Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow
The FASEB Journal, 2004ABSTRACT Transdifferentiation is a process whereby one cell type committed to and progressing along a specific developmental lineage switches into another cell type of a different lineage through genetic reprogramming. Even though this process has been well studied and established in amphibian systems, it is unclear if mammalian cells
Lin, Song, Rocky S, Tuan
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Non‐hematopoietic human bone marrow contains long‐lasting, pluripotential mesenchymal stem cells
Journal of Cellular Physiology, 2003AbstractMesenchymal stem cells (MSC) are considered as potential agents for reconstructive and gene‐targeting therapies since they differentiate into various cell‐lineages, exhibit an extended survival once injected into a host, and can easily be transfected with engineered DNA.
Suva, Domizio +6 more
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Microvesicles Derived from Human Bone Marrow Mesenchymal Stem Cells Inhibit Tumor Growth
Stem Cells and Development, 2013Mesenchymal stem cells (MSCs) have opposite effects on tumor growth, being able either to favor angiogenesis and tumor initiation or to inhibit progression of established tumors. Factors produced by MSCs within the tumor microenvironment may be relevant for their biological effects.
BRUNO, Stefania +5 more
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Biological characteristics of human bone marrow mesenchymal stem cell culturedin vitro
Current Medical Science, 2005Some biological characteristics of human bone marrow mesenchymal stem cells (MSCs) cultured in vitro were observed. hMSCs were isolated from bone marrow and purified by density gradient centrifugation method, and then cultured in vitro. The proliferation and growth characteristics of hMSCs were observed in primary and passage culture. MSCs of passage 3
Xian'en, Fa +5 more
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[Optimal culture of human bone marrow mesenchymal stem cells].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2007To optimize the culture conditions of the human bone marrow mesenchymal stem cells (hMSCs).The influence of the primary culture method, planting density, the time of the first medium changing, culture medium and serum concentration on growth of the hMSCs were analyzed.When the other conditions were the same, the density gradient isolation was better ...
Yonggang, Pang +2 more
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[Telomerase activity of human bone marrow mesenchymal stem cells].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2005To investigate the telomerase activity in mesenchymal stem cells (hMSCs) from human bone marrow after their in vitro committed differentiation into adipocytes and cryopreservation.hMSCs were isolated from human bone marrow. The isolated hMSCs were induced to differentiate into adipocytes in vitro or cryopreserved.
Jing-yuan, Li +9 more
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Neural Cell Differentiation In Vitro from Adult Human Bone Marrow Mesenchymal Stem Cells
Stem Cells and Development, 2005Bone marrow (BM) mesenchymal stem cells (MSCs) are cells capable of expanding and differentiating in vitro into nonhematopoietic cells. Neurotrophic cytokines, such as human epidermal growth factor (hEGF) and bovine fibroblast growth factor (bFGF) can induce differentiation into neural cells (NCs).
Xiaoxiao, Long +3 more
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Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells
2012Bone marrow-derived mesenchymal stem cells, a subpopulation of the marrow compartment, have remarkable properties that make them an attractive source of cells for regenerative medicine. MSCs are capable of self-renewal, stemness maintenance, and differentiation in cells forming various mesodermal tissues under specific conditions of induction ...
Cucchiarini Magali, Madry Henning
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[Incipient establishment of human bone marrow mesenchymal stem cells bank].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2009To investigate the possibility of establishing the human bone marrow mesenchymal stem cells (hMSCs) bank as to provide an alternative source for the seed cells of tissue engineering.The cell surface antigens of the purified, expanded hMSCs and the ones following cryopreservation were detected by flow cytometry, cultured in a special medium to induce ...
Yonggang, Pang +2 more
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[HLA expression in human fetal bone marrow mesenchymal stem cells].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2008To investigate the expression of human leukocyte antigens (HLA) in human fetal bone marrow mesenchymal stem cells (MSCs) after long time culture as well as the changes in response to interferon-gamma (IFN-gamma) treatment.Human fetal MSCs were collected from 23 to 24-weeks-old fetues with the approval of Ethic Committee of Peking University Health ...
Xiao-lu, Chen +6 more
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