs, their ease to undergo gene modification, as well as their immunosuppressive ...
Sotiropoulou, Panagiota, Perez, Sonia, Papamichail, Michael   +2 more
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Culture and Characterization of Human Bone Marrow Mesenchymal Stem Cells

2007
Bone marrow (BM) mesenchymal stem cells (MSCs) are non-hematopoietic cells capable of generating colonies of plastic-adherent marrow mesenchymal cells, each derived from a single cell termed a colony-forming unit fibroblasts (CFU-Fs). In addition to their role in establishing the marrow microenvironment, these cells have been shown to differentiate ...
Bruno, Delorme, Pierre, Charbord
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Human Fibroblasts Share Immunosuppressive Properties with Bone Marrow Mesenchymal Stem Cells

Journal of Clinical Immunology, 2010
Bone marrow mesenchymal stem cells (BM-MSCs) and adipose tissue-derived stem cells share immunosuppressive capacities, suggesting that the latter could be a general property of stromal cells.To check this hypothesis, we compared human BM-MSC and fibroblasts for their in vitro multi-potentiality, expandability and their immunomodulatory properties under
Sandrine, Cappellesso-Fleury, Bénédicte, Puissant-Lubrano, Pol-André, Apoil, Matthias, Titeux, Peter, Winterton, Louis, Casteilla, Philippe, Bourin, Antoine, Blancher   +7 more
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Gene delivery to human bone marrow mesenchymal stem cells by microporation

Journal of Biotechnology, 2011
Electroporation has been considered one of the most efficient non-viral based methods to deliver genes regardless of frequently observed high cell mortality. In this study we used a microporation technique to optimise the delivery of plasmid DNA encoding green fluorescence protein (GFP) to human bone marrow mesenchymal stem cells (BM-MSC).
Catarina, Madeira, Sofia C, Ribeiro, Irina S M, Pinheiro, Sofia A M, Martins, Pedro Z, Andrade, Cláudia L, da Silva, Joaquim M S, Cabral   +6 more
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Knockdown of SIRT6 Enables Human Bone Marrow Mesenchymal Stem Cell Senescence

Rejuvenation Research, 2016
Autologous bone marrow mesenchymal stem cell (BM-MSC) transplantation is a novel strategy for treating ischemic heart disease. However, limited benefits have been reported in aging patients. Rejuvenation of aged human BM-MSCs (hBM-MSCs) could be a means to improve the efficacy of stem cell transplantation in older patients. While it has been shown that
Xiao-Yan, Zhai, Ping, Yan, Jie, Zhang, Hui-Fang, Song, Wen-Juan, Yin, Hui, Gong, Hao, Li, Jun, Wu, Jun, Xie, Ren-Ke, Li   +9 more
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