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Cardiomyocytes from Human Embryonic Stem Cells

2013
Human embryonic stem cells (hESCs) are self-renewing and pluripotent cells that can differentiate into functional cardiomyocytes in vitro. Significant progress has been made over the past decade in improving the differentiation and enrichment of hESC-derived cardiomyocytes.
Xiu Qin Xu   +3 more
openaire   +1 more source

Human Embryonic Stem Cell-Derived Cardiomyocytes

2003
The generation of functional cardiomyocytes from human embryonic stem (hES) cells has several potential applications. Myocardial diseases resulting from damage of cardiac tissue affect millions of people, who may benefit from transplantation of cardiomyocytes. Such an application has already been demonstrated in animal models using various cell sources
Chunhui Xu, Melissa K. Carpenter
openaire   +1 more source

Human Embryonic Stem Cell-Derived Cardiomyocytes: Inducing Strategies

Regenerative Medicine, 2006
Cell-based therapy is emerging as an innovative approach for the treatment of degenerative diseases, and stem cells appear to be an ideal source of cells for this. In cardiology, in particular, human embryonic stem cell (hESC)-derived cardiomyocytes theoretically fulfill most, if not all, of the properties of an ideal donor cell, but several critical ...
Pasquale, Gallo, Gianluigi, Condorelli
openaire   +2 more sources

Cardiomyocytes From Human and Mouse Embryonic Stem Cells

2007
Human and mouse embryonic stem (ES) cells have the potential to differentiate to cardiomyocytes in culture. They are therefore of interest for studying early human and mouse heart development, as well as properties of cardiomyocytes from both species, including their responses to cardiac drugs, and, at some point in the future, may represent a source ...
Christine, Mummery   +7 more
openaire   +2 more sources

[The ploidy variability of human cardiomyocytes].

Biulleten' eksperimental'noi biologii i meditsiny, 1990
Unlike literature on ploidy of the human myocytes, DNA content and the number of nuclei have been revealed in the same cells. Besides, the cell ploidy were studied separately in the external, central and inner regions in the left ventricule. Considerable binucleation was revealed in normal and hypertrophic ventricles where 4c X2 was the modal cell ...
V Ia, Brodskiĭ   +4 more
openaire   +1 more source

Human iPSC-Derived Cardiomyocytes

Genetic Engineering & Biotechnology News, 2012
openaire   +1 more source

c-kit+ cells minimally contribute cardiomyocytes to the heart

Nature, 2014
Jop H Van Berlo   +2 more
exaly  

Human myocardial hypertrophy and cardiomyocyte ploidy

Bulletin of Experimental Biology and Medicine, 1992
V. Ya. Brodskii   +4 more
openaire   +1 more source

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