Human Herpesvirus 6A Induces Dendritic Cell Death and HMGB1 Release without Virus Replication [PDF]
Pathogens, 2021 Human herpesvirus 6A (HHV-6A) is a common virus that has important immunomodulatory effects. Dendritic cells (DC) are key players in innate and adaptive immunity and are implicated in the pathogenesis of many human diseases, including infections.
Rasmus Gustafsson
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Human Herpesvirus 6A Is a Risk Factor for Multiple Sclerosis [PDF]
Frontiers in Immunology, 2022 The role for human herpesvirus (HHV)-6A or HHV-6B in multiple sclerosis (MS) pathogenesis has been controversial. Possibly because the damage of the virus infection may occur before onset of clinical symptoms and because it has been difficult to detect ...
Wangko Lundström, Rasmus Gustafsson
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Herpes simplex virus 1 rhombencephalitis in a patient with chromosomally integrated human herpesvirus-6A [PDF]
IDCases, 2020 Central nervous system infection caused by Herpes simplex virus 1 remains a significant cause of morbidity and mortality in transplant patients. Additionally, the clinical implications of the recently discovered Human herpesvirus 6A are still under ...
Raquel Silva +3 more
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ESCRT-III is recruited by human herpesvirus 6A nuclear egress complex to promote nuclear egress of the nucleocapsid [PDF]
Journal of VirologyHerpesviruses replicate their genomes and package them into capsids within the host cell nucleus. These capsids must then translocate from the nucleus to the cytoplasm through a process designated nuclear egress. The virus-encoded nuclear egress complex (
Aila Gulijiahani +5 more
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Human Herpesvirus 6A Infection-Associated Acute Anterior Uveitis [PDF]
Journal of Inflammation ResearchHuiling Ma,1 Xinyun Wang,1 Ying Chen,1 Yun Zhang,2 Weina Ren,3 Yan Sheng1 1Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, 310003, People’s Republic of China; 2Department ...
Ma H +5 more
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Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A [PDF]
Frontiers in Microbiology, 2019 Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Anthony J. Saviola +12 more
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LYMPHOPROLIFERATIVE SYNDROMES ASSOCIATED WITH HUMAN HERPESVIRUS-6A AND HUMAN HERPESVIRUS-6B [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2018 Human herpesvirus 6A and 6B (HHV-6A and HHV-6B) have been noted since their discovery for their T-lymphotropism. Although it has proven difficult to determine the extent to which HHV-6A and HHV-6B are involved in the pathogenesis of many diseases ...
Eva Eliassen +3 more
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Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration [PDF]
Viruses, 2018 Human herpesvirus-6A and -6B (HHV-6A and -6B) are two closely related betaherpesviruses that infect humans. Upon primary infection they establish a life-long infection termed latency, where the virus genome is integrated into the telomeres of latently ...
Darren J. Wight +5 more
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Human herpesvirus 6A active infection in patients with autoimmune Hashimoto's thyroiditis [PDF]
Brazilian Journal of Infectious Diseases, 2019 Background: Hypothyroidism due to Hashimoto's thyroiditis (HT) is the commonest autoimmune endocrine illness in which antibodies against thyroid organ result in inflammation.
Noorossadat Seyyedi +9 more
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Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling. [PDF]
PLoS Pathogens, 2020 Human herpesvirus 6 (HHV-6) is an important immunosuppressive and immunomodulatory virus worldwide. However, whether and how HHV-6 infection influences the metabolic machinery of the host cell to provide the energy and biosynthetic resources for virus ...
Zhisheng Wu +10 more
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