Results 81 to 90 of about 9,526,153 (337)
Connexin 40 promoter-based enrichment of embryonic stem cell-derived cardiovascular progenitor cells [PDF]
, 2008 Background: Pluripotent embryonic stem (ES) cells that can differentiate into functional cardiomyocytes as well as vascular cells in cell culture may open the door to cardiovascular cell transplantation.
David, R. +2 more
core +1 more source
Centrosome Reduction Promotes Terminal Differentiation of Human Cardiomyocytes [PDF]
Stem Cell Reports, 2020 Centrosome reduction and redistribution of pericentriolar material (PCM) coincides with cardiomyocyte transitions to a post-mitotic and matured state. However, it is unclear whether centrosome changes are a cause or consequence of terminal differentiation.
Ng, Dominic C.H. +8 more
openaire +4 more sources
Peroxisomes contribute to intracellular calcium dynamics in cardiomyocytes and non-excitable cells
Life Science Alliance, 2021 Using genetically encoded Förster resonance energy transfer calcium sensors for the peroxisome, this study dissects the previously contentious peroxisome involvement in calcium handling in HeLa cells and in cardiomyocytes derived from human induced ...
Yelena Sargsyan +5 more
doaj +1 more source
New perspectives to repair a broken heart [PDF]
, 2009 The aim of cardiac cell therapy is to restore at least in part the functionality of the diseased or injured myocardium by the use of stem/ progenitor cells.
BARILE, Lucio +9 more
core +1 more source
Cronos Titin is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function
Circulation, 2019 Background: The giant sarcomere protein titin is important in both heart health and disease. Mutations in the gene encoding for titin, TTN, are the leading known cause of familial dilated cardiomyopathy.
R. Zaunbrecher +14 more
semanticscholar +1 more source
Myofilament Degradation and Dysfunction of Human Cardiomyocytes in Fabry Disease [PDF]
The American Journal of Pathology, 2008 Early detection of myocardial dysfunction in Fabry disease (FD) cardiomyopathy suggests the contribution of myofilament structural alterations. Six males with untreated FD cardiomyopathy submitted to cardiac studies, including tissue Doppler imaging and left ventricular endomyocardial biopsy.
CHIMENTI, CRISTINA +10 more
openaire +4 more sources
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
Estrogen Protects the Female Heart from Ischemia/Reperfusion Injury through Manganese Superoxide Dismutase Phosphorylation by Mitochondrial p38β at Threonine 79 and Serine 106. [PDF]
, 2016 A collective body of evidence indicates that estrogen protects the heart from myocardial ischemia/reperfusion (I/R) injury, but the underlying mechanism remains incompletely understood. We have previously delineated a novel mechanism of how 17β-estradiol
Kim, Jin Kyung, Liu, Han, Luo, Tao
core +1 more source
Advanced Functional Materials, EarlyView.A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
Merits of hiPSC-Derived Cardiomyocytes for In Vitro Research and Testing Drug Toxicity
Biomedicines, 2022 The progress of medical technology and scientific advances in the field of anticancer treatment have increased the survival probabilities and duration of life of patients.
Ping-Hsien Wang +3 more
doaj +1 more source