Results 71 to 80 of about 192,493 (241)

Genital manifestations of tropical diseases [PDF]

open access: yes, 2004
Genital symptoms in tropical countries and among returned travellers can arise from a variety of bacterial, protozoal, and helminthic infections which are not usually sexually transmitted.
Richens, J
core   +2 more sources

Serum human epididymis protein 4 levels in colorectal cancer patients

open access: yesMolecular and Clinical Oncology, 2017
Tumour markers are widely used for the diagnosis, staging and monitoring of colorectal cancer (CRC) patients in clinical practice. Carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) are the most frequently used biomarkers in CRC patients.
Yasemi N, Kemal   +7 more
openaire   +3 more sources

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

open access: yesAdvanced Sensor Research, EarlyView.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan   +4 more
wiley   +1 more source

Sperm parameters and epididymis function in transgenic rats overexpressing the Ca-2-binding protein regucalcin: a hidden role for Ca-2 in sperm maturation? [PDF]

open access: yes, 2013
Sperm undergo maturation acquiring progressive motility and the ability to fertilize oocytes through exposure to the components of the epididymal fluid (EF). Although the establishment of a calcium (Ca-2) gradient along the epididymis has been described,
A. V. M. Canario   +46 more
core   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

open access: yesAdvanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li   +19 more
wiley   +1 more source

Evaluation of Vascular Complication and Lack of Glycemic Control as Factors in the Development of Ovarian Cancer in Female Nigerian Type 2 Diabetic Population

open access: yesJournal of Applied Sciences and Environmental Management, 2023
Hypertension and diabetes are important medical conditions that are responsible for a significant number of deaths globally. Therefore, the objective of this study was to assess the human epididymis protein-4 in patients with untreated and treated ...
O. O. Odewusi   +4 more
doaj   +1 more source

Evaluation of Human Epididymis Protein 4, Risk of Ovarian Malignancy Algorithm, and Risk of Malignancy Index Efficiency for Ameliorating Sensitivity and Specificity for Differentiating Benign from Malignant Adnexal Masses

open access: yesJournal of Laboratory Physicians, 2023
Background  Inadequacy of effective sensitive and specific screening modalities results in late-stage diagnosis of ovarian cancer. Cancer Antigen-125 (CA-125) individually possesses limited specificity for differentiating adnexal masses.
Sonia Chawla   +4 more
semanticscholar   +1 more source

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

open access: yesAdvanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang   +22 more
wiley   +1 more source

Postoperative human epididymis protein 4 predicts primary therapy outcome in advanced epithelial ovarian cancer

open access: yesTumor Biology, 2017
Primary chemotherapy treatment response monitoring in advanced epithelial ovarian cancer (EOC) is currently based on CT-imaging and serum CA125 values. Serum HE4 profile during first line chemotherapy has not been previously studied. We evaluated the HE4
Tuulia Vallius   +6 more
doaj   +1 more source

Interaction of HE4 and ANXA2 exists in various malignant cells—HE4–ANXA2–MMP2 protein complex promotes cell migration

open access: yesCancer Cell International, 2019
Background The interaction between human epididymis protein 4 (HE4) and annexin A2 (Annexin A2) has been found in ovarian cancer. However, it is dimness whether the interaction exists in other malignant tumors. Methods Real-time PCR, western blotting and
Jing Wang   +9 more
doaj   +1 more source

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