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Cardiomyocytes from Human Embryonic Stem Cells
2013Human embryonic stem cells (hESCs) are self-renewing and pluripotent cells that can differentiate into functional cardiomyocytes in vitro. Significant progress has been made over the past decade in improving the differentiation and enrichment of hESC-derived cardiomyocytes.
Xiu Qin Xu +3 more
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Human Embryonic Stem Cell-Derived Cardiomyocytes
2003The generation of functional cardiomyocytes from human embryonic stem (hES) cells has several potential applications. Myocardial diseases resulting from damage of cardiac tissue affect millions of people, who may benefit from transplantation of cardiomyocytes. Such an application has already been demonstrated in animal models using various cell sources
Chunhui Xu, Melissa K. Carpenter
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Human Embryonic Stem Cell-Derived Cardiomyocytes: Inducing Strategies
Regenerative Medicine, 2006Cell-based therapy is emerging as an innovative approach for the treatment of degenerative diseases, and stem cells appear to be an ideal source of cells for this. In cardiology, in particular, human embryonic stem cell (hESC)-derived cardiomyocytes theoretically fulfill most, if not all, of the properties of an ideal donor cell, but several critical ...
Pasquale, Gallo, Gianluigi, Condorelli
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Cardiomyocytes From Human and Mouse Embryonic Stem Cells
2007Human and mouse embryonic stem (ES) cells have the potential to differentiate to cardiomyocytes in culture. They are therefore of interest for studying early human and mouse heart development, as well as properties of cardiomyocytes from both species, including their responses to cardiac drugs, and, at some point in the future, may represent a source ...
Christine, Mummery +7 more
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[The ploidy variability of human cardiomyocytes].
Biulleten' eksperimental'noi biologii i meditsiny, 1990Unlike literature on ploidy of the human myocytes, DNA content and the number of nuclei have been revealed in the same cells. Besides, the cell ploidy were studied separately in the external, central and inner regions in the left ventricule. Considerable binucleation was revealed in normal and hypertrophic ventricles where 4c X2 was the modal cell ...
V Ia, Brodskiĭ +4 more
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Human iPSC-Derived Cardiomyocytes
Genetic Engineering & Biotechnology News, 2012openaire +1 more source
c-kit+ cells minimally contribute cardiomyocytes to the heart
Nature, 2014Jop H Van Berlo +2 more
exaly
Human myocardial hypertrophy and cardiomyocyte ploidy
Bulletin of Experimental Biology and Medicine, 1992V. Ya. Brodskii +4 more
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