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Copy Number Heterogeneity, Large Origin Tandem Repeats, and Interspecies Recombination in Human Herpesvirus 6A (HHV-6A) and HHV-6B Reference Strains. [PDF]

open access: yesJ Virol, 2018
Greninger AL   +12 more
europepmc   +1 more source
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Acute human herpesvirus-6A infection of human mesothelial cells modulates HLA molecules

Archives of Virology, 2015
Human herpesvirus 6A (HHV-6A) causes ubiquitous infections and has been associated with several diseases in immunosuppressed and immune dysregulated individuals. Although considered a lymphotropic virus, HHV-6A has the potential to infect many cell types, inducing important alterations in the infected cell.
CASELLI, Elisabetta   +7 more
openaire   +3 more sources

Familial case of inherited human herpesvirus 6A with phylogenetic assessment

Medicine of Extreme Situations, 2023
The paper reports a familial case of HHV-6A chromosomal integration being an important and relevant issue of genetics and medicine. The study was aimed to test the hypothesis of HHV-6A chromosomal integration and vertical transmission in patient with persistent virus detection during recurrent respiratory diseases and the asymptomatic period when there
OV Goleva   +8 more
openaire   +1 more source

Human herpesvirus 6A U27 plays an essential role for the virus propagation

Microbiology and Immunology, 2020
AbstractHuman herpesvirus 6A (HHV‐6A) is a member of the genus Roseolovirus and the subfamily Betaherpesvirinae. It is similar to and human cytomegalovirus (HCMV). HHV‐6A encodes a 41 kDa nuclear phosphoprotein, U27, which acts as a processivity factor in the replication of the viral DNA.
Anna Lystia Poetranto   +5 more
openaire   +2 more sources

Identification of stimuli that enhance human herpesvirus 6A (HHV-6A) replication and reconstitution

Journal of Virology
ABSTRACT Despite the availability of bacterial artificial chromosome (BAC) systems for human herpesvirus 6A (HHV-6A), reconstitution of infectious viruses is very challenging and time consuming. In this study, we developed approaches to improve the reconstitution process and enhance virus replication to overcome ...
Jana Reich   +3 more
openaire   +2 more sources

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