Crystal Structure of the DNA-Binding Domain of Human Herpesvirus 6A Immediate Early Protein 2. [PDF]
Nishimura M +4 more
europepmc +1 more source
Human Herpesvirus 6A Exhibits Restrictive Propagation with Limited Activation of the Protein Kinase R-eIF2α Stress Pathway. [PDF]
Sharon E, Frenkel N.
europepmc +1 more source
Copy Number Heterogeneity, Large Origin Tandem Repeats, and Interspecies Recombination in Human Herpesvirus 6A (HHV-6A) and HHV-6B Reference Strains. [PDF]
Greninger AL +12 more
europepmc +1 more source
Analyses of Tissue Culture Adaptation of Human Herpesvirus-6A by Whole Genome Deep Sequencing Redefines the Reference Sequence and Identifies Virus Entry Complex Changes. [PDF]
Tweedy JG +3 more
europepmc +1 more source
Maturation of human herpesvirus 6A glycoprotein O requires coexpression of glycoprotein H and glycoprotein L. [PDF]
Tang H, Mahmoud NF, Mori Y.
europepmc +1 more source
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Acute human herpesvirus-6A infection of human mesothelial cells modulates HLA molecules
Archives of Virology, 2015Human herpesvirus 6A (HHV-6A) causes ubiquitous infections and has been associated with several diseases in immunosuppressed and immune dysregulated individuals. Although considered a lymphotropic virus, HHV-6A has the potential to infect many cell types, inducing important alterations in the infected cell.
CASELLI, Elisabetta +7 more
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Familial case of inherited human herpesvirus 6A with phylogenetic assessment
Medicine of Extreme Situations, 2023The paper reports a familial case of HHV-6A chromosomal integration being an important and relevant issue of genetics and medicine. The study was aimed to test the hypothesis of HHV-6A chromosomal integration and vertical transmission in patient with persistent virus detection during recurrent respiratory diseases and the asymptomatic period when there
OV Goleva +8 more
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Human herpesvirus 6A U27 plays an essential role for the virus propagation
Microbiology and Immunology, 2020AbstractHuman herpesvirus 6A (HHV‐6A) is a member of the genus Roseolovirus and the subfamily Betaherpesvirinae. It is similar to and human cytomegalovirus (HCMV). HHV‐6A encodes a 41 kDa nuclear phosphoprotein, U27, which acts as a processivity factor in the replication of the viral DNA.
Anna Lystia Poetranto +5 more
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Identification of stimuli that enhance human herpesvirus 6A (HHV-6A) replication and reconstitution
Journal of VirologyABSTRACT Despite the availability of bacterial artificial chromosome (BAC) systems for human herpesvirus 6A (HHV-6A), reconstitution of infectious viruses is very challenging and time consuming. In this study, we developed approaches to improve the reconstitution process and enhance virus replication to overcome ...
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